{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivicaine+%28local+anesthesia+injection%29",
    "query": {
      "intervention": "Bupivicaine (local anesthesia injection)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 27,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupivicaine+%28local+anesthesia+injection%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-07T14:14:04.220Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05972681",
      "title": "The PAIN (Pelvic Area Injection for Numbness) Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Vaginal Laceration During Delivery"
      ],
      "interventions": [
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Epinephrine",
          "type": "DRUG"
        },
        {
          "name": "Sham normal saline arm",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 3,
      "start_date": "2025-04-08",
      "completion_date": "2025-10-19",
      "has_results": true,
      "last_update_posted_date": "2026-05-27",
      "last_synced_at": "2026-10-07T14:14:04.220Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05972681"
    },
    {
      "nct_id": "NCT06989866",
      "title": "RCT to Test Regional Anesthesia Effect on Decreased Opiate Use",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Saline (NaCl 0,9 %) (placebo)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "United States Naval Medical Center, Portsmouth",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2024-12-01",
      "completion_date": "2026-09-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-09",
      "last_synced_at": "2026-10-07T14:14:04.220Z",
      "location_count": 1,
      "location_summary": "Portsmouth, Virginia",
      "locations": [
        {
          "city": "Portsmouth",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06989866"
    },
    {
      "nct_id": "NCT03887650",
      "title": "LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Post-operative Pain",
        "Total Shoulder Arthroplasty",
        "Osteoarthritis of the Shoulder",
        "Pain Management"
      ],
      "interventions": [
        {
          "name": "Liposomal Bupivicaine 1.3%",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine 0.5%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hartford Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 90,
      "start_date": "2019-03-11",
      "completion_date": "2022-03-08",
      "has_results": true,
      "last_update_posted_date": "2023-09-15",
      "last_synced_at": "2026-10-07T14:14:04.220Z",
      "location_count": 1,
      "location_summary": "Hartford, Connecticut",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03887650"
    },
    {
      "nct_id": "NCT03043027",
      "title": "Efficacy of Liposomal Bupivacaine for Pain Control After Percutaneous Nephrostolithotomy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Renal Calculi",
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "liposomal bupivicaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Saline Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 0,
      "start_date": "2017-08-08",
      "completion_date": "2017-08-08",
      "has_results": false,
      "last_update_posted_date": "2017-08-28",
      "last_synced_at": "2026-10-07T14:14:04.220Z",
      "location_count": 1,
      "location_summary": "Manhasset, New York",
      "locations": [
        {
          "city": "Manhasset",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03043027"
    },
    {
      "nct_id": "NCT00398866",
      "title": "A Study of Hyaluronan for the Treatment of Osteoarthritis in the Thumb",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Synvisc (Hylan G-F20; hyaluronan injection)",
          "type": "DRUG"
        },
        {
          "name": "Bupivicaine (local anesthesia injection)",
          "type": "DRUG"
        },
        {
          "name": "Kenalog (triamcinolone; corticosteroid injection)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "45 Years to 95 Years"
      },
      "enrollment_count": 200,
      "start_date": "2006-08",
      "completion_date": "2013-03",
      "has_results": true,
      "last_update_posted_date": "2017-07-07",
      "last_synced_at": "2026-10-07T14:14:04.220Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00398866"
    },
    {
      "nct_id": "NCT02473198",
      "title": "Femoral Nerve Block Compared to Exparel in Total Knee Replacement",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Osteoarthritis",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Exparel",
          "type": "DRUG"
        },
        {
          "name": "Femoral Nerve Block Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Toradol",
          "type": "DRUG"
        },
        {
          "name": "Morphine Sulfate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The New England Baptist Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "73 Years",
        "sex": "ALL",
        "summary": "18 Years to 73 Years"
      },
      "enrollment_count": 312,
      "start_date": "2014-01",
      "completion_date": "2017-02",
      "has_results": false,
      "last_update_posted_date": "2016-03-17",
      "last_synced_at": "2026-10-07T14:14:04.220Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02473198"
    },
    {
      "nct_id": "NCT01267825",
      "title": "CT Guided Injection for Low Back Radiculopathy: A Randomized Clinical Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Disc Herniation",
        "Lumbosacral Radiculopathy"
      ],
      "interventions": [
        {
          "name": "CT-guided corticosteroid+ bupivicaine",
          "type": "DRUG"
        },
        {
          "name": "Standard medical care",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 1,
      "start_date": "2010-09-01",
      "completion_date": "2013-08",
      "has_results": true,
      "last_update_posted_date": "2018-08-31",
      "last_synced_at": "2026-10-07T14:14:04.220Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01267825"
    },
    {
      "nct_id": "NCT03574376",
      "title": "Liposomal Bupivacaine Intercostal Nerve Block vs Thoracic Epidural for Regional Analgesia in Multiple Rib Fractures",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Trauma",
        "Trauma Injury",
        "Pain, Acute"
      ],
      "interventions": [
        {
          "name": "Bupivacaine Liposome Injection",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Chadrick Evans",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 258,
      "start_date": "2018-08-29",
      "completion_date": "2021-08-01",
      "has_results": false,
      "last_update_posted_date": "2020-03-09",
      "last_synced_at": "2026-10-07T14:14:04.220Z",
      "location_count": 1,
      "location_summary": "Peoria, Illinois",
      "locations": [
        {
          "city": "Peoria",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03574376"
    },
    {
      "nct_id": "NCT01062087",
      "title": "Pain Perception After Tubal Ligation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Bupivacaine, Lidocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Oklahoma State University Center for Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "52 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 52 Years · Female only"
      },
      "enrollment_count": 62,
      "start_date": "2010-01",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2012-05-03",
      "last_synced_at": "2026-10-07T14:14:04.220Z",
      "location_count": 1,
      "location_summary": "Tulsa, Oklahoma",
      "locations": [
        {
          "city": "Tulsa",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01062087"
    },
    {
      "nct_id": "NCT02052557",
      "title": "The Effect of Exparel on Post Operative Pain and Narcotic Use After Colon Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Post-operative Pain",
        "Colon Cancer",
        "Diverticulitis"
      ],
      "interventions": [
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine liposome suspension",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Des Moines University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2013-02",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2021-01-08",
      "last_synced_at": "2026-10-07T14:14:04.220Z",
      "location_count": 1,
      "location_summary": "Des Moines, Iowa",
      "locations": [
        {
          "city": "Des Moines",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02052557"
    }
  ]
}