{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Caffeine",
    "query": {
      "intervention": "Caffeine"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 471,
    "total_pages": 48,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Caffeine&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T00:24:50.243Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04813276",
      "title": "Efficacy of a Self-advocacy Serious Game Intervention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Self-Management",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Strong Together serious game",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Care as Usual",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 344,
      "start_date": "2022-08-22",
      "completion_date": "2026-06-11",
      "has_results": false,
      "last_update_posted_date": "2026-07-16",
      "last_synced_at": "2026-09-02T00:24:50.243Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04813276"
    },
    {
      "nct_id": "NCT02411318",
      "title": "Influence of Lifestyle Factors on Neutrophil Migration Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neutrophil Chemotactic Response"
      ],
      "interventions": [
        {
          "name": "Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "ProLab 200mg caffeine capsule",
          "type": "DRUG"
        },
        {
          "name": "Ethanol ingestion",
          "type": "OTHER"
        },
        {
          "name": "Glucose Tolerance Drink",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 47,
      "start_date": "2014-09-25",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-12-17",
      "last_synced_at": "2026-09-02T00:24:50.243Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02411318"
    },
    {
      "nct_id": "NCT01988974",
      "title": "Feasibility Testing of the Alert for Atrial Fibrillation Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Alert for Atrial Fibrillation Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Healthy Sleep",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2013-11",
      "completion_date": "2015-09",
      "has_results": false,
      "last_update_posted_date": "2017-03-24",
      "last_synced_at": "2026-09-02T00:24:50.243Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01988974"
    },
    {
      "nct_id": "NCT04056650",
      "title": "Assessing the Effectiveness of an N-of-1 Platform Using Study of Cognitive Enhancers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cognitive Performance"
      ],
      "interventions": [
        {
          "name": "L-theanine",
          "type": "DRUG"
        },
        {
          "name": "Caffeine supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "N1 app",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT",
        "DEVICE"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 57,
      "start_date": "2019-10-18",
      "completion_date": "2020-12-22",
      "has_results": false,
      "last_update_posted_date": "2021-03-12",
      "last_synced_at": "2026-09-02T00:24:50.243Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04056650"
    },
    {
      "nct_id": "NCT04923685",
      "title": "MicroRNA Correlates of Childhood Maltreatment and Suicidality",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Depressive Disorder",
        "Suicidal Ideation"
      ],
      "interventions": [
        {
          "name": "Trier Social Stress Test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 450,
      "start_date": "2021-02-26",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-30",
      "last_synced_at": "2026-09-02T00:24:50.243Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Huntsville, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Huntsville",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04923685"
    },
    {
      "nct_id": "NCT00207285",
      "title": "Sleep Disorders Management, Health and Safety in Police",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Disorders",
        "Sleep Apnea, Obstructive",
        "Restless Legs Syndrome",
        "Sleep Disorders, Circadian Rhythm",
        "Sleep Initiation and Maintenance Disorders"
      ],
      "interventions": [
        {
          "name": "Sleep Hygiene Education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Screening and Treatment of Sleep Disorders",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 731,
      "start_date": "2005-05",
      "completion_date": "2010-09",
      "has_results": false,
      "last_update_posted_date": "2016-03-17",
      "last_synced_at": "2026-09-02T00:24:50.243Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00207285"
    },
    {
      "nct_id": "NCT05412927",
      "title": "AngelMed Guardian® System PMA Post Approval Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Coronary Syndrome"
      ],
      "interventions": [
        {
          "name": "PMA P150009 AngelMed Guardian® System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Angel Medical Systems",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2022-09-07",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-09-30",
      "last_synced_at": "2026-09-02T00:24:50.243Z",
      "location_count": 18,
      "location_summary": "Glendale, Arizona • Mesa, Arizona • Los Angeles, California + 14 more",
      "locations": [
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05412927"
    },
    {
      "nct_id": "NCT02786953",
      "title": "Sleep Promotion to Improve Diabetes Management in Adolescents With T1D",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 1"
      ],
      "interventions": [
        {
          "name": "Sleep Promotion",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "13 Years to 17 Years"
      },
      "enrollment_count": 40,
      "start_date": "2017-10-19",
      "completion_date": "2019-02-05",
      "has_results": true,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-09-02T00:24:50.243Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02786953"
    },
    {
      "nct_id": "NCT03583957",
      "title": "A Wireless EEG Patch for Continuous Electrographic Monitoring",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epilepsy"
      ],
      "interventions": [
        {
          "name": "Observational only",
          "type": "DEVICE"
        },
        {
          "name": "Psychological and Behavioral interaction with a seizure forecasting mobile app",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Seizure Alerting and Prediction System",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL",
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Epitel, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Years and older"
      },
      "enrollment_count": 750,
      "start_date": "2018-05-08",
      "completion_date": "2026-04-30",
      "has_results": false,
      "last_update_posted_date": "2024-02-16",
      "last_synced_at": "2026-09-02T00:24:50.243Z",
      "location_count": 3,
      "location_summary": "Aurora, Colorado • Boston, Massachusetts • New York, New York",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03583957"
    },
    {
      "nct_id": "NCT01369485",
      "title": "Safety and Effectiveness of a Non-invasive Neuromodulation Device on Urgency Urinary Incontinence in Overactive Bladder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overactive Bladder"
      ],
      "interventions": [
        {
          "name": "(VERV™ System)",
          "type": "DEVICE"
        },
        {
          "name": "Sham version of (VERV™ System)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ethicon Endo-Surgery",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 163,
      "start_date": "2011-06",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2014-09-11",
      "last_synced_at": "2026-09-02T00:24:50.243Z",
      "location_count": 14,
      "location_summary": "Tucson, Arizona • Murrieta, California • Washington D.C., District of Columbia + 11 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Murrieta",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Naples",
          "state": "Florida"
        },
        {
          "city": "Pompano Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01369485"
    }
  ]
}