{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cerebral+Spinal+Fluid+collection&page=2", "query": { "intervention": "Cerebral Spinal Fluid collection", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 43, "total_pages": 5, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cerebral+Spinal+Fluid+collection&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cerebral+Spinal+Fluid+collection&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-30T08:53:38.992Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05419076", "title": "A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Lung Cancer", "Lung Cancer Metastatic", "Brain Metastases", "Brain Metastases, Adult", "Small-cell Lung Cancer", "Small Cell Lung Carcinoma" ], "interventions": [ { "name": "Stereotactic Radiosurgery", "type": "RADIATION" }, { "name": "Cerebrospinal fluid collection", "type": "PROCEDURE" } ], "intervention_types": [ "RADIATION", "PROCEDURE" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 62, "start_date": "2022-06-10", "completion_date": "2027-06-10", "has_results": false, "last_update_posted_date": "2026-06-10", "last_synced_at": "2026-09-30T08:53:38.992Z", "location_count": 7, "location_summary": "Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more", "locations": [ { "city": "Basking Ridge", "state": "New Jersey" }, { "city": "Middletown", "state": "New Jersey" }, { "city": "Montvale", "state": "New Jersey" }, { "city": "Commack", "state": "New York" }, { "city": "Harrison", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05419076" }, { "nct_id": "NCT06518057", "title": "Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Anatomic Stage IV Breast Cancer AJCC v8", "Metastatic Breast Carcinoma", "Metastatic Lung Non-Small Cell Carcinoma", "Metastatic Malignant Neoplasm in the Leptomeninges", "Stage IV Lung Cancer AJCC v8" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Electronic Health Record Review", "type": "OTHER" }, { "name": "Lumbar Puncture", "type": "PROCEDURE" }, { "name": "Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Positron Emission Tomography", "type": "PROCEDURE" }, { "name": "Proton Beam Craniospinal Irradiation", "type": "RADIATION" }, { "name": "Survey Administration", "type": "OTHER" }, { "name": "Volume Modulated Arc Therapy", "type": "RADIATION" }, { "name": "Hippocampal-Avoidance Craniospinal Irradiation", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "OTHER", "RADIATION" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 22, "start_date": "2025-03-03", "completion_date": "2028-07-01", "has_results": false, "last_update_posted_date": "2026-08-14", "last_synced_at": "2026-09-30T08:53:38.992Z", "location_count": 3, "location_summary": "San Francisco, California • New York, New York • Seattle, Washington", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "New York", "state": "New York" }, { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT06518057" }, { "nct_id": "NCT07619534", "title": "Collection of CSF Samples From Participants With Metastatic Triple Negative Breast Cancer (TNBC) and HER2+ Breast Cancer With no Prior History Nor Active Radiographically Detectable Brain Metastases", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Breast Cancer", "Breast Carcinoma", "Cancer of the Breast", "Malignant Neoplasm of Breast" ], "interventions": [ { "name": "Arm 1", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "18 Years to 120 Years" }, "enrollment_count": 139, "start_date": "2026-10-04", "completion_date": "2034-07-01", "has_results": false, "last_update_posted_date": "2026-09-29", "last_synced_at": "2026-09-30T08:53:38.992Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT07619534" }, { "nct_id": "NCT05620914", "title": "A Window of Opportunity Study of Patritumab Deruxtecan in Patients With Brain Metastases", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Brain Metastases, Adult" ], "interventions": [ { "name": "Patritumab deruxtecan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mustafa Khasraw, MBChB, MD, FRCP, FRACP", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2025-07", "completion_date": "2027-04", "has_results": false, "last_update_posted_date": "2025-06-15", "last_synced_at": "2026-09-30T08:53:38.992Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05620914" }, { "nct_id": "NCT05009992", "title": "Combination Therapy for the Treatment of Diffuse Midline Gliomas", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diffuse Intrinsic Pontine Glioma", "Diffuse Midline Glioma, H3 K27M-Mutant", "Recurrent Diffuse Intrinsic Pontine Glioma", "Recurrent Diffuse Midline Glioma, H3 K27M-Mutant", "Recurrent WHO Grade III Glioma", "WHO Grade III