{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cardiovascular+effects&page=2",
    "query": {
      "intervention": "Cardiovascular effects",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cardiovascular+effects&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-15T00:22:48.878Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01921829",
      "title": "Protocolized Diuretic Strategy in Cardiorenal Failure",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cardiac Failure",
        "Renal Failure",
        "Kidney Failure"
      ],
      "interventions": [
        {
          "name": "Protocolized Diuretic Strategy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kelly V. Liang, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "21 Years and older · Male only"
      },
      "enrollment_count": 19,
      "start_date": "2013-11",
      "completion_date": "2015-11",
      "has_results": true,
      "last_update_posted_date": "2017-08-21",
      "last_synced_at": "2026-09-15T00:22:48.878Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01921829"
    },
    {
      "nct_id": "NCT00698139",
      "title": "Cardiovascular and Neurohormonal Effects of Faster Atrial Pacing Rate",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Medtronic Pacemaker",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 3,
      "start_date": "2011-04",
      "completion_date": "2012-09",
      "has_results": true,
      "last_update_posted_date": "2018-04-27",
      "last_synced_at": "2026-09-15T00:22:48.878Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00698139"
    },
    {
      "nct_id": "NCT01408680",
      "title": "CoQ10 Biomarker Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Oxidative Stress",
        "Inflammation",
        "Endothelial Dysfunction"
      ],
      "interventions": [
        {
          "name": "Coenzyme Q10",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 66,
      "start_date": "2011-11",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2014-12-04",
      "last_synced_at": "2026-09-15T00:22:48.878Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01408680"
    },
    {
      "nct_id": "NCT00246623",
      "title": "US Inhaled Insulin Dose Titration Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 2"
      ],
      "interventions": [
        {
          "name": "Exubera (inhaled insulin)",
          "type": "DRUG"
        },
        {
          "name": "8-point glucose diary (to assess pre- and post prandial glucoses)",
          "type": "PROCEDURE"
        },
        {
          "name": "Meal Tolerance Test",
          "type": "PROCEDURE"
        },
        {
          "name": "24-hour continuous glucose monitoring (at select sites)",
          "type": "PROCEDURE"
        },
        {
          "name": "Pulmonary Function Testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Hypoglycemic Event Monitoring",
          "type": "PROCEDURE"
        },
        {
          "name": "Laboratory Assessments",
          "type": "PROCEDURE"
        },
        {
          "name": "Nutritional Counseling and Diabetes Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 120,
      "start_date": "2005-11",
      "completion_date": "2007-03",
      "has_results": false,
      "last_update_posted_date": "2008-02-08",
      "last_synced_at": "2026-09-15T00:22:48.878Z",
      "location_count": 16,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • New Britain, Connecticut + 13 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "New Britain",
          "state": "Connecticut"
        },
        {
          "city": "Norwalk",
          "state": "Connecticut"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00246623"
    },
    {
      "nct_id": "NCT01175629",
      "title": "Veteran Health Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stress Disorders, Post-Traumatic",
        "Depression",
        "Diabetes",
        "Cardiovascular Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "MALE",
        "summary": "Male only"
      },
      "enrollment_count": 7568,
      "start_date": "2010-01",
      "completion_date": "2013-03",
      "has_results": false,
      "last_update_posted_date": "2014-07-02",
      "last_synced_at": "2026-09-15T00:22:48.878Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01175629"
    },
    {
      "nct_id": "NCT00640224",
      "title": "Insulin Resistance, Polycystic Ovary Syndrome, and Bone Research Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Polycystic Ovary Syndrome"
      ],
      "interventions": [
        {
          "name": "rosiglitazone",
          "type": "DRUG"
        },
        {
          "name": "drospirenone/ethinyl estradiol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Silva Arslanian",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "20 Years",
        "sex": "FEMALE",
        "summary": "10 Years to 20 Years · Female only"
      },
      "enrollment_count": 65,
