{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine+HCI+%28Marcaine%29", "query": { "intervention": "Bupivacaine HCI (Marcaine)" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-07T08:46:07.148Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02689258", "title": "Evaluation of the Efficacy and Safety of HTX-011 for Postoperative Analgesia Following Abdominoplasty Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "HTX-011B", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "HTX-011A", "type": "DRUG" }, { "name": "HTX-002", "type": "DRUG" }, { "name": "Bupivicaine HCl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Heron Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 277, "start_date": "2016-02-23", "completion_date": "2017-04", "has_results": true, "last_update_posted_date": "2026-03-02", "last_synced_at": "2026-10-07T08:46:07.148Z", "location_count": 8, "location_summary": "Phoenix, Arizona • Pasadena, California • Pasadena, Maryland + 3 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Pasadena", "state": "California" }, { "city": "Pasadena", "state": "Maryland" }, { "city": "Bellaire", "state": "Texas" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02689258" }, { "nct_id": "NCT04787731", "title": "Efficacy of Two Local Anesthetics on Quality of Life After Endodontic Treatment", "overall_status": "SUSPENDED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain, Postoperative", "Quality of Life" ], "interventions": [ { "name": "Bupivacaine Local Anesthetic", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NYU College of Dentistry", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 100, "start_date": "2019-07-29", "completion_date": "2024-10-01", "has_results": false, "last_update_posted_date": "2023-11-08", "last_synced_at": "2026-10-07T08:46:07.148Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04787731" }, { "nct_id": "NCT02762929", "title": "Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Postoperative Pain", "Bunions" ], "interventions": [ { "name": "HTX-011A", "type": "DRUG" }, { "name": "Saline Placebo", "type": "BIOLOGICAL" }, { "name": "HTX-011B", "type": "DRUG" }, { "name": "HTX-002", "type": "DRUG" }, { "name": "Bupivacaine HCl", "type": "DRUG" }, { "name": "HTX-009", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BIOLOGICAL" ], "sponsor": "Heron Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 430, "start_date": "2016-05", "completion_date": "2017-03", "has_results": true, "last_update_posted_date": "2026-02-23", "last_synced_at": "2026-10-07T08:46:07.148Z", "location_count": 5, "location_summary": "Anaheim, California • Bakersfield, California • Pasadena, Maryland + 2 more", "locations": [ { "city": "Anaheim", "state": "California" }, { "city": "Bakersfield", "state": "California" }, { "city": "Pasadena", "state": "Maryland" }, { "city": "Houston", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02762929" }, { "nct_id": "NCT03237481", "title": "Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "HTX-011", "type": "DRUG" }, { "name": "Bupivacaine HCl", "type": "DRUG" }, { "name": "Saline placebo", "type": "DRUG" }, { "name": "Luer-lock applicator", "type": "DEVICE" }, { "name": "Vial access device", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Heron Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 418, "start_date": "2017-07-31", "completion_date": "2018-01-16", "has_results": true, "last_update_posted_date": "2026-03-02", "last_synced_at": "2026-10-07T08:46:07.148Z", "location_count": 22, "location_summary": "Florence, Alabama • Sheffield, Alabama • Phoenix, Arizona + 18 more", "locations": [ { "city": "Florence", "state": "Alabama" }, { "city": "Sheffield", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Bakersfield", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03237481" }, { "nct_id": "NCT03705065", "title": "Bupivacaine HCl PK and Safety in Augmentation Mammoplasty", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Analgesia" ], "interventions": [ { "name": "Bupivacaine HCl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Heron Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 30, "start_date": "2018-09-19", "completion_date": "2018-11-05", "has_results": false, "last_update_posted_date": "2018-12-07", "last_synced_at": "2026-10-07T08:46:07.148Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03705065" }, { "nct_id": "NCT03295721", "title": "Bunionectomy Study for Postoperative Analgesia (EPOCH 1)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "HTX-011", "type": "DRUG" }, { "name": "Saline Placebo", "type": "DRUG" }, { "name": "Bupivacaine HCl", "type": "DRUG" }, { "name": "Luer-lock applicator", "type": "DEVICE" }, { "name": "Vial access device", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Heron Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 412, "start_date": "2017-10-24", "completion_date": "2018-03-13", "has_results": true, "last_update_posted_date": "2026-03-02", "last_synced_at": "2026-10-07T08:46:07.148Z", "location_count": 15, "location_summary": "Mobile, Alabama • Mesa, Arizona • Phoenix, Arizona + 11 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Bakersfield", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03295721" }, { "nct_id": "NCT02504580", "title": "Pilot Herniorrhaphy Study for Postoperative Analgesia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "HTX-011", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "HTX-002", "type": "DRUG" }, { "name": "Bupivacaine HCI (Marcaine)", "type": "DRUG" }, { "name": "HTX-011A", "type": "DRUG" }, { "name": "HTX-011B", "type": "DRUG" }, { "name": "HTX-009", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Heron Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 463, "start_date": "2015-07", "completion_date": "2017-04", "has_results": true, "last_update_posted_date": "2026-03-02", "last_synced_at": "2026-10-07T08:46:07.148Z", "location_count": 3, "location_summary": "Anaheim, California • Houston, Texas", "locations": [ { "city": "Anaheim", "state": "California" }, { "city": "Houston", "state": "Texas" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02504580" }, { "nct_id": "NCT03731221", "title": "Pectoral Fascial Plane and Serratus Anterior Plane Blocks With Bupivacaine v. Liposomal Bupivacaine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Video Assisted Thoracic Surgery" ], "interventions": [ { "name": "Bupi HCI and lipo bupi", "type": "DRUG" }, { "name": "Bupi HCI", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 196, "start_date": "2018-11-01", "completion_date": "2024-09-19", "has_results": false, "last_update_posted_date": "2025-06-10", "last_synced_at": "2026-10-07T08:46:07.148Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT03731221" }, { "nct_id": "NCT03015532", "title": "Total Knee Arthroplasty Infiltration Study for Postoperative Analgesia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "HTX-011", "type": "DRUG" }, { "name": "Saline Placebo", "type": "DRUG" }, { "name": "Bupivicaine HCl", "type": "DRUG" }, { "name": "Ropivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Heron Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 285, "start_date": "2017-01-13", "completion_date": "2018-05-16", "has_results": true, "last_update_posted_date": "2026-03-02", "last_synced_at": "2026-10-07T08:46:07.148Z", "location_count": 24, "location_summary": "Mobile, Alabama • Sheffield, Alabama • Phoenix, Arizona + 13 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Sheffield", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03015532" }, { "nct_id": "NCT04911062", "title": "HTX-011 in Spinal Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Post-Operative Pain", "Lumbar Laminectomy" ], "interventions": [ { "name": "Bupivacaine HCI without epinephrine", "type": "DRUG" }, { "name": "HTX-011", "type": "DRUG" }, { "name": "Luer Lock Applicator", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Heron Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 32, "start_date": "2022-04-07", "completion_date": "2022-08-26", "has_results": false, "last_update_posted_date": "2023-06-12", "last_synced_at": "2026-10-07T08:46:07.148Z", "location_count": 12, "location_summary": "Phoenix, Arizona • Pasadena, California • Wichita, Kansas + 9 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Pasadena", "state": "California" }, { "city": "Wichita", "state": "Kansas" }, { "city": "Shreveport", "state": "Louisiana" }, { "city": "Summit", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT04911062" } ] }