{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine+Hydrochloride&page=19", "query": { "intervention": "Bupivacaine Hydrochloride", "page": 19 }, "page_size": 10 }, "pagination": { "page": 19, "page_size": 10, "total_count": 951, "total_pages": 96, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine+Hydrochloride&page=20&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine+Hydrochloride&page=18&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-14T05:06:08.585Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04908449", "title": "Pectointercostal Fascial Plane Block (PIFB) Alone Versus PIFB With Rectus Sheath Block (RSB) in Cardiac Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Coronary Artery Disease", "Postoperative Pain", "Respiratory Failure" ], "interventions": [ { "name": "Rectus sheath block with bupivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Medical College of Wisconsin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 62, "start_date": "2023-06-19", "completion_date": "2024-11-14", "has_results": true, "last_update_posted_date": "2025-11-17", "last_synced_at": "2026-10-14T05:06:08.585Z", "location_count": 1, "location_summary": "Milwaukee, Wisconsin", "locations": [ { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT04908449" }, { "nct_id": "NCT04180943", "title": "Liposomal Bupivacaine Versus Bupivacaine for for Postoperative Pain Control in Shoulder Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Anesthesia, Local" ], "interventions": [ { "name": "interscalene nerve block", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bassett Healthcare", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 85, "start_date": "2019-12-13", "completion_date": "2021-06-01", "has_results": false, "last_update_posted_date": "2022-03-02", "last_synced_at": "2026-10-14T05:06:08.585Z", "location_count": 1, "location_summary": "Cooperstown, New York", "locations": [ { "city": "Cooperstown", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04180943" }, { "nct_id": "NCT02280291", "title": "Single Shot Versus OnQ Pump in Extremity Fractures", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain", "Fracture" ], "interventions": [ { "name": "Ankle SSB", "type": "DRUG" }, { "name": "Ankle OnQ", "type": "DRUG" }, { "name": "DR SSB", "type": "DRUG" }, { "name": "DR OnQ", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NYU Langone Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 100, "start_date": "2013-08", "completion_date": "2018-12-13", "has_results": true, "last_update_posted_date": "2020-03-30", "last_synced_at": "2026-10-14T05:06:08.585Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02280291" }, { "nct_id": "NCT02726620", "title": "Decision Support for Intraoperative Low Blood Pressure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypotension" ], "interventions": [ { "name": "Attending real-time decision support", "type": "PROCEDURE" }, { "name": "In-room real-time decision support", "type": "PROCEDURE" }, { "name": "Attending feedback emails", "type": "PROCEDURE" }, { "name": "In-room provider feedback emails", "type": "PROCEDURE" }, { "name": "Anesthesia Information Management System (AIMS)", "type": "DEVICE" }, { "name": "Perioperative Data Warehouse (PDW)", "type": "DEVICE" }, { "name": "General anesthesia", "type": "PROCEDURE" }, { "name": "Pager system", "type": "DEVICE" }, { "name": "Central neuraxial anesthesia", "type": "PROCEDURE" }, { "name": "Non-cardiac surgery", "type": "PROCEDURE" }, { "name": "Propofol", "type": "DRUG" }, { "name": "Sevoflurane", "type": "DRUG" }, { "name": "Desflurane", "type": "DRUG" }, { "name": "Isoflurane", "type": "DRUG" }, { "name": "Ephedrine", "type": "DRUG" }, { "name": "Phenylephrine", "type": "DRUG" }, { "name": "Norepinephrine", "type": "DRUG" }, { "name": "Epinephrine", "type": "DRUG" }, { "name": "Dobutamine", "type": "DRUG" }, { "name": "Dopamine", "type": "DRUG" }, { "name": "Isoproterenol", "type": "DRUG" }, { "name": "Milrinone", "type": "DRUG" }, { "name": "Atropine", "type": "DRUG" }, { "name": "Glycopyrrolate", "type": "DRUG" }, { "name": "Vasopressin", "type": "DRUG" }, { "name": "Terlipressin", "type": "DRUG" }, { "name": "Sodium Chloride 0.9%", "type": "DRUG" }, { "name": "Ringer's lactate", "type": "DRUG" }, { "name": "Hydroxyethyl starch solutions", "type": "DRUG" }, { "name": "Fresh Frozen Plasma", "type": "DRUG" }, { "name": "Packed Red Blood Cells", "type": "DRUG" }, { "name": "Albumin solutions", "type": "DRUG" }, { "name": "Plasma-Lyte", "type": "DRUG" }, { "name": "Lidocaine", "type": "DRUG" }, { "name": "Bupivacaine", "type": "DRUG" }, { "name": "Levobupivacaine", "type": "DRUG" }, { "name": "Ropivacaine", "type": "DRUG" }, { "name": "Mepivacaine", "type": "DRUG" }, { "name": "Tetracaine", "type": "DRUG" }, { "name": "Prilocaine", "type": "DRUG" }, { "name": "Procaine", "type": "DRUG" }, { "name": "Chloroprocaine", "type": "DRUG" }, { "name": "Benzocaine", "type": "DRUG" }, { "name": "Articaine", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DEVICE", "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "60 Years to 100 Years" }, "enrollment_count": 22435, "start_date": "2017-01-05", "completion_date": "2018-12-29", "has_results": true, "last_update_posted_date": "2019-05-16", "last_synced_at": "2026-10-14T05:06:08.585Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02726620" }, { "nct_id": "NCT00678379", "title": "Pediatric