      "start_date": "2005-03",
      "completion_date": "2015-07",
      "has_results": true,
      "last_update_posted_date": "2017-11-17",
      "last_synced_at": "2026-09-15T00:22:48.878Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00640224"
    },
    {
      "nct_id": "NCT00050765",
      "title": "Autologous Cultured Myoblasts (BioWhittaker) Transplanted Via Myocardial Injection",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Congestive Heart Failure",
        "Coronary Artery Disease",
        "Myocardial Infarction"
      ],
      "interventions": [
        {
          "name": "MyoCell™ Autologous Myoblasts",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bioheart, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 15,
      "start_date": "2006-08",
      "completion_date": "2006-08",
      "has_results": false,
      "last_update_posted_date": "2006-03-08",
      "last_synced_at": "2026-09-15T00:22:48.878Z",
      "location_count": 5,
      "location_summary": "Fort Lauderdale, Florida • Atlanta, Georgia • Chicago, Illinois + 2 more",
      "locations": [
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00050765"
    },
    {
      "nct_id": "NCT00526253",
      "title": "To Assess Safety and Efficacy of Myoblast Implantation Into Myocardium Post Myocardial Infarction",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Congestive Heart Failure"
      ],
      "interventions": [
        {
          "name": "MyoCell",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Hypothermosol",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "Bioheart, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 170,
      "start_date": "2007-09",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2017-07-21",
      "last_synced_at": "2026-09-15T00:22:48.878Z",
      "location_count": 33,
      "location_summary": "Birmingham, Alabama • Gilbert, Arizona • Phoenix, Arizona + 25 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00526253"
    },
    {
      "nct_id": "NCT01294267",
      "title": "Percutaneous Hemodynamic Support With Impella 2.5 During Scar-related Ventricular Tachycardia Ablation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventricular Tachycardia"
      ],
      "interventions": [
        {
          "name": "Circulatory Support System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vivek Reddy",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 20,
      "start_date": "2010-09",
      "completion_date": "2012-01",
      "has_results": true,
      "last_update_posted_date": "2018-02-14",
      "last_synced_at": "2026-09-15T00:22:48.878Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01294267"
    },
    {
      "nct_id": "NCT02611219",
      "title": "Deconditioning in Transplant",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Hematopoietic and Stem Cell Transplant"
      ],
      "interventions": [
        {
          "name": "General Health Module-Baseline Adolescent-Self Report (13-18 years)",
          "type": "OTHER"
        },
        {
          "name": "General Health Module-Follow Up Adolescent-Self Report (13-18 years)",
          "type": "OTHER"
        },
        {
          "name": "General Health Module-Baseline Parent Report-Adolescent (13-18 years)",
          "type": "OTHER"
        },
        {
          "name": "General Health Module-Follow Up Parent Report-Adolescent (13-18 years)",
          "type": "OTHER"
        },
        {
          "name": "General Health Module-Baseline Parent Report-School Age (5-12 years)",
          "type": "OTHER"
        },
        {
          "name": "General Health Module-Follow Up Parent Report-School Age (5-12 years)",
          "type": "OTHER"
        },
        {
          "name": "Demographic Data Form",
          "type": "OTHER"
        },
        {
          "name": "SCT Daily Activity Log",
          "type": "OTHER"
        },
        {
          "name": "The Functional Independence Measure for Children",
          "type": "OTHER"
        },
        {
          "name": "Manual Muscle Testing",
          "type": "OTHER"
        },
        {
          "name": "3-Minute Step Test",
          "type": "OTHER"
        },
        {
          "name": "HSCT Module-Follow Up Adolescent-Self Report (13-18 years)",
          "type": "OTHER"
        },
        {
          "name": "HSCT Module-Follow Child-Self Report (5-12 years)",
          "type": "OTHER"
        },
        {
          "name": "HSCT Module-Follow Up Parent Report-adolescent (13-18 years)",
          "type": "OTHER"
        },
        {
          "name": "HSCT Module-Follow Up Parent Report-School Age (5-12 years)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "7 Years to 17 Years"
      },
      "enrollment_count": 30,
      "start_date": "2015-03",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-05-27",
      "last_synced_at": "2026-09-15T00:22:48.878Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02611219"
    }
  ]
}