{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=CLEAR+CARE%C2%AE&page=2",
    "query": {
      "intervention": "CLEAR CARE®",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 33,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=CLEAR+CARE%C2%AE&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=CLEAR+CARE%C2%AE&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-30T06:36:53.497Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04300140",
      "title": "Safety and Efficacy Study of AVB-S6-500 (Batiraxcept) in Patients With Advanced or Metastatic Clear Cell Renal Cell Carcinoma",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Clear Cell Renal Cell Carcinoma"
      ],
      "interventions": [
        {
          "name": "Batiraxcept",
          "type": "DRUG"
        },
        {
          "name": "Cabozantinib (Cabo)",
          "type": "DRUG"
        },
        {
          "name": "Nivolumab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Aravive, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 72,
      "start_date": "2021-02-26",
      "completion_date": "2023-08-14",
      "has_results": false,
      "last_update_posted_date": "2023-10-30",
      "last_synced_at": "2026-09-30T06:36:53.497Z",
      "location_count": 17,
      "location_summary": "Baltimore, Maryland • Boston, Massachusetts • Detroit, Michigan + 13 more",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04300140"
    },
    {
      "nct_id": "NCT05211739",
      "title": "Clinical Assessment of a Daily Wear Monthly Replacement Silicone Hydrogel Toric Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A toric contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A toric contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "CLEAR CARE",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 76,
      "start_date": "2022-02-15",
      "completion_date": "2022-06-23",
      "has_results": true,
      "last_update_posted_date": "2023-06-27",
      "last_synced_at": "2026-09-30T06:36:53.497Z",
      "location_count": 7,
      "location_summary": "Longwood, Florida • Maitland, Florida • Orlando, Florida + 4 more",
      "locations": [
        {
          "city": "Longwood",
          "state": "Florida"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Pittsburg",
          "state": "Kansas"
        },
        {
          "city": "Willmar",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05211739"
    },
    {
      "nct_id": "NCT04532099",
      "title": "Clinical Comparison of Two Daily Wear Frequent Replacement Silicone Hydrogel Soft Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors",
        "Ametropia"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Senofilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Hydrogen peroxide-based cleaning and disinfecting solution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 132,
      "start_date": "2020-09-09",
      "completion_date": "2021-05-04",
      "has_results": true,
      "last_update_posted_date": "2022-05-03",
      "last_synced_at": "2026-09-30T06:36:53.497Z",
      "location_count": 4,
      "location_summary": "Longwood, Florida • Maitland, Florida • Warwick, Rhode Island + 1 more",
      "locations": [
        {
          "city": "Longwood",
          "state": "Florida"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Warwick",
          "state": "Rhode Island"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04532099"
    },
    {
      "nct_id": "NCT01250925",
      "title": "Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Myopia",
        "Refractive Error"
      ],
      "interventions": [
        {
          "name": "ReNu MultiPlus® MultiPurpose Solution",
          "type": "DRUG"
        },
        {
          "name": "OPTI-FREE® RepleniSH®",
          "type": "DRUG"
        },
        {
          "name": "Clear Care®",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts Eye and Ear Infirmary",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 94,
      "start_date": "2010-08",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2017-01-10",
      "last_synced_at": "2026-09-30T06:36:53.497Z",
      "location_count": 2,
      "location_summary": "Iowa City, Iowa • Boston, Massachusetts",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01250925"
    },
    {
      "nct_id": "NCT05765227",
      "title": "Clinical Evaluation of a Manufacturing Process for a Frequent Replacement Silicone Hydrogel Multifocal Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Ametropia"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Hydrogen peroxide-based cleaning and disinfection system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2023-03-08",
      "completion_date": "2023-03-30",
      "has_results": true,
      "last_update_posted_date": "2024-04-16",
      "last_synced_at": "2026-09-30T06:36:53.497Z",
      "location_count": 1,
      "location_summary": "Johns Creek, Georgia",
