{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Brain+Games+and+Puzzles",
    "query": {
      "intervention": "Brain Games and Puzzles"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-13T21:51:04.008Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07313709",
      "title": "Measuring the Feasibility and Effect of a Virtual Reality Cognitive Training Intervention for Brain Cancer Survivors.",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Brain Cancer"
      ],
      "interventions": [
        {
          "name": "Virtual Reality System",
          "type": "OTHER"
        },
        {
          "name": "Word Search Puzzles",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2026-01-01",
      "completion_date": "2027-05-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-02",
      "last_synced_at": "2026-09-13T21:51:04.008Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07313709"
    },
    {
      "nct_id": "NCT03095417",
      "title": "Improving the Recovery and Outcome Every Day After the ICU",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Delirium",
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Physical Exercise Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Training Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stretching Control",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 249,
      "start_date": "2017-09-25",
      "completion_date": "2022-12-15",
      "has_results": true,
      "last_update_posted_date": "2024-03-27",
      "last_synced_at": "2026-09-13T21:51:04.008Z",
      "location_count": 6,
      "location_summary": "Avon, Indiana • Carmel, Indiana • Fishers, Indiana + 1 more",
      "locations": [
        {
          "city": "Avon",
          "state": "Indiana"
        },
        {
          "city": "Carmel",
          "state": "Indiana"
        },
        {
          "city": "Fishers",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03095417"
    },
    {
      "nct_id": "NCT02230605",
      "title": "Perioperative Cognitive Protection - Cognitive Exercise and Cognitive Reserve (The Neurobics Trial)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Delirium"
      ],
      "interventions": [
        {
          "name": "Mini-Mental State Examination",
          "type": "OTHER"
        },
        {
          "name": "Self-Administered Gerocognitive Examination",
          "type": "OTHER"
        },
        {
          "name": "Geriatric Depression Scale",
          "type": "OTHER"
        },
        {
          "name": "Charlson Comorbidity Index",
          "type": "OTHER"
        },
        {
          "name": "Short Form 36 Health Survey",
          "type": "OTHER"
        },
        {
          "name": "Confusion Assessment Method",
          "type": "OTHER"
        },
        {
          "name": "Memorial Delirium Assessment Scale",
          "type": "OTHER"
        },
        {
          "name": "Postoperative Quality of Recovery Scale",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 322,
      "start_date": "2015-07",
      "completion_date": "2019-08-20",
      "has_results": false,
      "last_update_posted_date": "2019-09-11",
      "last_synced_at": "2026-09-13T21:51:04.008Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02230605"
    },
    {
      "nct_id": "NCT04790630",
      "title": "Cognitive Fitness for Depression in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression Mild",
        "Depressive Disorder, Major",
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Computerized Cognitive Remediation of Executive Functioning (CCR-EF)",
          "type": "OTHER"
        },
        {
          "name": "Active Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2020-11-15",
      "completion_date": "2024-10-15",
      "has_results": true,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-09-13T21:51:04.008Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04790630"
    },
    {
      "nct_id": "NCT03895346",
      "title": "Mental Training for Adults With Mild Cognitive Impairment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Aging"
      ],
      "interventions": [
        {
          "name": "Mindfulness",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Brain Games and Puzzles",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "50 Years to 90 Years"
      },
      "enrollment_count": 22,
      "start_date": "2019-04-10",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2022-09-15",
      "last_synced_at": "2026-09-13T21:51:04.008Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03895346"
    },
    {
      "nct_id": "NCT05965752",
      "title": "RECOVER-NEURO: Platform Protocol to Measure the Effects of Cognitive Dysfunction Interventions on Long COVID Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Long COVID",
        "Long COVID-19",
        "Long COVID19"
      ],
      "interventions": [
        {
          "name": "BrainHQ/Active Comparator Activity",
          "type": "OTHER"
        },
        {
          "name": "BrainHQ",
          "type": "OTHER"
        },
        {
          "name": "PASC CoRE",
          "type": "OTHER"
        },
        {
          "name": "tDCS-active",
          "type": "DEVICE"
        },
        {
          "name": "tDCS-sham",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 328,
      "start_date": "2023-09-01",
      "completion_date": "2024-06-10",
      "has_results": true,
      "last_update_posted_date": "2025-07-18",
      "last_synced_at": "2026-09-13T21:51:04.008Z",
      "location_count": 24,
      "location_summary": "Phoenix, Arizona • Tucson, Arizona • Los Angeles, California + 20 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05965752"
    },
    {
      "nct_id": "NCT05965739",
      "title": "RECOVER-NEURO: Platform Protocol, Appendix_A to Measure the Effects of BrainHQ, PASC CoRE and tDCS Interventions on Long COVID Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Long COVID",
        "Long Covid19",
        "Long Covid-19"
      ],
      "interventions": [
        {
          "name": "BrainHQ/Active Comparator Activity",
          "type": "OTHER"
        },
        {
          "name": "BrainHQ",
          "type": "OTHER"
        },
        {
          "name": "PASC CoRE",
          "type": "OTHER"
        },
        {
          "name": "tDCS-active",
          "type": "DEVICE"
        },
        {
          "name": "tDCS-sham",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 328,
      "start_date": "2023-09-01",
      "completion_date": "2024-12-17",
      "has_results": true,
      "last_update_posted_date": "2026-08-11",
      "last_synced_at": "2026-09-13T21:51:04.008Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05965739"
    },
    {
      "nct_id": "NCT05924490",
      "title": "Cognitive Engagement and Aging Mind",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Age-related Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "Real-time strategy-based videogame training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Semantic Knowledge training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Texas at Dallas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 58,
      "start_date": "2013-01-31",
      "completion_date": "2018-10-01",
      "has_results": false,
      "last_update_posted_date": "2023-06-29",
      "last_synced_at": "2026-09-13T21:51:04.008Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05924490"
    },
    {
      "nct_id": "NCT05498493",
      "title": "Cognitive Rehabilitation for Post-COVID-19 Cognitive Impairment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Cognitive Rehabilitation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Brain Health Education Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 67,
      "start_date": "2022-09-19",
      "completion_date": "2024-08-20",
      "has_results": false,
      "last_update_posted_date": "2024-09-27",
      "last_synced_at": "2026-09-13T21:51:04.008Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05498493"
    }
  ]
}