{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine+Hydrochloride-EPINEPHrine", "query": { "intervention": "Bupivacaine Hydrochloride-EPINEPHrine" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 181, "total_pages": 19, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivacaine+Hydrochloride-EPINEPHrine&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-06T00:40:11.263Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06069154", "title": "Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Pain Following Thoracic Trauma", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Rib Fracture", "Rib Fracture Multiple" ], "interventions": [ { "name": "Cryoneurolysis", "type": "DEVICE" }, { "name": "Local anesthetic peripheral nerve block", "type": "PROCEDURE" }, { "name": "Sham Cryoneurolysis", "type": "DEVICE" }, { "name": "Sham peripheral nerve block", "type": "PROCEDURE" } ], "intervention_types": [ "DEVICE", "PROCEDURE" ], "sponsor": "University of California, San Diego", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 120, "start_date": "2023-10-30", "completion_date": "2028-12", "has_results": false, "last_update_posted_date": "2026-08-24", "last_synced_at": "2026-10-06T00:40:11.263Z", "location_count": 5, "location_summary": "La Jolla, California • Bethesda, Maryland • Boston, Massachusetts + 1 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Bethesda", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06069154" }, { "nct_id": "NCT07276906", "title": "Comparing Intramuscular Fentanyl and Ketorolac With Nerve of Arnold (NOA) Block for Bilateral Myringotomy", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "Fentanyl", "type": "DRUG" }, { "name": "Ketorolac", "type": "DRUG" }, { "name": "Nerve of Arnold Block", "type": "PROCEDURE" }, { "name": "Sham Intramuscular Injection", "type": "PROCEDURE" }, { "name": "Sham Nerve of Arnold Block", "type": "PROCEDURE" }, { "name": "Dexmedetomidine", "type": "DRUG" }, { "name": "Bupivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of South Alabama", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "6 Years", "sex": "ALL", "summary": "6 Months to 6 Years" }, "enrollment_count": 300, "start_date": "2026-01", "completion_date": "2026-08", "has_results": false, "last_update_posted_date": "2025-12-11", "last_synced_at": "2026-10-06T00:40:11.263Z", "location_count": 1, "location_summary": "Mobile, Alabama", "locations": [ { "city": "Mobile", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT07276906" }, { "nct_id": "NCT05118620", "title": "Pericapsular Nerve Group Block (PENG) for Hip Surgery", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hip Arthropathy", "Postoperative Pain, Acute", "Pain, Postoperative" ], "interventions": [ { "name": "Active bupivacaine 0.375% PENG block", "type": "DRUG" }, { "name": "Placebo normal saline PENG block", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Diego", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2021-12-09", "completion_date": "2022-05-31", "has_results": false, "last_update_posted_date": "2022-06-03", "last_synced_at": "2026-10-06T00:40:11.263Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05118620" }, { "nct_id": "NCT04735185", "title": "Stem Cells vs. Steroids for Discogenic Back Pain", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Chronic Low Back Pain", "Degenerative Disc Disease" ], "interventions": [ { "name": "Autologous stem cells", "type": "OTHER" }, { "name": "Corticosteroid", "type": "DRUG" }, { "name": "Local anesthetic", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 0, "start_date": "2025-09-30", "completion_date": "2028-11-30", "has_results": false, "last_update_posted_date": "2025-10-07", "last_synced_at": "2026-10-06T00:40:11.263Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT04735185" }, { "nct_id": "NCT06120530", "title": "Intraperitoneal Bupivacaine for Pelvic Organ Prolapse", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pelvic Organ Prolapse" ], "interventions": [ { "name": "Bupivacaine", "type": "DRUG" }, { "name": "Saline", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "FEMALE", "summary": "18 Years to 90 Years · Female only" }, "enrollment_count": 91, "start_date": "2023-08-16", "completion_date": "2024-03-15", "has_results": true, "last_update_posted_date": "2025-04-20", "last_synced_at": "2026-10-06T00:40:11.263Z", "location_count": 1, "location_summary": "Carmel, Indiana", "locations": [ { "city": "Carmel", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT06120530" }, { "nct_id": "NCT03906617", "title": "Bupivacaine/Epinephrine +Dexamethasone vs. Liposomal Bupivacaine", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Robotic Lung Surgery" ], "interventions": [ { "name": "Intercostal nerve block and wound infiltration with liposomal bupivacaine", "type": "DRUG" }, { "name": "Intercostal nerve block and wound infiltration with bupivacaine/epinephrine + dexamethasone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Cooper Health System", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 