      "locations": [
        {
          "city": "Johns Creek",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05765227"
    },
    {
      "nct_id": "NCT04314895",
      "title": "Trial of NanoPac Intratumoral Injection in Lung Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lung Cancer, Nonsmall Cell",
        "Lung Cancer",
        "Lung Cancer, Small Cell",
        "Neoplasm of Lung"
      ],
      "interventions": [
        {
          "name": "NanoPac (sterile nanoparticulate paclitaxel) Powder for Suspension",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NanOlogy, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2021-04-14",
      "completion_date": "2023-09-26",
      "has_results": true,
      "last_update_posted_date": "2025-05-23",
      "last_synced_at": "2026-09-30T06:36:53.497Z",
      "location_count": 4,
      "location_summary": "Gainesville, Florida • Fort Wayne, Indiana • Baltimore, Maryland + 1 more",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04314895"
    },
    {
      "nct_id": "NCT00799422",
      "title": "Evaluation of Contact Lenses and Conjunctival Staining in Normal Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Conjunctival Staining"
      ],
      "interventions": [
        {
          "name": "Complete Easy Rub",
          "type": "DEVICE"
        },
        {
          "name": "ReNu MultiPlus",
          "type": "DEVICE"
        },
        {
          "name": "Clear Care",
          "type": "DEVICE"
        },
        {
          "name": "Contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2008-11",
      "completion_date": "2009-03",
      "has_results": true,
      "last_update_posted_date": "2012-11-16",
      "last_synced_at": "2026-09-30T06:36:53.497Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00799422"
    },
    {
      "nct_id": "NCT05649904",
      "title": "AFFECT Study for Patients With Intraventricular Hemorrhage, Subarachnoid Hemorrhage, Subdural Hematoma, and Ventriculitis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intraventricular Hemorrhage",
        "Subarachnoid Hemorrhage",
        "Subdural Hematoma",
        "Ventriculitis"
      ],
      "interventions": [
        {
          "name": "IRRAflow with Active Fluid Exchange System",
          "type": "DEVICE"
        },
        {
          "name": "External Ventricular Drain",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 240,
      "start_date": "2023-02-07",
      "completion_date": "2026-01",
      "has_results": false,
      "last_update_posted_date": "2025-04-01",
      "last_synced_at": "2026-09-30T06:36:53.497Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05649904"
    },
    {
      "nct_id": "NCT06165627",
      "title": "Comparison of Clinical Performance of Two Monthly Replacement Toric Soft Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ametropia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A toric contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A toric contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "CLEAR CARE",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 67,
      "start_date": "2024-01-23",
      "completion_date": "2024-05-12",
      "has_results": true,
      "last_update_posted_date": "2025-05-29",
      "last_synced_at": "2026-09-30T06:36:53.497Z",
      "location_count": 5,
      "location_summary": "Los Angeles, California • Oakland, California • San Francisco, California + 2 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Granville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06165627"
    },
    {
      "nct_id": "NCT03026257",
      "title": "Clinical Assessment of a HYDRAGLYDE® Regimen",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors",
        "Myopia",
        "Hypermetropia"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B contact lenses with added wetting agent",
          "type": "DEVICE"
        },
        {
          "name": "Samfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "POLYQUAD/ALDOX-preserved contact lens solution with added wetting agent",
          "type": "DEVICE"
        },
        {
          "name": "Hydrogen peroxide-based contact lens solution with added wetting agent",
          "type": "DEVICE"
        },
        {
          "name": "Senofilcon C contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Senofilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Habitual Multi-Purpose Solution (HMPS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon, a Novartis Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 323,
      "start_date": "2017-02-13",
      "completion_date": "2017-08-18",
      "has_results": true,
      "last_update_posted_date": "2018-08-14",
      "last_synced_at": "2026-09-30T06:36:53.497Z",
      "location_count": 5,
      "location_summary": "Birmingham, Alabama • Cleveland, Ohio • Columbus, Ohio + 2 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03026257"
    }
  ]
}