{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine+0.25%25&page=3",
    "query": {
      "intervention": "Bupivacaine 0.25%",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 315,
    "total_pages": 32,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine+0.25%25&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine+0.25%25&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-08T00:46:25.477Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04240626",
      "title": "Multimodal Analgesia Effect on Post Surgical Patient",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Obesity, Morbid",
        "Surgery",
        "Bariatric Surgery Candidate"
      ],
      "interventions": [
        {
          "name": "Neurontin",
          "type": "DRUG"
        },
        {
          "name": "Dilaudid Injectable Product",
          "type": "DRUG"
        },
        {
          "name": "Marcaine Injectable Product",
          "type": "DRUG"
        },
        {
          "name": "Oxycodone Hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Hycet 7.5Mg-325Mg/15Ml Solution",
          "type": "DRUG"
        },
        {
          "name": "Zofran Injection",
          "type": "DRUG"
        },
        {
          "name": "Scopolamine patch",
          "type": "DRUG"
        },
        {
          "name": "Ativan",
          "type": "DRUG"
        },
        {
          "name": "Flexeril Oral Product",
          "type": "DRUG"
        },
        {
          "name": "Tylenol Suspension",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 65 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2021-01-20",
      "completion_date": "2025-06-24",
      "has_results": false,
      "last_update_posted_date": "2026-09-14",
      "last_synced_at": "2026-10-08T00:46:25.477Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04240626"
    },
    {
      "nct_id": "NCT07146685",
      "title": "Effect of Local Anesthetic Concentration on Rebound Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Rebound Pain",
        "Shoulder Arthroplasty",
        "Interscalene Block"
      ],
      "interventions": [
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2026-05-13",
      "completion_date": "2029-01-28",
      "has_results": false,
      "last_update_posted_date": "2026-09-09",
      "last_synced_at": "2026-10-08T00:46:25.477Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07146685"
    },
    {
      "nct_id": "NCT04814433",
      "title": "Evaluating Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Opioid Pain Medication"
      ],
      "interventions": [
        {
          "name": "Tranexamic acid",
          "type": "DRUG"
        },
        {
          "name": "Aminocaproic acid",
          "type": "DRUG"
        },
        {
          "name": "Recombinant Human Thrombin",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine Hydrochloride with Epinephrine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine Hydrochloride with Epinephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 46,
      "start_date": "2021-03-24",
      "completion_date": "2023-07-10",
      "has_results": true,
      "last_update_posted_date": "2024-06-26",
      "last_synced_at": "2026-10-08T00:46:25.477Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04814433"
    },
    {
      "nct_id": "NCT02922985",
      "title": "Multimodal Pain Management for Cesarean Delivery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Intravenous acetominophen",
          "type": "DRUG"
        },
        {
          "name": "Ketorolac, intramuscular",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine, subcutaneous",
          "type": "DRUG"
        },
        {
          "name": "Normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2016-10",
      "completion_date": "2017-07",
      "has_results": true,
      "last_update_posted_date": "2021-12-06",
      "last_synced_at": "2026-10-08T00:46:25.477Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02922985"
    },
    {
      "nct_id": "NCT01986049",
      "title": "Transversus Abdominis Plane (TAP) Block for Post Caesarian Pain",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Obstetrical Complications From Sedation During Parturition"
      ],
      "interventions": [
        {
          "name": "Bupivicaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York Presbyterian Brooklyn Methodist Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2013-02",
      "completion_date": "2013-08",
      "has_results": false,
      "last_update_posted_date": "2021-10-14",
      "last_synced_at": "2026-10-08T00:46:25.477Z",
      "location_count": 1,
      "location_summary": "Brooklyn, New York",
      "locations": [
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01986049"
    },
    {
      "nct_id": "NCT06252662",
      "title": "Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Liposomal bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "United States Naval Medical Center, Portsmouth",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2024-10-15",
      "completion_date": "2025-10",
      "has_results": false,
      "last_update_posted_date": "2024-11-19",
      "last_synced_at": "2026-10-08T00:46:25.477Z",
      "location_count": 1,
      "location_summary": "Portsmouth, Virginia",
      "locations": [
        {
          "city": "Portsmouth",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06252662"
    },
    {
      "nct_id": "NCT01505374",
      "title": "Saphenous Nerve Block vs. Femoral Nerve Block for Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Difference Between Femoral Nerve Block and Saphenous Block"
      ],
      "interventions": [
        {
          "name": "Study Technique",
          "type": "PROCEDURE"
        },
        {
          "name": "Control Technique",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2012-03",
      "completion_date": "2013-09",
      "has_results": true,
      "last_update_posted_date": "2022-04-14",
      "last_synced_at": "2026-10-08T00:46:25.477Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01505374"
    },
    {
      "nct_id": "NCT07276906",
      "title": "Comparing Intramuscular Fentanyl and Ketorolac With Nerve of Arnold (NOA) Block for Bilateral Myringotomy",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "Fentanyl",
          "type": "DRUG"
        },
        {
          "name": "Ketorolac",
          "type": "DRUG"
        },
        {
          "name": "Nerve of Arnold Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham Intramuscular Injection",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham Nerve of Arnold Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of South Alabama",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "6 Months to 6 Years"
      },
      "enrollment_count": 300,
      "start_date": "2026-01",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2025-12-11",
      "last_synced_at": "2026-10-08T00:46:25.477Z",
      "location_count": 1,
      "location_summary": "Mobile, Alabama",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07276906"
    },
    {
      "nct_id": "NCT03103100",
      "title": "Comparing Bupivacaine, Lidocaine, and a Combination of Bupivacaine and Lidocaine for Labor Epidural Activation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Labor Pain"
      ],
      "interventions": [
        {
          "name": "1% Lidocaine",
          "type": "DRUG"
        },
        {
          "name": "0.25% Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine plus Lidocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "19 Years to 60 Years · Female only"
      },
      "enrollment_count": 75,
      "start_date": "2015-10-08",
      "completion_date": "2019-09-09",
      "has_results": true,
      "last_update_posted_date": "2020-08-31",
      "last_synced_at": "2026-10-08T00:46:25.477Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03103100"
    },
    {
      "nct_id": "NCT02933814",
      "title": "Liposomal Bupivacaine in Ambulatory Hand Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Liposomal Bupivicaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2018-02-09",
      "completion_date": "2019-02",
      "has_results": false,
      "last_update_posted_date": "2019-08-07",
      "last_synced_at": "2026-10-08T00:46:25.477Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02933814"
    }
  ]
}