{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine+HCL&page=20",
    "query": {
      "intervention": "Bupivacaine HCL",
      "page": 20
    },
    "page_size": 10
  },
  "pagination": {
    "page": 20,
    "page_size": 10,
    "total_count": 951,
    "total_pages": 96,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine+HCL&page=21&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine+HCL&page=19&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-14T08:28:51.204Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05094427",
      "title": "Perioperative Local Anesthesia Block in Spine Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lumbar Spine Disease",
        "Lumbar Disc Herniation",
        "Lumbar Spinal Stenosis"
      ],
      "interventions": [
        {
          "name": "Preoperative fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 232,
      "start_date": "2021-03-10",
      "completion_date": "2022-03-31",
      "has_results": false,
      "last_update_posted_date": "2022-09-13",
      "last_synced_at": "2026-10-14T08:28:51.204Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05094427"
    },
    {
      "nct_id": "NCT02674113",
      "title": "Regional Anesthesia in Hip Arthroscopy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Femoroacetabular Impingement"
      ],
      "interventions": [
        {
          "name": "regional anesthesia bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "regional anesthesia placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 0,
      "start_date": "2015-10",
      "completion_date": "2017-10",
      "has_results": false,
      "last_update_posted_date": "2017-02-10",
      "last_synced_at": "2026-10-14T08:28:51.204Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02674113"
    },
    {
      "nct_id": "NCT06471348",
      "title": "Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post Operative Pain",
        "Spinal Fusion"
      ],
      "interventions": [
        {
          "name": "Bupivacaine liposome injectable suspension",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine Hydrochloride and Epinephrine Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "10 Years to 17 Years"
      },
      "enrollment_count": 128,
      "start_date": "2025-08-15",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-22",
      "last_synced_at": "2026-10-14T08:28:51.204Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06471348"
    },
    {
      "nct_id": "NCT05521789",
      "title": "Erector Spinae Block for Thoracic Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pulmonary Neoplasm",
        "Pulmonary Cancer",
        "Thoracic Diseases",
        "Thoracic Cancer",
        "Thoracic Neoplasms"
      ],
      "interventions": [
        {
          "name": "ESB Thoracic",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "George Washington University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 70,
      "start_date": "2022-07-22",
      "completion_date": "2027-07-21",
      "has_results": false,
      "last_update_posted_date": "2026-02-25",
      "last_synced_at": "2026-10-14T08:28:51.204Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05521789"
    },
    {
      "nct_id": "NCT02803450",
      "title": "Epidural Loading: High Volume, Low Concentration",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Labor and Delivery"
      ],
      "interventions": [
        {
          "name": "Epidural needle",
          "type": "PROCEDURE"
        },
        {
          "name": "Catheter Administration",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard of Care Epidural Administration",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 89 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2016-02",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2021-09-27",
      "last_synced_at": "2026-10-14T08:28:51.204Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02803450"
    },
    {
      "nct_id": "NCT02008591",
      "title": "Comparison of Epidural Labor Pain Relief Techniques on Maternal and Fetal Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Laboring Women Requesting Neuraxial Labor Analgesia"
      ],
      "interventions": [
        {
          "name": "Epidural Technique versus Dural Puncture Epidural Technique versus Combined Spinal Epidural Technique",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2013-11-26",
      "completion_date": "2016-01-27",
      "has_results": false,
      "last_update_posted_date": "2017-01-24",
      "last_synced_at": "2026-10-14T08:28:51.204Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02008591"
    },
    {
      "nct_id": "NCT04254692",
      "title": "Optimizing Recovery in Abdominoplasty",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "Liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Standard of care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2021-01-05",
      "completion_date": "2021-01-21",
      "has_results": true,
      "last_update_posted_date": "2024-08-07",
      "last_synced_at": "2026-10-14T08:28:51.204Z",
      "location_count": 2,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04254692"
    },
    {
      "nct_id": "NCT01586806",
      "title": "Comparing Subsartorial Saphenous Nerve Blocks With and Without Dexamethasone for Anterior Cruciate Ligament Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Reconstruction",
        "Regional Anesthesia, Saphenous Nerve Block"
      ],
      "interventions": [
        {
          "name": "Bupivacaine Only",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine with 1 mg of Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine with 4 mg of Dexamethasone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "16 Years to 65 Years"
      },
      "enrollment_count": 195,
      "start_date": "2012-07",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2016-11-28",
      "last_synced_at": "2026-10-14T08:28:51.204Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01586806"
    },
    {
      "nct_id": "NCT02980926",
      "title": "Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anesthesia, Spinal",
        "Arthroplasty, Replacement, Knee",
        "Pain Management",
        "Early Ambulation",
        "Ambulatory Surgical Procedures"
      ],
      "interventions": [
        {
          "name": "Mepivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "40 Years to 90 Years"
      },
      "enrollment_count": 32,
      "start_date": "2016-12",
      "completion_date": "2017-03",
      "has_results": false,
      "last_update_posted_date": "2017-03-27",
      "last_synced_at": "2026-10-14T08:28:51.204Z",
      "location_count": 1,
      "location_summary": "West Bloomfield, Michigan",
      "locations": [
        {
          "city": "West Bloomfield",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02980926"
    },
    {
      "nct_id": "NCT03581539",
      "title": "Comparing 3 Different Types of Pain Blocks After Laparoscopic Nephrectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nephrectomy"
      ],
      "interventions": [
        {
          "name": "Transverses Abdominis Plane (TAP) block",
          "type": "PROCEDURE"
        },
        {
          "name": "Quadratus Lumborum (QL) block",
          "type": "PROCEDURE"
        },
        {
          "name": "Surgeon Infiltration using Exparel",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2018-05-22",
      "completion_date": "2020-11-17",
      "has_results": false,
      "last_update_posted_date": "2023-06-27",
      "last_synced_at": "2026-10-14T08:28:51.204Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03581539"
    }
  ]
}