{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Carbon+dioxide+breathing",
    "query": {
      "intervention": "Carbon dioxide breathing"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 141,
    "total_pages": 15,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Carbon+dioxide+breathing&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T06:09:32.990Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05035420",
      "title": "A Noninvasive Multimodal Biosensing Device for Screening and Monitoring Response to Treatment of Infectious Respiratory Diseases",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COVID-19",
        "Upper Respiratory Infection",
        "Lower Respiratory Infection"
      ],
      "interventions": [
        {
          "name": "Fitbit",
          "type": "DEVICE"
        },
        {
          "name": "Douglas Bag",
          "type": "DEVICE"
        },
        {
          "name": "Periflux 6000 EPOS",
          "type": "DEVICE"
        },
        {
          "name": "BIOPAC",
          "type": "DEVICE"
        },
        {
          "name": "Flowmet",
          "type": "DEVICE"
        },
        {
          "name": "NIRS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "78 Years",
        "sex": "ALL",
        "summary": "18 Years to 78 Years"
      },
      "enrollment_count": 40,
      "start_date": "2022-05-26",
      "completion_date": "2025-08-27",
      "has_results": false,
      "last_update_posted_date": "2025-09-05",
      "last_synced_at": "2026-09-25T06:09:32.990Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05035420"
    },
    {
      "nct_id": "NCT01381068",
      "title": "Quantitative End Tidal CO2 Monitoring in the Delivery Room (DR)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Delivery Room Resuscitation"
      ],
      "interventions": [
        {
          "name": "End tidal CO2 monitor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Neil Finer",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "15 Minutes",
        "sex": "ALL",
        "summary": "Up to 15 Minutes"
      },
      "enrollment_count": 50,
      "start_date": "2009-10",
      "completion_date": "2011-09",
      "has_results": true,
      "last_update_posted_date": "2019-12-17",
      "last_synced_at": "2026-09-25T06:09:32.990Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01381068"
    },
    {
      "nct_id": "NCT04672538",
      "title": "Fontan Physiology Ventilation Strategy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anesthesia",
        "Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "Low Vt protocol",
          "type": "PROCEDURE"
        },
        {
          "name": "High Vt protocol",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 32,
      "start_date": "2021-03-02",
      "completion_date": "2023-05-15",
      "has_results": false,
      "last_update_posted_date": "2023-05-17",
      "last_synced_at": "2026-09-25T06:09:32.990Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04672538"
    },
    {
      "nct_id": "NCT02922894",
      "title": "Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Sleep Apnea",
        "Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "Acute episodic hypoxia",
          "type": "PROCEDURE"
        },
        {
          "name": "Supplemental oxygen",
          "type": "PROCEDURE"
        },
        {
          "name": "Trazodone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Sham",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "John D. Dingell VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 100,
      "start_date": "2017-06-09",
      "completion_date": "2027-01-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-09-25T06:09:32.990Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02922894"
    },
    {
      "nct_id": "NCT04543825",
      "title": "Usefulness of Cardiopulmonary Exercise Testing for Cardiovascular Risk Estimation and Frailty Assessment in Liver Transplant Candidates",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiovascular Diseases+Liver Transplantation"
      ],
      "interventions": [
        {
          "name": "Cardiopulmonary exercise testing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Andres Duarte-Rojo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "45 Years to 75 Years"
      },
      "enrollment_count": 54,
      "start_date": "2020-09-25",
      "completion_date": "2022-05-31",
      "has_results": false,
      "last_update_posted_date": "2024-04-03",
      "last_synced_at": "2026-09-25T06:09:32.990Z",
      "location_count": 2,
      "location_summary": "Phoenix, Arizona • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04543825"
    },
    {
      "nct_id": "NCT02703220",
      "title": "Sleep Apnea in Elderly",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Sleep Apnea",
        "Elderly Adults"
      ],
      "interventions": [
        {
          "name": "Hyperoxia/oxygen",
          "type": "OTHER"
        },
        {
          "name": "Acetazolamide",
          "type": "DRUG"
        },
        {
          "name": "Finasteride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "60 Years to 89 Years"
      },
      "enrollment_count": 100,
      "start_date": "2015-07-03",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-21",
      "last_synced_at": "2026-09-25T06:09:32.990Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02703220"
    },
    {
      "nct_id": "NCT00665769",
      "title": "Physiological Disturbances Associated With Neonatal Intraventricular Hemorrhage",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intraventricular Hemorrhage",
        "Autoregulation"
      ],
      "interventions": [
        {
          "name": "Hypercapnia",
          "type": "OTHER"
        },
        {
          "name": "Normocapnia",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "7 Days",
        "sex": "ALL",
        "summary": "1 Minute to 7 Days"
      },
      "enrollment_count": 103,
      "start_date": "2008-06",
      "completion_date": "2015-11",
      "has_results": false,
      "last_update_posted_date": "2022-04-05",
      "last_synced_at": "2026-09-25T06:09:32.990Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00665769"
    },
    {
      "nct_id": "NCT05357066",
      "title": "Nitrous Oxide as Treatment for Fibromyalgia",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fibromyalgia",
        "Central Neuropathic Pain"
      ],
      "interventions": [
        {
          "name": "Nitrous oxide gas for inhalation",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 0,
      "start_date": "2021-11-12",
      "completion_date": "2026-02-27",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-09-25T06:09:32.990Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05357066"
    },
    {
      "nct_id": "NCT07420530",
      "title": "Respiratory and Real-time Dynamics in Exercise-Induced Paradoxical Vocal Fold Motion",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Exercise-Induced Vocal Cord Dysfunction",
        "Paradoxical Vocal Fold Motion",
        "Vocal Cord Dysfunction"
      ],
      "interventions": [
        {
          "name": "Carbon Dioxide",
          "type": "DRUG"
        },
        {
          "name": "Mechano-acoustic device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "26 Years",
        "sex": "ALL",
        "summary": "18 Years to 26 Years"
      },
      "enrollment_count": 130,
      "start_date": "2026-08-12",
      "completion_date": "2032-01-20",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-09-25T06:09:32.990Z",
      "location_count": 1,
      "location_summary": "Bloomington, Indiana",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07420530"
    },
    {
      "nct_id": "NCT00800228",
      "title": "Salt Study: Inhibited Breathing Pattern and Sodium Inhibitors in Sodium Sensitivity of Blood Pressure",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute on Aging (NIA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 96,
      "start_date": "2003-03",
      "completion_date": "2006-12",
      "has_results": false,
      "last_update_posted_date": "2008-12-02",
      "last_synced_at": "2026-09-25T06:09:32.990Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00800228"
    }
  ]
}