Glioma" ], "interventions": [ { "name": "ONC201", "type": "DRUG" }, { "name": "Radiation Therapy", "type": "RADIATION" }, { "name": "Paxalisib", "type": "DRUG" }, { "name": "DNX-2401", "type": "DRUG" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Years", "maximum_age": "39 Years", "sex": "ALL", "summary": "2 Years to 39 Years" }, "enrollment_count": 360, "start_date": "2021-10-20", "completion_date": "2029-06-30", "has_results": false, "last_update_posted_date": "2026-06-26", "last_synced_at": "2026-09-30T08:53:38.992Z", "location_count": 19, "location_summary": "Birmingham, Alabama • Los Angeles, California • San Diego, California + 16 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT05009992" }, { "nct_id": "NCT01556178", "title": "Blood and Cerebrospinal Fluid for Pediatric Brain Tumor Research", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hydrocephalus" ], "interventions": [], "intervention_types": [], "sponsor": "Ann & Robert H Lurie Children's Hospital of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "21 Years", "sex": "ALL", "summary": "1 Year to 21 Years" }, "enrollment_count": 5, "start_date": "2011-07", "completion_date": "2012-04", "has_results": false, "last_update_posted_date": "2016-02-05", "last_synced_at": "2026-09-30T08:53:38.992Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01556178" }, { "nct_id": "NCT05854433", "title": "Brain Structure and Clinical Endpoints in Myotonic Dystrophy Type 2", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Myotonic Dystrophy Type 2", "Myotonic Dystrophy Type 1" ], "interventions": [ { "name": "Non-interventional study", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "30 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "30 Years to 65 Years" }, "enrollment_count": 100, "start_date": "2023-04-26", "completion_date": "2027-06", "has_results": false, "last_update_posted_date": "2026-07-14", "last_synced_at": "2026-09-30T08:53:38.992Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05854433" }, { "nct_id": "NCT02058953", "title": "CNS and Extracranial Tumor Tissues, CSF, and Blood From Patients With Melanoma Brain Metastases", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Melanoma", "Brain Metastases" ], "interventions": [ { "name": "Craniotomy scheduled", "type": "PROCEDURE" }, { "name": "Collection for non-craniotomy", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "University of Pittsburgh", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 7, "start_date": "2014-08-12", "completion_date": "2019-08-19", "has_results": false, "last_update_posted_date": "2019-10-04", "last_synced_at": "2026-09-30T08:53:38.992Z", "location_count": 2, "location_summary": "Pittsburgh, Pennsylvania • Houston, Texas", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02058953" }, { "nct_id": "NCT07494812", "title": "Examining the Feasibility of Using Pressure Gradient Regulated Automated Cerebral Spinal Fluid Drainage During External Lumbar Drain Trials", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "NPH (Normal Pressure Hydrocephalus)" ], "interventions": [ { "name": "Intellidrop Automated CSF Drainage System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "60 Years to 99 Years" }, "enrollment_count": 10, "start_date": "2026-05-14", "completion_date": "2026-10-31", "has_results": false, "last_update_posted_date": "2026-06-02", "last_synced_at": "2026-09-30T08:53:38.992Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07494812" }, { "nct_id": "NCT05378659", "title": "Neuroinflammation and Alzheimer's Pathology in POCD", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Post-Operative Confusion", "Neuroinflammatory Response", "Alzheimer Disease" ], "interventions": [ { "name": "Montreal Cognitive Assessment", "type": "BEHAVIORAL" }, { "name": "Stroop Test", "type": "BEHAVIORAL" }, { "name": "4AT Delirium", "type": "DIAGNOSTIC_TEST" }, { "name": "Grooved Pegboard", "type": "BEHAVIORAL" }, { "name": "NACC Cognitive Battery", "type": "BEHAVIORAL" }, { "name": "ERP Testing", "type": "DIAGNOSTIC_TEST" }, { "name": "Blood Plasma and Serum sampling", "type": "DIAGNOSTIC_TEST" }, { "name": "Cerebral Spinal Fluid Sample", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "BEHAVIORAL", "DIAGNOSTIC_TEST" ], "sponsor": "University of Tennessee Graduate School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 120, "start_date": "2021-11-01", "completion_date": "2022-09-30", "has_results": false, "last_update_posted_date": "2022-05-18", "last_synced_at": "2026-09-30T08:53:38.992Z", "location_count": 1, "location_summary": "Knoxville, Tennessee", "locations": [ { "city": "Knoxville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT05378659" } ] }