{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupropion+%28drug%29&page=3", "query": { "intervention": "Bupropion (drug)", "page": 3 }, "page_size": 10 }, "pagination": { "page": 3, "page_size": 10, "total_count": 340, "total_pages": 34, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupropion+%28drug%29&page=4&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Bupropion+%28drug%29&page=2&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-12T14:03:36.547Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06223880", "title": "A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "AXS-05", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Axsome Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 350, "start_date": "2023-12-27", "completion_date": "2026-03", "has_results": false, "last_update_posted_date": "2025-01-23", "last_synced_at": "2026-10-12T14:03:36.547Z", "location_count": 40, "location_summary": "Bellflower, California • Lafayette, California • Oceanside, California + 34 more", "locations": [ { "city": "Bellflower", "state": "California" }, { "city": "Lafayette", "state": "California" }, { "city": "Oceanside", "state": "California" }, { "city": "Redlands", "state": "California" }, { "city": "Riverside", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06223880" }, { "nct_id": "NCT04464577", "title": "A Study to Evaluate the Effect of Fluconazole, Bupropion, or Itraconazole on the Drug Levels and Safety of BMS-986235", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Participants" ], "interventions": [ { "name": "Fluconazole", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Itraconazole", "type": "DRUG" }, { "name": "BMS-986235", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 0, "start_date": "2021-04-01", "completion_date": "2021-06-08", "has_results": false, "last_update_posted_date": "2022-03-25", "last_synced_at": "2026-10-12T14:03:36.547Z", "location_count": 2, "location_summary": "Lenexa, Kansas • Salt Lake City, Utah", "locations": [ { "city": "Lenexa", "state": "Kansas" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT04464577" }, { "nct_id": "NCT01309217", "title": "Dissemination of Tobacco Tactics for Hospitalized Smokers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Smoking Cessation" ], "interventions": [ { "name": "Tobacco Tactics Intervention", "type": "BEHAVIORAL" }, { "name": "Usual Care", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1528, "start_date": "2011-07", "completion_date": "2014-03", "has_results": false, "last_update_posted_date": "2014-11-18", "last_synced_at": "2026-10-12T14:03:36.547Z", "location_count": 6, "location_summary": "Grand Rapids, Michigan • Livonia, Michigan • Muskegon, Michigan + 2 more", "locations": [ { "city": "Grand Rapids", "state": "Michigan" }, { "city": "Livonia", "state": "Michigan" }, { "city": "Muskegon", "state": "Michigan" }, { "city": "Muskegon", "state": "Michigan" }, { "city": "Oakland", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01309217" }, { "nct_id": "NCT05981365", "title": "Voxelotor CYP and Transporter Cocktail Interaction Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Sickle Cell Disease" ], "interventions": [ { "name": "Voxelotor", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Repaglinide", "type": "DRUG" }, { "name": "Flurbiprofen", "type": "DRUG" }, { "name": "Omeprazole", "type": "DRUG" }, { "name": "Midazolam", "type": "DRUG" }, { "name": "Metformin", "type": "DRUG" }, { "name": "Furosemide", "type": "DRUG" }, { "name": "Rosuvastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 44, "start_date": "2023-04-17", "completion_date": "2023-10-04", "has_results": true, "last_update_posted_date": "2024-11-22", "last_synced_at": "2026-10-12T14:03:36.547Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05981365" }, { "nct_id": "NCT00587769", "title": "Chantix & Bupropion for Smoking Cessation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Smoking", "Tobacco Use Disorder" ], "interventions": [ { "name": "Bupropion SR & Varenicline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 38, "start_date": "2007-07", "completion_date": "2008-07", "has_results": true, "last_update_posted_date": "2013-04-24", "last_synced_at": "2026-10-12T14:03:36.547Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00587769" }, { "nct_id": "NCT03063606", "title": "Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Specialist