{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=CNS+Vital+Signs",
    "query": {
      "intervention": "CNS Vital Signs"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-12T05:47:32.952Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02962050",
      "title": "Delineating Swallowing Impairment and Decline in ALS",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amyotrophic Lateral Sclerosis"
      ],
      "interventions": [
        {
          "name": "Videofluoroscopic Swallowing Study (VFSS)",
          "type": "PROCEDURE"
        },
        {
          "name": "Voluntary Peak Cough Flow Testing",
          "type": "DEVICE"
        },
        {
          "name": "Iowa Oral Performance Instrument",
          "type": "DEVICE"
        },
        {
          "name": "Capsaicin Challenge",
          "type": "DRUG"
        },
        {
          "name": "Pulmonary Function Testing",
          "type": "DEVICE"
        },
        {
          "name": "Eating Assessment Tool 10",
          "type": "OTHER"
        },
        {
          "name": "The Center for Neurologic Study Bulbar Function Scale",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 109,
      "start_date": "2017-05-31",
      "completion_date": "2023-02-16",
      "has_results": false,
      "last_update_posted_date": "2023-02-23",
      "last_synced_at": "2026-09-12T05:47:32.952Z",
      "location_count": 2,
      "location_summary": "Gainesville, Florida • Tampa, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02962050"
    },
    {
      "nct_id": "NCT02710162",
      "title": "Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Amyotrophic Lateral Sclerosis"
      ],
      "interventions": [
        {
          "name": "Micro Mouth Pressure Meter",
          "type": "DEVICE"
        },
        {
          "name": "Iowa Oral Performance Instrument",
          "type": "DEVICE"
        },
        {
          "name": "Electrical Impedance Myography",
          "type": "DEVICE"
        },
        {
          "name": "Capsaicin",
          "type": "DRUG"
        },
        {
          "name": "Videofluoroscopic Swallowing Study",
          "type": "PROCEDURE"
        },
        {
          "name": "Pulmonary Function Testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Swallowing Related Quality of Life Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Functional Oral Intake Scale",
          "type": "OTHER"
        },
        {
          "name": "Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised",
          "type": "OTHER"
        },
        {
          "name": "Eating Assessment Tool-10",
          "type": "OTHER"
        },
        {
          "name": "Communicative Effectiveness Survey",
          "type": "OTHER"
        },
        {
          "name": "The Center for Neurologic Studies Bulbar Function Scale",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG",
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 21,
      "start_date": "2016-04",
      "completion_date": "2017-12-19",
      "has_results": false,
      "last_update_posted_date": "2017-12-21",
      "last_synced_at": "2026-09-12T05:47:32.952Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02710162"
    },
    {
      "nct_id": "NCT06521502",
      "title": "The APS Phenotyping Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ARDS",
        "Sepsis",
        "Pneumonia"
      ],
      "interventions": [
        {
          "name": "Blood collection",
          "type": "OTHER"
        },
        {
          "name": "Urine Collection",
          "type": "OTHER"
        },
        {
          "name": "Nasal, oral, and rectal swabs",
          "type": "OTHER"
        },
        {
          "name": "Stool collection",
          "type": "OTHER"
        },
        {
          "name": "Heat Moisture Exchange Filter collection",
          "type": "OTHER"
        },
        {
          "name": "Tracheal Aspirate sample collection",
          "type": "OTHER"
        },
        {
          "name": "Non-bronchoscopic bronchoalveolar lavage (NBBAL)",
          "type": "PROCEDURE"
        },
        {
          "name": "Surveys",
          "type": "OTHER"
        },
        {
          "name": "Short physical performance battery",
          "type": "OTHER"
        },
        {
          "name": "Hand grip strength",
          "type": "OTHER"
        },
        {
          "name": "CNS Vital Signs",
          "type": "OTHER"
        },
        {
          "name": "Muscle Ultrasound",
          "type": "OTHER"
        },
        {
          "name": "Muscle Strength",
          "type": "OTHER"
        },
        {
          "name": "Spirometry",
          "type": "OTHER"
        },
        {
          "name": "Lung Diffusion Testing (DLCO)",
          "type": "OTHER"
        },
        {
          "name": "Chest CT Scan",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE",
        "RADIATION"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4000,
