{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Brush&page=5",
    "query": {
      "intervention": "Brush",
      "page": 5
    },
    "page_size": 10
  },
  "pagination": {
    "page": 5,
    "page_size": 10,
    "total_count": 355,
    "total_pages": 36,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Brush&page=6&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Brush&page=4&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-20T07:15:19.873Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02451124",
      "title": "Non-endoscopic Brushing of the Esophagus Using a Non-endoscopic Inflatable Balloon of the Esophagus in Screening for Barrett Esophagus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Barrett Esophagus"
      ],
      "interventions": [
        {
          "name": "non-endoscopic inflatable balloon for the esophagus",
          "type": "DEVICE"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "esophagogastroduodenoscopy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Case Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 156,
      "start_date": "2015-07",
      "completion_date": "2017-01-29",
      "has_results": true,
      "last_update_posted_date": "2019-11-06",
      "last_synced_at": "2026-10-20T07:15:19.873Z",
      "location_count": 2,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02451124"
    },
    {
      "nct_id": "NCT07836998",
      "title": "A Study to Assess the Efficacy of an Experimental Mouthwash Used With a Marketed Whitening Toothpaste on Stain Build-up",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Discoloration"
      ],
      "interventions": [
        {
          "name": "Whitening Toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Experimental Mouthwash",
          "type": "DEVICE"
        },
        {
          "name": "Regular Fluoride Toothpaste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 360,
      "start_date": "2026-09-25",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-10-07",
      "last_synced_at": "2026-10-20T07:15:19.873Z",
      "location_count": 1,
      "location_summary": "Melbourne, Florida",
      "locations": [
        {
          "city": "Melbourne",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07836998"
    },
    {
      "nct_id": "NCT07419763",
      "title": "Intra Oral Appliance (IOA) Model Evaluating the Efficacy of Sensitive Toothpaste",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Negative Control Toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Active Comparator",
          "type": "DRUG"
        },
        {
          "name": "Test toothpaste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Church & Dwight Company, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2025-04-15",
      "completion_date": "2025-06-10",
      "has_results": false,
      "last_update_posted_date": "2026-02-19",
      "last_synced_at": "2026-10-20T07:15:19.873Z",
      "location_count": 1,
      "location_summary": "Noblesville, Indiana",
      "locations": [
        {
          "city": "Noblesville",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07419763"
    },
    {
      "nct_id": "NCT04221334",
      "title": "Clinical Investigation Examining Plaque and Gingivitis Connected Toothbrush Compared to Non-Connected Toothbrush",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis",
        "Plaque, Dental"
      ],
      "interventions": [
        {
          "name": "Electric Toothbrush",
          "type": "DEVICE"
        },
        {
          "name": "oral health care application",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 79,
      "start_date": "2019-04-30",
      "completion_date": "2019-07-27",
      "has_results": false,
      "last_update_posted_date": "2020-01-09",
      "last_synced_at": "2026-10-20T07:15:19.873Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04221334"
    },
    {
      "nct_id": "NCT04591977",
      "title": "Self-Sampling for Human Papillomavirus (HPV) at Well Women Appointments",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HPV"
      ],
      "interventions": [
        {
          "name": "HPV Self-Sampling Kit (Evalyn Brush)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 65 Years · Female only"
      },
      "enrollment_count": 46,
      "start_date": "2021-01-07",
      "completion_date": "2022-11-10",
      "has_results": true,
      "last_update_posted_date": "2023-10-06",
      "last_synced_at": "2026-10-20T07:15:19.873Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04591977"
    },
    {
      "nct_id": "NCT04753996",
      "title": "Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Sclerosing Cholangitis",
        "PSC",
        "Cholangiocarcinoma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 300,
      "start_date": "2021-03-08",
      "completion_date": "2035-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-10-20T07:15:19.873Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04753996"
    },
    {
      "nct_id": "NCT00763269",
      "title": "The Efficacy of a Toothpaste to Reduce Sensitivity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dentin Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "Triclosan, Silicon dioxide, fluoride",
          "type": "DRUG"
        },
        {
          "name": "Triclosan, fluoride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "12 Years to 80 Years"
      },
      "enrollment_count": 626,
      "start_date": "2008-09",
      "completion_date": "2008-12",
      "has_results": true,
      "last_update_posted_date": "2012-03-07",
      "last_synced_at": "2026-10-20T07:15:19.873Z",
      "location_count": 1,
      "location_summary": "Cedar Knolls, New Jersey",
      "locations": [
        {
          "city": "Cedar Knolls",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00763269"
    },
    {
      "nct_id": "NCT04423679",
      "title": "The Selfie Study- Assessing Novel Markers for Cervical Cancer Screening From Self-collected Samples",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Human Papilloma Virus",
        "Cervical Cancer",
        "CIN 2/3"
      ],
      "interventions": [
        {
          "name": "Evalyn Brush",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "George Washington University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "69 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 69 Years · Female only"
      },
      "enrollment_count": 294,
      "start_date": "2020-08-15",
      "completion_date": "2025-06-19",
      "has_results": false,
      "last_update_posted_date": "2026-03-06",
      "last_synced_at": "2026-10-20T07:15:19.873Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04423679"
    },
    {
      "nct_id": "NCT06798441",
      "title": "Determination of the Oral Irritation Potential of a Fluoride Rinse in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Brush Only",
          "type": "OTHER"
        },
        {
          "name": "Brush / Rinse (Jolly Rancher Prototype)",
          "type": "OTHER"
        },
        {
          "name": "Brush / Rinse (LISTERINE® Total Care Zero Alcohol)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer and Personal Products Worldwide",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "6 Years to 11 Years"
      },
      "enrollment_count": 161,
      "start_date": "2025-01-20",
      "completion_date": "2025-02-20",
      "has_results": false,
      "last_update_posted_date": "2025-03-12",
      "last_synced_at": "2026-10-20T07:15:19.873Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06798441"
    },
    {
      "nct_id": "NCT04512482",
      "title": "Evaluation of Oral Plaque Removal Utilizing an Adjunct Enzyme Pre-rinse",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Dental Plaque",
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Bromelain",
          "type": "DRUG"
        },
        {
          "name": "Powdered sugar",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "10 Years to 25 Years"
      },
      "enrollment_count": 46,
      "start_date": "2018-06-14",
      "completion_date": "2019-03-04",
      "has_results": true,
      "last_update_posted_date": "2020-12-03",
      "last_synced_at": "2026-10-20T07:15:19.873Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04512482"
    }
  ]
}