{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Broccoli+seed+extract",
    "query": {
      "intervention": "Broccoli seed extract"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T21:40:57.993Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03289832",
      "title": "Effect of Orally Delivered Phytochemicals on Aging and Inflammation in the Skin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Adults"
      ],
      "interventions": [
        {
          "name": "Crucera-SGS",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Meriva 500-SF",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 25,
      "start_date": "2017-09-25",
      "completion_date": "2019-10-23",
      "has_results": false,
      "last_update_posted_date": "2020-07-21",
      "last_synced_at": "2026-09-02T21:40:57.993Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03289832"
    },
    {
      "nct_id": "NCT05745636",
      "title": "Broccoli Seed Extract and Skin Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Inflammation"
      ],
      "interventions": [
        {
          "name": "Broccoli, mustard, vitamin C",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Appalachian State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "57 Years",
        "sex": "ALL",
        "summary": "25 Years to 57 Years"
      },
      "enrollment_count": 24,
      "start_date": "2023-03-13",
      "completion_date": "2023-07-30",
      "has_results": false,
      "last_update_posted_date": "2023-12-20",
      "last_synced_at": "2026-09-02T21:40:57.993Z",
      "location_count": 1,
      "location_summary": "Kannapolis, North Carolina",
      "locations": [
        {
          "city": "Kannapolis",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05745636"
    },
    {
      "nct_id": "NCT03402230",
      "title": "Broccoli Sprout/Broccoli Seed Extract Supplement in Decreasing Toxicity in Heavy Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Cigarette Smoking-Related Carcinoma",
        "Tobacco-Related Carcinoma"
      ],
      "interventions": [
        {
          "name": "Broccoli Sprout/Broccoli Seed Extract Supplement",
          "type": "DRUG"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2018-02-20",
      "completion_date": "2022-07-24",
      "has_results": true,
      "last_update_posted_date": "2023-06-28",
      "last_synced_at": "2026-09-02T21:40:57.993Z",
      "location_count": 2,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03402230"
    },
    {
      "nct_id": "NCT02909959",
      "title": "Sulforaphane for the Treatment of Young Men With Autism Spectrum Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Autism Spectrum Disorder",
        "Autistic Disorder",
        "Neurodevelopmental Disorder",
        "Childhood Developmental Disorders, Pervasive"
      ],
      "interventions": [
        {
          "name": "Sulforaphane",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "30 Years",
        "sex": "MALE",
        "summary": "13 Years to 30 Years · Male only"
      },
      "enrollment_count": 48,
      "start_date": "2017-03-01",
      "completion_date": "2019-05-30",
      "has_results": true,
      "last_update_posted_date": "2020-06-04",
      "last_synced_at": "2026-09-02T21:40:57.993Z",
      "location_count": 1,
      "location_summary": "Carrboro, North Carolina",
      "locations": [
        {
          "city": "Carrboro",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02909959"
    },
    {
      "nct_id": "NCT06009926",
      "title": "Evaluation of Broccoli Seed and Sprout Extract for Detoxification of Carcinogens in Firefighters",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hematopoietic and Lymphatic System Neoplasm",
        "Malignant Solid Neoplasm",
        "Occupational Malignant Neoplasm"
      ],
      "interventions": [
        {
          "name": "Acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Biospecimen Collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Broccoli Sprout/Broccoli Seed Extract Supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Administration",
          "type": "DRUG"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE",
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 72,
      "start_date": "2023-12-04",
      "completion_date": "2027-11-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-13",
      "last_synced_at": "2026-09-02T21:40:57.993Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06009926"
    },
    {
      "nct_id": "NCT03420976",
      "title": "Novel Supplement-based Therapy for the Treatment of Small Intestinal Bacterial Overgrowth",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Small Intestinal Bacterial Overgrowth"
      ],
      "interventions": [
        {
          "name": "Novel Supplement Based Therapy",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Atrium Innovations",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "19 Years to 84 Years"
      },
      "enrollment_count": 0,
      "start_date": "2017-12-07",
      "completion_date": "2019-02-01",
      "has_results": false,
      "last_update_posted_date": "2021-01-12",
      "last_synced_at": "2026-09-02T21:40:57.993Z",
      "location_count": 1,
      "location_summary": "Oxford, Ohio",
      "locations": [
        {
          "city": "Oxford",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03420976"
    },
    {
      "nct_id": "NCT04946526",
      "title": "Broccoli Sulforaphane Bioavailability With Mustard",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sulforaphane Bioavailability"
      ],
      "interventions": [
        {
          "name": "Broccoli seed extract",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Broccoli seed extract with mustard seed powder",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Appalachian State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "25 Years to 65 Years"
      },
      "enrollment_count": 16,
      "start_date": "2022-06-01",
      "completion_date": "2022-09-30",
      "has_results": false,
      "last_update_posted_date": "2023-01-25",
      "last_synced_at": "2026-09-02T21:40:57.993Z",
      "location_count": 1,
      "location_summary": "Kannapolis, North Carolina",
      "locations": [
        {
          "city": "Kannapolis",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04946526"
    },
    {
      "nct_id": "NCT05121051",
      "title": "Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cigarette Smoking-Related Carcinoma"
      ],
      "interventions": [
        {
          "name": "Biospecimen Collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Broccoli Sprout/Broccoli Seed Extract Supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Administration",
          "type": "DRUG"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DIETARY_SUPPLEMENT",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 135,
      "start_date": "2022-09-21",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-14",
      "last_synced_at": "2026-09-02T21:40:57.993Z",
      "location_count": 3,
      "location_summary": "Tucson, Arizona • Washington D.C., District of Columbia • Buffalo, New York",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05121051"
    },
    {
      "nct_id": "NCT01598272",
      "title": "Effects of a Proprietary Blend of Herbal Extract Supplement on Cellular Detoxification, Inflammation, and Cumulative Cognitive Index as Well as Gene Expression in Middle-Aged Adult Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anti Aging"
      ],
      "interventions": [
        {
          "name": "Vitality product AM + Vitality product PM",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Pharmanex",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "73 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 73 Years · Female only"
      },
      "enrollment_count": 95,
      "start_date": "2011-07",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2014-12-11",
      "last_synced_at": "2026-09-02T21:40:57.993Z",
      "location_count": 1,
      "location_summary": "Orem, Utah",
      "locations": [
        {
          "city": "Orem",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01598272"
    },
    {
      "nct_id": "NCT03182959",
      "title": "Broccoli Sprout Extract in Preventing Recurrence in Patients With Tobacco-Related Head and Neck Squamous Cell Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "HNSCC",
        "Head and Neck Cancer",
        "Head and Neck Squamous Cell Carcinoma",
        "Tobacco-Related Carcinoma",
        "Carcinoma in Situ",
        "Dysplasia",
        "Hyperplasia",
        "Premalignant Lesion"
      ],
      "interventions": [
        {
          "name": "Avmacol®",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2017-04-24",
      "completion_date": "2021-01-19",
      "has_results": false,
      "last_update_posted_date": "2021-06-21",
      "last_synced_at": "2026-09-02T21:40:57.993Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03182959"
    }
  ]
}