      "start_date": "2024-07-25",
      "completion_date": "2029-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-09-12T05:47:32.952Z",
      "location_count": 20,
      "location_summary": "Fresno, California • Palo Alto, California • San Francisco, California + 12 more",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06521502"
    },
    {
      "nct_id": "NCT05540535",
      "title": "Dual-Task Cost in Bilateral Hearing Loss",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bilateral Hearing Loss",
        "Healthy Aging"
      ],
      "interventions": [
        {
          "name": "Gait assessment",
          "type": "OTHER"
        },
        {
          "name": "Cognitive assessment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "New York University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 67,
      "start_date": "2022-02-01",
      "completion_date": "2024-11-22",
      "has_results": true,
      "last_update_posted_date": "2025-01-13",
      "last_synced_at": "2026-09-12T05:47:32.952Z",
      "location_count": 2,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05540535"
    },
    {
      "nct_id": "NCT05480904",
      "title": "Characterizing Sleep Among Long-term Survivors of Childhood Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ALL, Adult",
        "CNS Tumor",
        "Solid Tumor"
      ],
      "interventions": [
        {
          "name": "Neurocognitive (Thinking) Testing",
          "type": "OTHER"
        },
        {
          "name": "CNS Vital Signs (Thinking) Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Health Questionnaires, Sleep Surveys & Sleep Diary",
          "type": "OTHER"
        },
        {
          "name": "Echocardiography/EKG",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Pulmonary Function",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Remote Polysomnography",
          "type": "DEVICE"
        },
        {
          "name": "Physical Function",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST",
        "DEVICE"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 199,
      "start_date": "2023-04-17",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-19",
      "last_synced_at": "2026-09-12T05:47:32.952Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05480904"
    },
    {
      "nct_id": "NCT05063565",
      "title": "TheraSphere With Durvalumab and Tremelimumab for HCC",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hepatocellular Carcinoma"
      ],
      "interventions": [
        {
          "name": "TheraSphere Y-90 glass microsphere therapy",
          "type": "DEVICE"
        },
        {
          "name": "Durvalumab (Imfinzi) immunotherapy",
          "type": "DRUG"
        },
        {
          "name": "Tremelimumab immunotherapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2023-11-03",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-08-26",
      "last_synced_at": "2026-09-12T05:47:32.952Z",
      "location_count": 12,
      "location_summary": "San Diego, California • San Francisco, California • Washington D.C., District of Columbia + 7 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05063565"
    },
    {
      "nct_id": "NCT07191119",
      "title": "Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Survivor of Childhood Cancer",
        "Insomnia",
        "Acute Lymphoblastic Leukemia (ALL)"
      ],
      "interventions": [
        {
          "name": "Soterix tVNS device",
          "type": "DEVICE"
        },
        {
          "name": "Soterix tVNS device (sham programmed)",
          "type": "DEVICE"
        },
        {
          "name": "Sleep Quality",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Neurocognitive and mental health outcomes",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "20 Years to 50 Years"
      },
      "enrollment_count": 40,
      "start_date": "2026-03-31",
      "completion_date": "2029-12",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-09-12T05:47:32.952Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07191119"
    },
    {
      "nct_id": "NCT02445651",
      "title": "Physiological Effects of Nutritional Support in Patients With Parkinson's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease",
        "Idiopathic Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "Intravenous and Oral n-acetyl cysteine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Control group",
          "type": "OTHER"
        },
        {
          "name": "Oral Supplements: Baicalin, Ganoderma, Omega 3 and Curcumin",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "30 Years to 80 Years"
      },
      "enrollment_count": 51,
      "start_date": "2014-03",
      "completion_date": "2022-08-04",
      "has_results": true,
      "last_update_posted_date": "2025-12-15",
      "last_synced_at": "2026-09-12T05:47:32.952Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02445651"
    }
  ]
}