{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Calorie+Restriction&page=4",
    "query": {
      "intervention": "Calorie Restriction",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 293,
    "total_pages": 30,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Calorie+Restriction&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Calorie+Restriction&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-21T14:12:51.898Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06887543",
      "title": "The Impact of Time Restricted Eating on Type 2 Diabetes",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "Meal timing",
          "type": "OTHER"
        },
        {
          "name": "Time restricted eating",
          "type": "OTHER"
        },
        {
          "name": "Usual feeding pattern.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rockefeller University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 2,
      "start_date": "2025-05-29",
      "completion_date": "2025-08-04",
      "has_results": false,
      "last_update_posted_date": "2026-01-20",
      "last_synced_at": "2026-10-21T14:12:51.898Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06887543"
    },
    {
      "nct_id": "NCT06477120",
      "title": "Time-restricted Eating Among Pregnant Females With Severe Obesity",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity, Morbid",
        "Time Restricted Eating",
        "Pregnancy Weight Gain"
      ],
      "interventions": [
        {
          "name": "Time Restricted Eating",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "44 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 44 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2024-09-09",
      "completion_date": "2026-11-29",
      "has_results": false,
      "last_update_posted_date": "2026-10-14",
      "last_synced_at": "2026-10-21T14:12:51.898Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06477120"
    },
    {
      "nct_id": "NCT06449287",
      "title": "Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ketogenic Diet",
        "Weight Loss"
      ],
      "interventions": [
        {
          "name": "Diet",
          "type": "OTHER"
        },
        {
          "name": "Blood Draw",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Ketone/Glucose Monitoring",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Body Composition",
          "type": "OTHER"
        },
        {
          "name": "Urine Analysis",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Neuropsychological Measures - ANAM",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BIOLOGICAL",
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 37,
      "start_date": "2018-07-05",
      "completion_date": "2019-08-21",
      "has_results": false,
      "last_update_posted_date": "2024-12-19",
      "last_synced_at": "2026-10-21T14:12:51.898Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06449287"
    },
    {
      "nct_id": "NCT01048736",
      "title": "Investigating Fitness Interventions in the Elderly (INFINITE)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Older Adults",
        "Sedentary"
      ],
      "interventions": [
        {
          "name": "Exercise Only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exercise + Diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "65 Years to 80 Years"
      },
      "enrollment_count": 180,
      "start_date": "2009-10",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2026-01-20",
      "last_synced_at": "2026-10-21T14:12:51.898Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01048736"
    },
    {
      "nct_id": "NCT03129048",
      "title": "Mediterranean Diet, Weight Loss, and Cognition in Obese Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognition",
        "Obese Older Adults",
        "Mediterranean Diet"
      ],
      "interventions": [
        {
          "name": "MedDiet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "55 Years to 85 Years"
      },
      "enrollment_count": 180,
      "start_date": "2016-09-01",
      "completion_date": "2021-04-01",
      "has_results": false,
      "last_update_posted_date": "2021-04-08",
      "last_synced_at": "2026-10-21T14:12:51.898Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03129048"
    },
    {
      "nct_id": "NCT01713764",
      "title": "A Pilot Study of the Effects of Diet and Behavioral Interventions on Health in Diabetics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetes Type II"
      ],
      "interventions": [
        {
          "name": "Low Carbohydrate Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "American Diabetes Association Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindfulness and Positive Affect Skills",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2012-10",
      "completion_date": "2013-11",
      "has_results": false,
      "last_update_posted_date": "2013-12-30",
      "last_synced_at": "2026-10-21T14:12:51.898Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01713764"
    },
    {
      "nct_id": "NCT03365531",
      "title": "RCT of Caloric Restriction vs. Alternate-Day Fasting in Non-Alcoholic Fatty Liver Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "NAFLD",
        "Obesity",
        "Diabetes Mellitus, Type 2"
      ],
      "interventions": [
        {
          "name": "Alternate Daily Fasting (ADF)",
          "type": "OTHER"
        },
        {
          "name": "Caloric Restriction (CR)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 7,
      "start_date": "2018-03-01",
      "completion_date": "2019-07-01",
      "has_results": false,
      "last_update_posted_date": "2019-09-23",
      "last_synced_at": "2026-10-21T14:12:51.898Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03365531"
    },
    {
      "nct_id": "NCT06325644",
      "title": "Well-Formulated Ketogenic Diet Polycystic Kidney Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Polycystic Kidney Disease"
      ],
      "interventions": [
        {
          "name": "Ketogenic Diet",
          "type": "OTHER"
        },
        {
          "name": "Ketone/Glucose Monitoring",
          "type": "BIOLOGICAL"
        },
        {
          "name": "CGM/CKM",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Blood Draw",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Body Composition",
          "type": "OTHER"
        },
        {
          "name": "Change in glomerular filtration rate (mg/mmol) via magnetic resonance imaging (MRI) .",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BIOLOGICAL"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2024-06-01",
      "completion_date": "2027-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-10-21T14:12:51.898Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06325644"
    },
    {
      "nct_id": "NCT00823381",
      "title": "Effect of Resvida, a Comparison With Calorie Restriction Regimen",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Metabolic Syndrome",
        "Diabetes",
        "Aging"
      ],
      "interventions": [
        {
          "name": "resveratrol",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "placebo",
          "type": "OTHER"
        },
        {
          "name": "Calorie Restriction",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 70 Years · Female only"
      },
      "enrollment_count": 58,
      "start_date": "2009-01",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2013-12-10",
      "last_synced_at": "2026-10-21T14:12:51.898Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00823381"
    },
    {
      "nct_id": "NCT06080932",
      "title": "Ketogenic Intervention in Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Ketosis"
      ],
      "interventions": [
        {
          "name": "Ketogenic Diet",
          "type": "OTHER"
        },
        {
          "name": "NIH Toolbox",
          "type": "OTHER"
        },
        {
          "name": "gradCPT",
          "type": "OTHER"
        },
        {
          "name": "Resting-state fMRI",
          "type": "OTHER"
        },
        {
          "name": "Task-fMRI",
          "type": "OTHER"
        },
        {
          "name": "CGM/CKM",
          "type": "OTHER"
        },
        {
          "name": "Blood Draw",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Sleep Monitoring",
          "type": "OTHER"
        },
        {
          "name": "Ketone/Glucose Monitoring",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Body Composition",
          "type": "OTHER"
        },
        {
          "name": "PHQ-9",
          "type": "BEHAVIORAL"
        },
        {
          "name": "WHO-5",
          "type": "BEHAVIORAL"
        },
        {
          "name": "SKID",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BIOLOGICAL",
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-02-20",
      "completion_date": "2024-12-21",
      "has_results": false,
      "last_update_posted_date": "2025-05-29",
      "last_synced_at": "2026-10-21T14:12:51.898Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06080932"
    }
  ]
}