{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Brinzolamide+1%25", "query": { "intervention": "Brinzolamide 1%" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 23, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Brinzolamide+1%25&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-28T23:05:57.613Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02419508", "title": "SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Open-Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Brinzolamide 1%/brimonidine 0.2% tartrate ophthalmic suspension", "type": "DRUG" }, { "name": "Brinz/brim vehicle", "type": "DRUG" }, { "name": "Prostaglandin analogue", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 290, "start_date": "2015-08-07", "completion_date": "2018-02-27", "has_results": true, "last_update_posted_date": "2018-11-15", "last_synced_at": "2026-09-28T23:05:57.613Z", "location_count": 1, "location_summary": "Fort Worth, Texas", "locations": [ { "city": "Fort Worth", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02419508" }, { "nct_id": "NCT02730871", "title": "Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV®", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Open-angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Brinzolamide 1%/brimonidine tartrate 0.2% ophthalmic suspension", "type": "DRUG" }, { "name": "Brinzolamide/brimonidine vehicle", "type": "DRUG" }, { "name": "Travoprost 0.004%/timolol 0.5% solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 173, "start_date": "2016-06-24", "completion_date": "2018-07-13", "has_results": true, "last_update_posted_date": "2019-05-29", "last_synced_at": "2026-09-28T23:05:57.613Z", "location_count": 1, "location_summary": "Fort Worth, Texas", "locations": [ { "city": "Fort Worth", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02730871" }, { "nct_id": "NCT00675207", "title": "Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogs", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Primary Open Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Brimonidine purite 0.15%", "type": "DRUG" }, { "name": "Dorzolamide 2%", "type": "DRUG" }, { "name": "Brinzolamide 1%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Northwestern Ophthalmic Institute S.C.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "41 Years", "maximum_age": null, "sex": "ALL", "summary": "41 Years and older" }, "enrollment_count": 120, "start_date": "2006-01", "completion_date": "2007-07", "has_results": false, "last_update_posted_date": "2008-05-08", "last_synced_at": "2026-09-28T23:05:57.613Z", "location_count": 1, "location_summary": "Glenview, Illinois", "locations": [ { "city": "Glenview", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00675207" }, { "nct_id": "NCT00440141", "title": "Brimonidine 0.1% Versus Brinzolamide 1% as Adjunctive Therapy to Latanoprost 0.005%", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "latanoprost 0.005% eye drops and brimonidine 0.1% eye drops", "type": "DRUG" }, { "name": "latanoprost 0.005% eye drops and brinzolamide 1.0% eye drops", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Allergan", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2006-07", "completion_date": "2007-03", "has_results": false, "last_update_posted_date": "2008-01-02", "last_synced_at": "2026-09-28T23:05:57.613Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00440141" }, { "nct_id": "NCT00759941", "title": "A Comparison of Azopt Versus Placebo Added to Xalatan in Patients With Elevated Intraocular Pressure (IOP) on a Prostaglandin", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Glaucoma" ], "interventions": [ { "name": "Brinzolamide 1% ophthalmic solution (Azopt)", "type": "DRUG" }, { "name": "Placebo eye drops", "type": "DRUG" }, { "name": "Latanoprost 0.005% ophthalmic solution (Xalatan)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "35 Years", "maximum_age": null, "sex": "ALL", "summary": "35 Years and older" }, "enrollment_count": 86, "start_date": "2007-10", "completion_date": "2009-07", "has_results": true, "last_update_posted_date": "2014-01-13", "last_synced_at": "2026-09-28T23:05:57.613Z", "location_count": 1, "location_summary": "Fort Worth, Texas", "locations": [ { "city": "Fort Worth", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00759941" }, { "nct_id": "NCT01507584", "title": "The Effects of the Water Drinking Test on Intraocular Pressure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Glaucoma" ], "interventions": [ { "name": "SENSIMED Triggerfish", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of California, San Diego", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 23, "start_date": "2011-08", "completion_date": "2013-04-30", "has_results": true, "last_update_posted_date": "2019-09-11", "last_synced_at": "2026-09-28T23:05:57.613Z", "location_count": 1, "location_summary": "La Jolla, California", "locations": [ { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01507584" }, { "nct_id": "NCT03896633", "title": "Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Glaucoma", "Open Angle or Ocular Hypertension" ], "interventions": [ { "name": "brinzolamide 1% ophthalmic suspension", "type": "DRUG" }, { "name": "Azopt 1%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bausch & Lomb Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 637, "start_date": "2018-02-28", "completion_date": "2018-11-17", "has_results": true, "last_update_posted_date": "2023-05-09", "last_synced_at": "2026-09-28T23:05:57.613Z", "location_count": 1, "location_summary": "Bridgewater, New Jersey", "locations": [ { "city": "Bridgewater", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT03896633" }, { "nct_id": "NCT00314158", "title": "A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Open-angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Brinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspension", "type": "DRUG" }, { "name": "Brinzolamide 10 mg/ml (AZOPT) eye drops, suspension", "type": "DRUG" }, { "name": "Timolol 5 mg/ml eye drops, solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 523, "start_date": "2005-11", "completion_date": "2007-01", "has_results": false, "last_update_posted_date": "2016-11-18", "last_synced_at": "2026-09-28T23:05:57.613Z", "location_count": 1, "location_summary": "Fort Worth, Texas", "locations": [ { "city": "Fort Worth", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00314158" }, { "nct_id": "NCT02348476", "title": "A Study of Simbrinza™ Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Open-Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "No Intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Allergan", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 150, "start_date": "2014-11", "completion_date": "2015-04", "has_results": false, "last_update_posted_date": "2015-09-21", "last_synced_at": "2026-09-28T23:05:57.613Z", "location_count": 1, "location_summary": "Wheaton, Illinois", "locations": [ { "city": "Wheaton", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02348476" }, { "nct_id": "NCT04024072", "title": "To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Glaucoma, Open-Angle", "Ocular Hypertension" ], "interventions": [ { "name": "Brinzolamide 1% ophthalmic suspension", "type": "DRUG" }, { "name": "Azopt 1% Ophthalmic Suspension", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Padagis LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 495, "start_date": "2019-06-24", "completion_date": "2020-04-30", "has_results": true, "last_update_posted_date": "2023-03-06", "last_synced_at": "2026-09-28T23:05:57.613Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT04024072" } ] }