{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bunionectomy", "query": { "intervention": "Bunionectomy" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 78, "total_pages": 8, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bunionectomy&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-03T02:34:24.911Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06215820", "title": "Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Bunionectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Acute Pain", "Post Operative Pain", "Pain" ], "interventions": [ { "name": "MR-107A-02", "type": "DRUG" }, { "name": "Tramadol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Bunionectomy", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Viatris Specialty LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 410, "start_date": "2023-12-29", "completion_date": "2024-09-30", "has_results": false, "last_update_posted_date": "2025-10-14", "last_synced_at": "2026-09-03T02:34:24.911Z", "location_count": 15, "location_summary": "Sheffield, Alabama • Phoenix, Arizona • Anaheim, California + 12 more", "locations": [ { "city": "Sheffield", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Riverside", "state": "California" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06215820" }, { "nct_id": "NCT06423703", "title": "A Study of Cebranopadol for the Treatment of Acute Pain After Bunionectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Acute Pain" ], "interventions": [ { "name": "Cebranopadol", "type": "DRUG" }, { "name": "Oxycodone IR", "type": "DRUG" }, { "name": "Placebo Only", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Tris Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 240, "start_date": "2024-07-18", "completion_date": "2025-01-31", "has_results": false, "last_update_posted_date": "2026-01-26", "last_synced_at": "2026-09-03T02:34:24.911Z", "location_count": 10, "location_summary": "Sheffield, Alabama • Little Rock, Arkansas • Tampa, Florida + 7 more", "locations": [ { "city": "Sheffield", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Tampa", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Overland Park", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06423703" }, { "nct_id": "NCT04398329", "title": "Dose-Escalation Study of HTX-034 Following Bunionectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Bunions", "Postoperative Pain" ], "interventions": [ { "name": "HTX-034 low dose", "type": "DRUG" }, { "name": "HTX-034 high dose", "type": "DRUG" }, { "name": "Luer lock applicator", "type": "DEVICE" }, { "name": "Bupivacaine HCl", "type": "DRUG" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Heron Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 78, "start_date": "2020-05-08", "completion_date": "2021-07-15", "has_results": true, "last_update_posted_date": "2026-06-09", "last_synced_at": "2026-09-03T02:34:24.911Z", "location_count": 4, "location_summary": "Phoenix, Arizona • Bellaire, Texas • San Antonio, Texas + 1 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Bellaire", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT04398329" }, { "nct_id": "NCT04977336", "title": "A Study Evaluating Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acute Pain" ], "interventions": [ { "name": "VX-548", "type": "DRUG" }, { "name": "HB/APAP", "type": "DRUG" }, { "name": "Placebo (matched to VX-548)", "type": "DRUG" }, { "name": "Placebo (matched to HB/APAP)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vertex Pharmaceuticals Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 274, "start_date": "2021-07-19", "completion_date": "2022-03-04", "has_results": true, "last_update_posted_date": "2025-06-25", "last_synced_at": "2026-09-03T02:34:24.911Z", "location_count": 12, "location_summary": "Sheffield, Alabama • Phoenix, Arizona • Anaheim, California + 9 more", "locations": [ { "city": "Sheffield", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "Tarzana", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04977336" }, { "nct_id": "NCT02689063", "title": "Maxigesic IV Phase 3 Bunionectomy Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Post Operative Pain" ], "interventions": [ { "name": "Maxigesic IV", "type": "DRUG" }, { "name": "IV Acetaminophen", "type": "DRUG" }, { "name": "IV Ibuprofen", "type": "DRUG" }, { "name": "Placebo IV", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AFT Pharmaceuticals, Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 276, "start_date": "2016-10-26", "completion_date": "2017-09-15", "has_results": true, "last_update_posted_date": "2021-07-06", "last_synced_at": "2026-09-03T02:34:24.911Z", "location_count": 2, "location_summary": "Pasadena, Maryland • Austin, Texas", "locations": [ { "city": "Pasadena", "state": "Maryland" }, { "city": "Austin", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02689063" }, { "nct_id": "NCT02499575", "title": "Pericapsular Exparel for Pain Relief in Bunionectomy and Related Procedures", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Bunion", "Hallux Rigidus" ], "interventions": [ { "name": "0.5% ropivacaine", "type": "DRUG" }, { "name": "Exparel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "OhioHealth", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2, "start_date": "2015-07", "completion_date": "2016-07", "has_results": true, "last_update_posted_date": "2017-05-17", "last_synced_at": "2026-09-03T02:34:24.911Z", "location_count": 2, "location_summary": "Columbus, Ohio • Westerville, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" }, { "city": "Westerville", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02499575" }, { "nct_id": "NCT02487108", "title": "Study to Evaluate the Analgesic Efficacy and Safety of Hydrocodone Bitartrate/Acetaminophen Immediate-Release Tablets in Participants With Moderate to Severe Pain Following Bunionectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain" ], "interventions": [ { "name": "TV-46763", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Teva Branded Pharmaceutical Products R&D, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 569, "start_date": "2015-08-11", "completion_date": "2016-03-30", "has_results": true, "last_update_posted_date": "2022-03-31", "last_synced_at": "2026-09-03T02:34:24.911Z", "location_count": 8, "location_summary": "Phoenix, Arizona • Anaheim, California • Bakersfield, California + 5 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Bakersfield", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "Pasadena", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT02487108" }, { "nct_id": "NCT07222748", "title": "A Study of TLC590 for Postsurgical Pain Following Bunionectomy", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "TLC590", "type": "DRUG" }, { "name": "Liposomal Bupivacaine", "type": "DRUG" }, { "name": "Saline Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "TLC Biopharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 304, "start_date": "2025-11-17", "completion_date": "2026-07", "has_results": false, "last_update_posted_date": "2026-07-02", "last_synced_at": "2026-09-03T02:34:24.911Z", "location_count": 4, "location_summary": "Miami, Florida • Bellaire, Texas • Houston, Texas + 1 more", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Bellaire", "state": "Texas" }, { "city": "Houston", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07222748" }, { "nct_id": "NCT02815709", "title": "Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Bunionectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Acute Pain" ], "interventions": [ { "name": "Oliceridine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Morphine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Trevena Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 418, "start_date": "2016-05", "completion_date": "2017-01", "has_results": true, "last_update_posted_date": "2020-09-25", "last_synced_at": "2026-09-03T02:34:24.911Z", "location_count": 7, "location_summary": "Phoenix, Arizona • Anaheim, California • Pasadena, California + 4 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "Pasadena", "state": "Maryland" }, { "city": "Austin", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02815709" }, { "nct_id": "NCT06017999", "title": "XG005 for Pain Control in Subjects Undergoing Bunionectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Acute Pain" ], "interventions": [ { "name": "XG005 tablet", "type": "DRUG" }, { "name": "Placebo tablet", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Xgene Pharmaceutical Group", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 450, "start_date": "2023-08-29", "completion_date": "2024-09-30", "has_results": true, "last_update_posted_date": "2025-11-17", "last_synced_at": "2026-09-03T02:34:24.911Z", "location_count": 8, "location_summary": "Phoenix, Arizona • San Diego, California • Hialeah, Florida + 5 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "San Diego", "state": "California" }, { "city": "Hialeah", "state": "Florida" }, { "city": "Dayton", "state": "Ohio" }, { "city": "Bellaire", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06017999" } ] }