{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine&page=28",
    "query": {
      "intervention": "Bupivacaine",
      "page": 28
    },
    "page_size": 10
  },
  "pagination": {
    "page": 28,
    "page_size": 10,
    "total_count": 975,
    "total_pages": 98,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine&page=29&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine&page=27&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-03T13:57:53.323Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03623256",
      "title": "Comparison of Intrathecal Versus Epidural Fentanyl on Fetal Bradycardia in Labor Combined Spinal Epidural Analgesia",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Labor Pain",
        "Obstetric Pain"
      ],
      "interventions": [
        {
          "name": "Spinal fentanyl",
          "type": "DRUG"
        },
        {
          "name": "Spinal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Spinal Fentanyl and Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Epidural fentanyl /spinal bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 558,
      "start_date": "2019-10-28",
      "completion_date": "2023-10-31",
      "has_results": false,
      "last_update_posted_date": "2021-07-22",
      "last_synced_at": "2026-11-03T13:57:53.323Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03623256"
    },
    {
      "nct_id": "NCT03070054",
      "title": "LIA in Hip Arthroscopy Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "20ml 0.25% bupivacaine-epinephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2016-06",
      "completion_date": "2020-03",
      "has_results": false,
      "last_update_posted_date": "2023-05-10",
      "last_synced_at": "2026-11-03T13:57:53.323Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03070054"
    },
    {
      "nct_id": "NCT04198714",
      "title": "Pudendal Nerve Block in Vaginal Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nerve Block",
        "Pain, Postoperative",
        "Pelvic Floor Disorders",
        "Pelvic Organ Prolapse",
        "Pudendal Neuralgia",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "Pudendal block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "MetroHealth Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 80 Years · Female only"
      },
      "enrollment_count": 72,
      "start_date": "2019-08-01",
      "completion_date": "2021-09-13",
      "has_results": true,
      "last_update_posted_date": "2024-08-12",
      "last_synced_at": "2026-11-03T13:57:53.323Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04198714"
    },
    {
      "nct_id": "NCT04518462",
      "title": "Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Lower Extremity Surgery",
        "Bunion",
        "Metatarsophalangeal Fushion",
        "Midfoot Fusion",
        "Hindfoot Fushion",
        "Total Ankle Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Exparel",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine Hydrochloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pacira Pharmaceuticals, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 121,
      "start_date": "2020-10-20",
      "completion_date": "2021-04-05",
      "has_results": true,
      "last_update_posted_date": "2022-07-18",
      "last_synced_at": "2026-11-03T13:57:53.323Z",
      "location_count": 5,
      "location_summary": "Phoenix, Arizona • Pasadena, California • Boston, Massachusetts + 2 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Pasadena",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Chestnut Hill",
          "state": "Massachusetts"
        },
        {
          "city": "Bellaire",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04518462"
    },
    {
      "nct_id": "NCT03878888",
      "title": "Exparel Use in Bilateral TAP Blocks for Postoperative Pain Control",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Postoperative Pain",
        "Surgery",
        "Anesthesia, Local"
      ],
      "interventions": [
        {
          "name": "Exparel 266 MG Per 20 ML Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Luke's Hospital, Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 52,
      "start_date": "2019-01-15",
      "completion_date": "2019-07-01",
      "has_results": false,
      "last_update_posted_date": "2020-12-17",
      "last_synced_at": "2026-11-03T13:57:53.323Z",
      "location_count": 1,
      "location_summary": "Bethlehem, Pennsylvania",
      "locations": [
        {
          "city": "Bethlehem",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03878888"
    },
    {
      "nct_id": "NCT05868330",
      "title": "Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Post Operative Pain",
        "Anesthesia",
        "Nerve Block",
        "Shoulder Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Interscalene Catheter",
          "type": "PROCEDURE"
        },
        {
          "name": "Exparel Single Shot Interscalene Block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Melinda Seering",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 56,
      "start_date": "2024-08-19",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-11-03T13:57:53.323Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05868330"
    },
    {
      "nct_id": "NCT05972681",
      "title": "The PAIN (Pelvic Area Injection for Numbness) Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Vaginal Laceration During Delivery"
      ],
      "interventions": [
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Epinephrine",
          "type": "DRUG"
        },
        {
          "name": "Sham normal saline arm",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 3,
      "start_date": "2025-04-08",
      "completion_date": "2025-10-19",
      "has_results": true,
      "last_update_posted_date": "2026-05-27",
      "last_synced_at": "2026-11-03T13:57:53.323Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05972681"
    },
    {
      "nct_id": "NCT01756573",
      "title": "Dexamethasone and Block Duration in Upper Extremity",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Duration of Pain Relief"
      ],
      "interventions": [
        {
          "name": "Dexamthsone",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 5,
      "start_date": "2013-01",
      "completion_date": "2015-01",
      "has_results": true,
      "last_update_posted_date": "2019-05-14",
      "last_synced_at": "2026-11-03T13:57:53.323Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01756573"
    },
    {
      "nct_id": "NCT00565383",
      "title": "The Effect of Combined Spinal-Epidural Analgesia on the Success of External Cephalic Version (ECV) for Breech Position",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pregnancy",
        "Breech Presentation"
      ],
      "interventions": [
        {
          "name": "Combined spinal-epidural analgesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Intravenous fentanyl (50mcg)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 55 Years · Female only"
      },
      "enrollment_count": 101,
      "start_date": "2002-08",
      "completion_date": "2006-06",
      "has_results": false,
      "last_update_posted_date": "2013-06-13",
      "last_synced_at": "2026-11-03T13:57:53.323Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00565383"
    },
    {
      "nct_id": "NCT02059070",
      "title": "Bupivacaine Versus Ropivacaine on Diaphragmatic Motility and Ventilatory Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Paresis"
      ],
      "interventions": [
        {
          "name": "Ropivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Anesthesiology WSU/DMC-NorthStar",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 39,
      "start_date": "2012-06",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2014-11-25",
      "last_synced_at": "2026-11-03T13:57:53.323Z",
      "location_count": 1,
      "location_summary": "Madison Heights, Michigan",
      "locations": [
        {
          "city": "Madison Heights",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02059070"
    }
  ]
}