{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=CEA%2C+CAS",
    "query": {
      "intervention": "CEA, CAS"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-12T13:03:08.774Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00883402",
      "title": "Carotid Endarterectomy Versus Carotid Artery Stenting in Asymptomatic Patients",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Carotid Stenosis"
      ],
      "interventions": [
        {
          "name": "CEA, CAS",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Oxford",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3638,
      "start_date": "2008-01",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2024-12-09",
      "last_synced_at": "2026-09-12T13:03:08.774Z",
      "location_count": 1,
      "location_summary": "Toledo, Ohio",
      "locations": [
        {
          "city": "Toledo",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00883402"
    },
    {
      "nct_id": "NCT02089217",
      "title": "Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Carotid Stenosis"
      ],
      "interventions": [
        {
          "name": "Carotid endarterectomy (CEA)",
          "type": "PROCEDURE"
        },
        {
          "name": "Carotid Stenting (CAS)",
          "type": "DEVICE"
        },
        {
          "name": "Intensive Medical Management - no CEA",
          "type": "OTHER"
        },
        {
          "name": "Intensive Medical Management - no CAS",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "35 Years to 100 Years"
      },
      "enrollment_count": 2486,
      "start_date": "2014-12-09",
      "completion_date": "2025-09-12",
      "has_results": false,
      "last_update_posted_date": "2025-10-01",
      "last_synced_at": "2026-09-12T13:03:08.774Z",
      "location_count": 154,
      "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 112 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02089217"
    },
    {
      "nct_id": "NCT00004732",
      "title": "Carotid Revascularization Endarterectomy Versus Stenting Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atherosclerosis",
        "Stroke",
        "Carotid Stenosis",
        "Cerebral Infarction",
        "Myocardial Infarction"
      ],
      "interventions": [
        {
          "name": "Carotid Endarterectomy (CEA)",
          "type": "PROCEDURE"
        },
        {
          "name": "Carotid Artery Stenting (CAS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2502,
      "start_date": "2000-12",
      "completion_date": "2016-12",
      "has_results": true,
      "last_update_posted_date": "2017-05-17",
      "last_synced_at": "2026-09-12T13:03:08.774Z",
      "location_count": 106,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 84 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00004732"
    },
    {
      "nct_id": "NCT03121209",
      "title": "Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Internal Carotid Artery Stenosis",
        "Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Revascularization",
          "type": "PROCEDURE"
        },
        {
          "name": "Intensive Medical Management (IMM) alone",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "86 Years",
        "sex": "ALL",
        "summary": "35 Years to 86 Years"
      },
      "enrollment_count": 392,
      "start_date": "2018-01-18",
      "completion_date": "2025-09-12",
      "has_results": false,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-09-12T13:03:08.774Z",
      "location_count": 56,
      "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 45 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03121209"
    },
    {
      "nct_id": "NCT02118233",
      "title": "Cognitive Outcome After Carotid Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Carotid Stenosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Lahey Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 56,
      "start_date": "2014-04",
      "completion_date": "2019-11",
      "has_results": false,
      "last_update_posted_date": "2019-11-26",
      "last_synced_at": "2026-09-12T13:03:08.774Z",
      "location_count": 3,
      "location_summary": "Burlington, Massachusetts • Buffalo, New York • Stony Brook, New York",
      "locations": [
        {
          "city": "Burlington",
          "state": "Massachusetts"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02118233"
    },
    {
      "nct_id": "NCT00271076",
      "title": "CAPITAL: Carotid Artery Plaque Intravascular Ultrasound Evaluation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Carotid Artery Disease"
      ],
      "interventions": [
        {
          "name": "IVUS",
          "type": "PROCEDURE"
        },
        {
          "name": "CAS",
          "type": "DEVICE"
        },
        {
          "name": "CEA",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Arizona Heart Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2006-01",
      "completion_date": "2007-09",
      "has_results": false,
      "last_update_posted_date": "2007-10-25",
      "last_synced_at": "2026-09-12T13:03:08.774Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00271076"
    },
    {
      "nct_id": "NCT00106938",
      "title": "Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard Risk for Carotid Endarterectomy With Significant Extracranial Carotid Stenotic Disease (ACT I)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Carotid Artery Disease",
        "Carotid Stenosis",
        "Stroke",
        "Atherosclerosis"
      ],
      "interventions": [
        {
          "name": "Carotid artery stenting with filter (interventional)",
          "type": "DEVICE"
        },
        {
          "name": "Carotid artery endarterectomy (surgical)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 1663,
      "start_date": "2005-04",
      "completion_date": "2013-03",
      "has_results": true,
      "last_update_posted_date": "2017-07-19",
      "last_synced_at": "2026-09-12T13:03:08.774Z",
      "location_count": 62,
      "location_summary": "Phoenix, Arizona • Mountain View, California • Newport Beach, California + 52 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Mountain View",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00106938"
    },
    {
      "nct_id": "NCT05465122",
      "title": "CREST-2 Long-term Observational Extension Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stenoses, Carotid"
      ],
      "interventions": [
        {
          "name": "Carotid Endarterectomy",
          "type": "PROCEDURE"
        },
        {
          "name": "FDA-approved carotid stents",
          "type": "PROCEDURE"
        },
        {
          "name": "Intensive Medical Management",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "35 Years and older"
      },
      "enrollment_count": 2480,
      "start_date": "2022-07-05",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-28",
      "last_synced_at": "2026-09-12T13:03:08.774Z",
      "location_count": 61,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 51 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Fremont",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05465122"
    }
  ]
}