Tonsillectomy Pain Reduction Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "lidocaine (1%) + bupivacaine (0.5%)", "type": "DRUG" }, { "name": "Normal saline", "type": "DRUG" }, { "name": "Lidocaine (1%) + Bupivacaine (0.5%) + Clonidine (25mcg)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "3 Years to 17 Years" }, "enrollment_count": 120, "start_date": "2008-04", "completion_date": "2009-11", "has_results": true, "last_update_posted_date": "2017-07-02", "last_synced_at": "2026-10-14T05:06:08.585Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00678379" }, { "nct_id": "NCT03219983", "title": "Pain Management After Total Shoulder Arthroplasty", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Glenohumeral Arthritis", "Total Shoulder Arthroplasty" ], "interventions": [ { "name": "Ropivacaine", "type": "DRUG" }, { "name": "liposomal bupivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Christ Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 22, "start_date": "2016-11", "completion_date": "2017-09", "has_results": false, "last_update_posted_date": "2017-11-06", "last_synced_at": "2026-10-14T05:06:08.585Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT03219983" }, { "nct_id": "NCT02679560", "title": "Effects of Liposomal Bupivacaine for Acute Pain in Hip and Femur Fractures", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Femoral Fractures" ], "interventions": [ { "name": "Liposomal Bupivacaine", "type": "DRUG" }, { "name": "Ropivacaine HCL", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ian Elliott Brown", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 3, "start_date": "2017-10-01", "completion_date": "2019-11-01", "has_results": true, "last_update_posted_date": "2021-02-21", "last_synced_at": "2026-10-14T05:06:08.585Z", "location_count": 1, "location_summary": "Sacramento, California", "locations": [ { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02679560" }, { "nct_id": "NCT03853694", "title": "Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Undergoing Elective Cesarean Section", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Elective Cesarean Section", "Pain Management" ], "interventions": [ { "name": "50 mcg Duramorph+ EXPAREL + multi-modal pain regimen", "type": "DRUG" }, { "name": "150 mcg Duramorph + multi-modal pain regimen", "type": "DRUG" }, { "name": "Exparel TAP + multi-modal pain regimen", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pacira Pharmaceuticals, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 167, "start_date": "2019-03-04", "completion_date": "2020-01-16", "has_results": true, "last_update_posted_date": "2022-07-18", "last_synced_at": "2026-10-14T05:06:08.585Z", "location_count": 18, "location_summary": "Stanford, California • Gainesville, Florida • Jacksonville, Florida + 13 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Idaho Falls", "state": "Idaho" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT03853694" }, { "nct_id": "NCT04704297", "title": "Trigger Point Injection for Myofascial Pain Syndrome in the Low Back: A Randomized Controlled Trial", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Low Back Pain", "Myofascial Pain Syndrome Lower Back" ], "interventions": [ { "name": "Treatment of Myofascial Pain Syndrome in the low back. This intervention will be based on outcomes of the medications listed below.", "type": "DRUG" }, { "name": "Evaluation of functional ability using a patient centered functional score known as the Modified Oswestry Disability Index (MODI). The intervention will be based on outcomes of medications below.", "type": "DRUG" }, { "name": "Following up with participants 60-72 hours after treatment in the Emergency Department. This intervention will be based on outcomes of the medications listed below.", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Madigan Army Medical Center", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 180, "start_date": "2020-12-28", "completion_date": "2022-07-01", "has_results": false, "last_update_posted_date": "2021-01-12", "last_synced_at": "2026-10-14T05:06:08.585Z", "location_count": 1, "location_summary": "Tacoma, Washington", "locations": [ { "city": "Tacoma", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT04704297" }, { "nct_id": "NCT00979342", "title": "Comparative Sedation Study of the MyoSure Hysteroscopic Tissue Removal System", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Uterine Fibroids", "Polyps" ], "interventions": [ { "name": "Hysteroscopic Morcellator", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Hologic, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "FEMALE", "summary": "18 Years to 65 Years · Female only" }, "enrollment_count": 40, "start_date": "2009-11", "completion_date": "2010-07", "has_results": false, "last_update_posted_date": "2010-07-23", "last_synced_at": "2026-10-14T05:06:08.585Z", "location_count": 5, "location_summary": "Phoenix, Arizona • Boca Raton, Florida • Detroit, Michigan + 2 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Boca Raton", "state": "Florida" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Edina", "state": "Minnesota" }, { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00979342" } ] }