34, "start_date": "2019-04-10", "completion_date": "2022-06-10", "has_results": false, "last_update_posted_date": "2021-11-12", "last_synced_at": "2026-10-06T00:40:11.263Z", "location_count": 1, "location_summary": "Camden, New Jersey", "locations": [ { "city": "Camden", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT03906617" }, { "nct_id": "NCT06547255", "title": "Exparel Versus Bupivacaine in Post-operative Pain Control", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Liposomal Bupivacaine" ], "interventions": [ { "name": "Bupivacaine liposome injectable suspension", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Case Western Reserve University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 100, "start_date": "2024-08-21", "completion_date": "2025-07-01", "has_results": true, "last_update_posted_date": "2026-07-28", "last_synced_at": "2026-10-06T00:40:11.263Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT06547255" }, { "nct_id": "NCT07213635", "title": "Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Opioid Use", "Surgical Recovery", "Vaginal Hysterectomy", "Prolapse Pelvic", "Postoperative Pain" ], "interventions": [ { "name": "Bupivacaine-epinephrine", "type": "DRUG" }, { "name": "Normal saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of North Carolina, Chapel Hill", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 50, "start_date": "2025-10-20", "completion_date": "2026-09-24", "has_results": false, "last_update_posted_date": "2026-10-02", "last_synced_at": "2026-10-06T00:40:11.263Z", "location_count": 1, "location_summary": "Raleigh, North Carolina", "locations": [ { "city": "Raleigh", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT07213635" }, { "nct_id": "NCT00645138", "title": "Comparison of Paravertebral Block With General Anesthesia in Patients Undergoing Breast Cancer Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Breast Cancer" ], "interventions": [ { "name": "Paravertebral Block", "type": "PROCEDURE" }, { "name": "General Anesthesia", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Weill Medical College of Cornell University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 40, "start_date": "2008-04", "completion_date": "2010-03", "has_results": false, "last_update_posted_date": "2011-08-05", "last_synced_at": "2026-10-06T00:40:11.263Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00645138" }, { "nct_id": "NCT02726620", "title": "Decision Support for Intraoperative Low Blood Pressure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypotension" ], "interventions": [ { "name": "Attending real-time decision support", "type": "PROCEDURE" }, { "name": "In-room real-time decision support", "type": "PROCEDURE" }, { "name": "Attending feedback emails", "type": "PROCEDURE" }, { "name": "In-room provider feedback emails", "type": "PROCEDURE" }, { "name": "Anesthesia Information Management System (AIMS)", "type": "DEVICE" }, { "name": "Perioperative Data Warehouse (PDW)", "type": "DEVICE" }, { "name": "General anesthesia", "type": "PROCEDURE" }, { "name": "Pager system", "type": "DEVICE" }, { "name": "Central neuraxial anesthesia", "type": "PROCEDURE" }, { "name": "Non-cardiac surgery", "type": "PROCEDURE" }, { "name": "Propofol", "type": "DRUG" }, { "name": "Sevoflurane", "type": "DRUG" }, { "name": "Desflurane", "type": "DRUG" }, { "name": "Isoflurane", "type": "DRUG" }, { "name": "Ephedrine", "type": "DRUG" }, { "name": "Phenylephrine", "type": "DRUG" }, { "name": "Norepinephrine", "type": "DRUG" }, { "name": "Epinephrine", "type": "DRUG" }, { "name": "Dobutamine", "type": "DRUG" }, { "name": "Dopamine", "type": "DRUG" }, { "name": "Isoproterenol", "type": "DRUG" }, { "name": "Milrinone", "type": "DRUG" }, { "name": "Atropine", "type": "DRUG" }, { "name": "Glycopyrrolate", "type": "DRUG" }, { "name": "Vasopressin", "type": "DRUG" }, { "name": "Terlipressin", "type": "DRUG" }, { "name": "Sodium Chloride 0.9%", "type": "DRUG" }, { "name": "Ringer's lactate", "type": "DRUG" }, { "name": "Hydroxyethyl starch solutions", "type": "DRUG" }, { "name": "Fresh Frozen Plasma", "type": "DRUG" }, { "name": "Packed Red Blood Cells", "type": "DRUG" }, { "name": "Albumin solutions", "type": "DRUG" }, { "name": "Plasma-Lyte", "type": "DRUG" }, { "name": "Lidocaine", "type": "DRUG" }, { "name": "Bupivacaine", "type": "DRUG" }, { "name": "Levobupivacaine", "type": "DRUG" }, { "name": "Ropivacaine", "type": "DRUG" }, { "name": "Mepivacaine", "type": "DRUG" }, { "name": "Tetracaine", "type": "DRUG" }, { "name": "Prilocaine", "type": "DRUG" }, { "name": "Procaine", "type": "DRUG" }, { "name": "Chloroprocaine", "type": "DRUG" }, { "name": "Benzocaine", "type": "DRUG" }, { "name": "Articaine", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DEVICE", "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "60 Years to 100 Years" }, "enrollment_count": 22435, "start_date": "2017-01-05", "completion_date": "2018-12-29", "has_results": true, "last_update_posted_date": "2019-05-16", "last_synced_at": "2026-10-06T00:40:11.263Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02726620" } ] }