{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Botanicals",
    "query": {
      "intervention": "Botanicals"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 120,
    "total_pages": 12,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Botanicals&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T17:40:28.833Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06097871",
      "title": "RCT of an Oral Acne Supplement for Adult Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acne"
      ],
      "interventions": [
        {
          "name": "Skin Nutraceutical Supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo pill",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Nutraceutical Wellness Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 102,
      "start_date": "2024-01-15",
      "completion_date": "2024-07-25",
      "has_results": false,
      "last_update_posted_date": "2024-09-25",
      "last_synced_at": "2026-09-05T17:40:28.833Z",
      "location_count": 1,
      "location_summary": "High Point, North Carolina",
      "locations": [
        {
          "city": "High Point",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06097871"
    },
    {
      "nct_id": "NCT07792967",
      "title": "Physical Activity Modifies Exercise Responsiveness",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multimorbidity"
      ],
      "interventions": [
        {
          "name": "SLIMM - Sit less, interact, move more",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PB125",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2027-01-01",
      "completion_date": "2031-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-28",
      "last_synced_at": "2026-09-05T17:40:28.833Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07792967"
    },
    {
      "nct_id": "NCT07426120",
      "title": "Efficacy and Safety of a Botanical Total Coumarin (TC) Cream in Treating Patients With Psoriasis Vulgaris (PLANTCOAT-III)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Psoriasis Vulgaris",
        "Topical Administration",
        "Phase III"
      ],
      "interventions": [
        {
          "name": "Total coumarin (TC) cream",
          "type": "DRUG"
        },
        {
          "name": "Vehicle cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Psoriasis Research Institute of Guangzhou",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 300,
      "start_date": "2026-02-01",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-23",
      "last_synced_at": "2026-09-05T17:40:28.833Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07426120"
    },
    {
      "nct_id": "NCT02395978",
      "title": "A Phase II Study of PDC-1421 Capsule to Evaluate the Safety and Efficacy in Patients With Major Depressive Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "PDC-1421 Capsule",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "BioLite, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "20 Years to 65 Years"
      },
      "enrollment_count": 72,
      "start_date": "2015-04-10",
      "completion_date": "2019-03-18",
      "has_results": true,
      "last_update_posted_date": "2021-07-22",
      "last_synced_at": "2026-09-05T17:40:28.833Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02395978"
    },
    {
      "nct_id": "NCT06366503",
      "title": "Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Photoaging",
        "Wrinkle",
        "Skin Laxity"
      ],
      "interventions": [
        {
          "name": "Fractional Ablative CO2 Laser",
          "type": "PROCEDURE"
        },
        {
          "name": "Facial Cleanser",
          "type": "OTHER"
        },
        {
          "name": "Facial Moisturizer",
          "type": "OTHER"
        },
        {
          "name": "Sunscreen",
          "type": "OTHER"
        },
        {
          "name": "Basic Ointment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Revision Skincare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 65 Years · Female only"
      },
      "enrollment_count": 23,
      "start_date": "2023-10-03",
      "completion_date": "2023-12-29",
      "has_results": false,
      "last_update_posted_date": "2025-08-03",
      "last_synced_at": "2026-09-05T17:40:28.833Z",
      "location_count": 1,
      "location_summary": "Blue Ash, Ohio",
      "locations": [
        {
          "city": "Blue Ash",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06366503"
    },
    {
      "nct_id": "NCT00982787",
      "title": "Safety and Anticonvulsant Efficacy of Passiflora Incarnata Extract in Patients With Partial Epilepsy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Partial Epilepsy"
      ],
      "interventions": [
        {
          "name": "Botanical extract from Passiflora incarnata",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2009-09",
      "completion_date": "2011-01",
      "has_results": false,
      "last_update_posted_date": "2019-08-13",
      "last_synced_at": "2026-09-05T17:40:28.833Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00982787"
    },
    {
      "nct_id": "NCT02313545",
      "title": "Phase I-B Study to Evaluate the Safety, Tolerability and Efficacy of IZN-6NVS for the Treatment of AV and DIV",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Atrophic Vaginitis"
      ],
      "interventions": [
        {
          "name": "IZN-6NVS Cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Izun Pharma Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 50,
      "start_date": "2014-12",
      "completion_date": "2017-03",
      "has_results": false,
      "last_update_posted_date": "2018-03-14",
      "last_synced_at": "2026-09-05T17:40:28.833Z",
      "location_count": 2,
      "location_summary": "The Bronx, New York • Seattle, Washington",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02313545"
    },
    {
      "nct_id": "NCT00010465",
      "title": "Nervous System Manipulation and Botanicals for the Treatment of Recurrent Ear Infections in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Otitis Media"
      ],
      "interventions": [
        {
          "name": "Craniosacral Osteopathic Manipulative Treatment",
          "type": "PROCEDURE"
        },
        {
          "name": "Botanicals",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "National Center for Complementary and Integrative Health (NCCIH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "60 Months",
        "sex": "ALL",
        "summary": "12 Months to 60 Months"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": "2002-12",
      "has_results": false,
      "last_update_posted_date": "2013-03-22",
      "last_synced_at": "2026-09-05T17:40:28.833Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00010465"
    },
    {
      "nct_id": "NCT00303238",
      "title": "Study to Evaluate the Effect of Botanical Dietary Supplements on Inflammation in Healthy People",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Rose hips extract + blueberry/blackberry extract + resveravine",
          "type": "DRUG"
        },
        {
          "name": "Rose hips extract + blueberry/blackberry extract + Aframomum melegueta extract",
          "type": "DRUG"
        },
        {
          "name": "Rose hips extract + resveravine + Aframomum melegueta extract",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Access Business Group",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2004-10",
      "completion_date": "2005-12",
      "has_results": false,
      "last_update_posted_date": "2006-03-16",
      "last_synced_at": "2026-09-05T17:40:28.833Z",
      "location_count": 8,
      "location_summary": "Artesia, California • Buena Park, California • Burbank, California + 4 more",
      "locations": [
        {
          "city": "Artesia",
          "state": "California"
        },
        {
          "city": "Buena Park",
          "state": "California"
        },
        {
          "city": "Buena Park",
          "state": "California"
        },
        {
          "city": "Burbank",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00303238"
    },
    {
      "nct_id": "NCT02909686",
      "title": "Effects of Botanical Microglia Modulators in Gulf War Illness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gulf War Illness"
      ],
      "interventions": [
        {
          "name": "Boswellia Serrata",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Curcumin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Epimedium",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Fisetin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Luteolin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Nettle",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Pycnogenol",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Reishi Mushroom",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Resveratrol",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "39 Years",
        "maximum_age": "65 Years",
        "sex": "MALE",
        "summary": "39 Years to 65 Years · Male only"
      },
      "enrollment_count": 36,
      "start_date": "2016-07",
      "completion_date": "2022-09",
      "has_results": true,
      "last_update_posted_date": "2025-01-24",
      "last_synced_at": "2026-09-05T17:40:28.833Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02909686"
    }
  ]
}