{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=CT+Manipulation",
    "query": {
      "intervention": "CT Manipulation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-13T13:22:04.750Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03215719",
      "title": "Adaptive Treatment De-escalation in Favorable Risk HPV-Positive Oropharyngeal Carcinoma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Oropharyngeal Carcinoma",
        "HPV Positive Oropharyngeal Squamous Cell Carcinoma"
      ],
      "interventions": [
        {
          "name": "Standard Radiation Treatment",
          "type": "RADIATION"
        },
        {
          "name": "Dose-Deescalated Treatment",
          "type": "RADIATION"
        },
        {
          "name": "Cisplatinum",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "RADIATION",
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2017-10-18",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-06",
      "last_synced_at": "2026-09-13T13:22:04.750Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03215719"
    },
    {
      "nct_id": "NCT00499083",
      "title": "Paclitaxel, Cyclophosphamide & Doxorubicin, Autologous Dendritic Cells & Surgery in Stage II/III Breast Cancer (Women)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "therapeutic autologous dendritic cells",
          "type": "BIOLOGICAL"
        },
        {
          "name": "aromatase inhibition therapy",
          "type": "DRUG"
        },
        {
          "name": "cyclophosphamide",
          "type": "DRUG"
        },
        {
          "name": "doxorubicin hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "paclitaxel",
          "type": "DRUG"
        },
        {
          "name": "tamoxifen citrate",
          "type": "DRUG"
        },
        {
          "name": "gene expression analysis",
          "type": "GENETIC"
        },
        {
          "name": "protein expression analysis",
          "type": "GENETIC"
        },
        {
          "name": "reverse transcriptase-polymerase chain reaction",
          "type": "GENETIC"
        },
        {
          "name": "immunoenzyme technique",
          "type": "OTHER"
        },
        {
          "name": "immunohistochemistry staining method",
          "type": "OTHER"
        },
        {
          "name": "laboratory biomarker analysis",
          "type": "OTHER"
        },
        {
          "name": "adjuvant therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "conventional surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "neoadjuvant therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "radiation therapy",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG",
        "GENETIC",
        "OTHER",
        "PROCEDURE",
        "RADIATION"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "120 Years",
        "sex": "FEMALE",
        "summary": "19 Years to 120 Years · Female only"
      },
      "enrollment_count": 17,
      "start_date": "2006-05-01",
      "completion_date": "2010-01-28",
      "has_results": true,
      "last_update_posted_date": "2023-09-29",
      "last_synced_at": "2026-09-13T13:22:04.750Z",
      "location_count": 2,
      "location_summary": "Tampa, Florida • Omaha, Nebraska",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00499083"
    },
    {
      "nct_id": "NCT02081430",
      "title": "Immediate Effects of Manipulation Versus Stretching on Upper Trapezius Pressure Pain Thresholds",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurophysiological Mechanisms Manipulation"
      ],
      "interventions": [
        {
          "name": "CT Manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Upper trapezius stretch",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Nevada, Las Vegas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 90,
      "start_date": "2013-05",
      "completion_date": "2014-08",
      "has_results": false,
      "last_update_posted_date": "2014-11-05",
      "last_synced_at": "2026-09-13T13:22:04.750Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02081430"
    },
    {
      "nct_id": "NCT03886168",
      "title": "Pediatric Image-Guided Cochlear Implant Programming",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cochlear Implant"
      ],
      "interventions": [
        {
          "name": "Signal processing intervention of a biomedical device",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "13 Years",
        "sex": "ALL",
        "summary": "4 Years to 13 Years"
      },
      "enrollment_count": 47,
      "start_date": "2019-06-30",
      "completion_date": "2025-06-30",
      "has_results": true,
      "last_update_posted_date": "2026-08-24",
      "last_synced_at": "2026-09-13T13:22:04.750Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03886168"
    },
    {
      "nct_id": "NCT04555239",
      "title": "FDM for Subacute and Chronic Extremity Pain in the ED",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myofascial Pain",
        "Chronic Pain",
        "Extremities Disorders",
        "Osteopathic Manipulation"
      ],
      "interventions": [
        {
          "name": "Fascial Distortion Model (FDM)",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Carilion Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2020-12-01",
      "completion_date": "2022-02-25",
      "has_results": false,
      "last_update_posted_date": "2022-04-04",
      "last_synced_at": "2026-09-13T13:22:04.750Z",
      "location_count": 4,
      "location_summary": "Christiansburg, Virginia • Lexington, Virginia • Roanoke, Virginia + 1 more",
      "locations": [
        {
          "city": "Christiansburg",
          "state": "Virginia"
        },
        {
          "city": "Lexington",
          "state": "Virginia"
        },
        {
          "city": "Roanoke",
          "state": "Virginia"
        },
        {
          "city": "Rocky Mount",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04555239"
    },
    {
      "nct_id": "NCT02708953",
      "title": "Thoracic Spine Thrust Manipulation for Cervicogenic Headaches: A Randomized Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Headache Disorders, Secondary"
      ],
      "interventions": [
        {
          "name": "Thoracic manipulation (Manipulation Group)",
          "type": "PROCEDURE"
        },
        {
          "name": "Thoracic Manipulation (Control wait-list)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 48,
      "start_date": "2016-05",
      "completion_date": "2019-09-19",
      "has_results": false,
      "last_update_posted_date": "2021-02-04",
      "last_synced_at": "2026-09-13T13:22:04.750Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02708953"
    }
  ]
}