Treatment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Binge-Eating Disorder", "Obesity" ], "interventions": [ { "name": "Cognitive-Behavioral Therapy (CBT)", "type": "BEHAVIORAL" }, { "name": "NB Medication (on-going from acute treatment)", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 31, "start_date": "2017-09-05", "completion_date": "2022-12-16", "has_results": true, "last_update_posted_date": "2024-02-01", "last_synced_at": "2026-10-12T14:03:36.547Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT03063606" }, { "nct_id": "NCT00104598", "title": "Framing Messages for Smoking Cessation With Bupropion - 6", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tobacco Use Disorder" ], "interventions": [ { "name": "Bupropion", "type": "DRUG" }, { "name": "Smoking Abstinence Program", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 252, "start_date": "2000-09", "completion_date": "2006-12", "has_results": false, "last_update_posted_date": "2013-08-09", "last_synced_at": "2026-10-12T14:03:36.547Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00104598" }, { "nct_id": "NCT04634071", "title": "Tobacco Treatment Optimization and Preferences During Concurrent Cancer Treatment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Smoking Cessation", "Cancer, Treatment-Related" ], "interventions": [ { "name": "Varenicline", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Long-acting nicotine replacement therapy", "type": "DRUG" }, { "name": "Low-intensity counseling", "type": "BEHAVIORAL" }, { "name": "High-intensity counseling", "type": "BEHAVIORAL" }, { "name": "No nicotine replacement therapy", "type": "OTHER" }, { "name": "Nicotine Replacement Products", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BEHAVIORAL", "OTHER" ], "sponsor": "Joseph Valentino, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 126, "start_date": "2021-01-12", "completion_date": "2026-01-02", "has_results": false, "last_update_posted_date": "2026-02-02", "last_synced_at": "2026-10-12T14:03:36.547Z", "location_count": 3, "location_summary": "Bowling Green, Kentucky • Lexington, Kentucky • Owensboro, Kentucky", "locations": [ { "city": "Bowling Green", "state": "Kentucky" }, { "city": "Lexington", "state": "Kentucky" }, { "city": "Owensboro", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT04634071" }, { "nct_id": "NCT00991081", "title": "Behaviorally Enhanced Counseling on Nicotine Dependence (BEACON) Trial.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Smoking" ], "interventions": [ { "name": "Counseling", "type": "BEHAVIORAL" }, { "name": "Self-help guide", "type": "BEHAVIORAL" }, { "name": "Pharmacotherapy", "type": "DRUG" }, { "name": "Genetic feedback, verbal", "type": "BEHAVIORAL" }, { "name": "Genetic feedback, printed", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 36, "start_date": "2009-07", "completion_date": "2011-03", "has_results": true, "last_update_posted_date": "2012-09-19", "last_synced_at": "2026-10-12T14:03:36.547Z", "location_count": 3, "location_summary": "Menlo Park, California • Stanford, California • Seattle, Washington", "locations": [ { "city": "Menlo Park", "state": "California" }, { "city": "Stanford", "state": "California" }, { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00991081" }, { "nct_id": "NCT01965405", "title": "Smoking Cessation for People Living With HIV/AIDS", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "HIV", "AIDS", "Nicotine Dependence" ], "interventions": [ { "name": "Bupropion", "type": "DRUG" }, { "name": "Brief Counseling", "type": "BEHAVIORAL" }, { "name": "High-magnitude prize contingency management", "type": "BEHAVIORAL" }, { "name": "Monitored support to quit smoking", "type": "BEHAVIORAL" }, { "name": "No additional treatment", "type": "BEHAVIORAL" }, { "name": "Prize contingency management for abstinence", "type": "BEHAVIORAL" }, { "name": "Low intensity prize contingency management", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Wayne State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 165, "start_date": "2013-08", "completion_date": "2021-12", "has_results": false, "last_update_posted_date": "2021-07-02", "last_synced_at": "2026-10-12T14:03:36.547Z", "location_count": 1, "location_summary": "Detroit, Michigan", "locations": [ { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01965405" } ] }