{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=COX+Inhibitor", "query": { "intervention": "COX Inhibitor" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 25, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=COX+Inhibitor&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-12T19:51:19.974Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00663767", "title": "A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dental Pain" ], "interventions": [ { "name": "Placebo; oral", "type": "DRUG" }, { "name": "ARRY-371797, p38 inhibitor; oral", "type": "DRUG" }, { "name": "Celecoxib, COX-2 inhibitor; oral", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 250, "start_date": "2008-04-07", "completion_date": "2008-06-20", "has_results": false, "last_update_posted_date": "2021-02-09", "last_synced_at": "2026-09-12T19:51:19.974Z", "location_count": 2, "location_summary": "Austin, Texas • Salt Lake City, Utah", "locations": [ { "city": "Austin", "state": "Texas" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT00663767" }, { "nct_id": "NCT03710876", "title": "Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Malignant Pleural Mesothelioma" ], "interventions": [ { "name": "rAd-IFN", "type": "BIOLOGICAL" }, { "name": "Celecoxib Oral Product", "type": "DRUG" }, { "name": "Gemcitabine", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Ferring Ventures Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 53, "start_date": "2019-01-21", "completion_date": "2026-01-16", "has_results": true, "last_update_posted_date": "2026-04-21", "last_synced_at": "2026-09-12T19:51:19.974Z", "location_count": 7, "location_summary": "Los Angeles, California • San Francisco, California • Tampa, Florida + 3 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Tampa", "state": "Florida" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03710876" }, { "nct_id": "NCT02073435", "title": "A2ALL-Patients Safety System Improvements in Living Donor Liver Transplantation", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Liver Diseases", "Hepatocellular Cancer", "Endstage Liver Disease", "Liver Cirrhosis" ], "interventions": [ { "name": "Donor pain management", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "21 Years to 60 Years" }, "enrollment_count": 177, "start_date": "2010-10", "completion_date": "2018-04", "has_results": true, "last_update_posted_date": "2018-12-05", "last_synced_at": "2026-09-12T19:51:19.974Z", "location_count": 4, "location_summary": "Chicago, Illinois • Burlington, Massachusetts • New York, New York + 1 more", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "Burlington", "state": "Massachusetts" }, { "city": "New York", "state": "New York" }, { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02073435" }, { "nct_id": "NCT02578706", "title": "Targeting Platelets in Chronic HIV Infection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "HIV-1 Infection" ], "interventions": [ { "name": "Clopidogrel", "type": "DRUG" }, { "name": "Aspirin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Icahn School of Medicine at Mount Sinai", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 27, "start_date": "2015-10", "completion_date": "2016-11", "has_results": true, "last_update_posted_date": "2018-02-28", "last_synced_at": "2026-09-12T19:51:19.974Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02578706" }, { "nct_id": "NCT00299195", "title": "A Randomized Study of Sulindac in Oral Premalignant Lesions", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Leukoplakia, Oral", "Benign Neoplasms" ], "interventions": [ { "name": "sulindac", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 63, "start_date": "2006-02-23", "completion_date": "2020-01-06", "has_results": true, "last_update_posted_date": "2020-11-19", "last_synced_at": "2026-09-12T19:51:19.974Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00299195" }, { "nct_id": "NCT00046839", "title": "Celecoxib and Radiation Therapy in Treating Patients With Locally Advanced Non-Small Cell Lung Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Lung Cancer" ], "interventions": [ { "name": "celecoxib", "type": "DRUG" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "Radiation Therapy Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 21, "start_date": "2002-07", "completion_date": null, "has_results": true, "last_update_posted_date": "2015-11-17", "last_synced_at": "2026-09-12T19:51:19.974Z", "location_count": 44, "location_summary": "Colorado Springs, Colorado • Gainesville, Florida • Jacksonville, Florida + 37 more", "locations": [ { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Rome", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00046839" }, { "nct_id": "NCT02205983", "title": "The Effects of Hydromorphone on Responses to Verbal Tasks", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "2 mg hydromorphone", "type": "DRUG" }, { "name": "1000 mg Acetaminophen", "type": "DRUG" }, { "name": "4 mg hydromorphone", "type": "DRUG" }, { "name": "dextrose", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 50, "start_date": "2015-01", "completion_date": "2016-09", "has_results": true, "last_update_posted_date": "2018-10-09", "last_synced_at": "2026-09-12T19:51:19.974Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02205983" }, { "nct_id": "NCT06533904", "title": "Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Trauma", "Rib Fractures", "Chest Wall Disorder", "Respiratory Insufficiency", "Pain, Chest", "Rib Trauma", "Rib Fracture Multiple", "Respiratory Failure", "Respiratory Distress Syndrome" ], "interventions": [ { "name": "Percutaneous Cryoablation of Intercostal Nerves", "type": "PROCEDURE" }, { "name": "Multi-modal pain regimen", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "OTHER" ], "sponsor": "Loma Linda University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 30, "start_date": "2026-09", "completion_date": "2028-07", "has_results": false, "last_update_posted_date": "2026-02-09", "last_synced_at": "2026-09-12T19:51:19.974Z", "location_count": 1, "location_summary": "Loma Linda, California", "locations": [ { "city": "Loma Linda", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06533904" }, { "nct_id": "NCT00001693", "title": "Phase I-II Multiple-Dose Safety and Efficacy Study of a Selective Inhibitor of Cyclooxygenase - 2 (SC-58635) in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients and Carriers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Colorectal Neoplasm", "Hereditary Nonpolyposis" ], "interventions": [ { "name": "Celecoxib (SC-58635)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 20, "start_date": "1998-03", "completion_date": "2002-01", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-09-12T19:51:19.974Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001693" }, { "nct_id": "NCT02509312", "title": "Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Analgesia, Obstetrical", "Postpartum Hemorrhage", "Opioid Use", "Nonsteroidals (NSAIDs)Toxicity", "Coagulation Defect; Postpartum", "Postoperative Pain", "Ketorolac Adverse Reaction", "Blood Loss, Postoperative" ], "interventions": [ { "name": "Ketorolac", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University Hospitals Cleveland Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "FEMALE", "summary": "18 Years to 45 Years · Female only" }, "enrollment_count": 70, "start_date": "2016-05", "completion_date": "2017-10", "has_results": true, "last_update_posted_date": "2022-06-07", "last_synced_at": "2026-09-12T19:51:19.974Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02509312" } ] }