{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cetylpyridinium+Chloride+%28CPC%29",
    "query": {
      "intervention": "Cetylpyridinium Chloride (CPC)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cetylpyridinium+Chloride+%28CPC%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-02T00:36:35.103Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03026205",
      "title": "ARMS-I (a Formulation of Cetylpyridinium Chloride -CPC)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Viral Upper Respiratory Tract Infection"
      ],
      "interventions": [
        {
          "name": "ARMS-I",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Toledo Health Science Campus",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 0,
      "start_date": "2017-01",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2019-04-17",
      "last_synced_at": "2026-10-02T00:36:35.103Z",
      "location_count": 1,
      "location_summary": "Toledo, Ohio",
      "locations": [
        {
          "city": "Toledo",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03026205"
    },
    {
      "nct_id": "NCT07211061",
      "title": "A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment Methods",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Stannous Fluoride Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Sodium Fluoride Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "electric toothbrush",
          "type": "DEVICE"
        },
        {
          "name": "Cetylpyridinium Chloride (CPC)",
          "type": "DRUG"
        },
        {
          "name": "manual toothbrush",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Procter and Gamble",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 69,
      "start_date": "2011-09-21",
      "completion_date": "2011-11-10",
      "has_results": false,
      "last_update_posted_date": "2025-10-07",
      "last_synced_at": "2026-10-02T00:36:35.103Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07211061"
    },
    {
      "nct_id": "NCT07619729",
      "title": "Evaluate the Efficacy of an Oral Health Behavioral Intervention in People With Diabetes",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetes Type 2",
        "Periodontal Disease",
        "Caries"
      ],
      "interventions": [
        {
          "name": "Diabetes Oral Health Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stannous Fluoride Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Cetylpyridinium Chloride (CPC) and Zinc Lactate Mouthwash",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10000,
      "start_date": "2026-05-26",
      "completion_date": "2028-01-02",
      "has_results": false,
      "last_update_posted_date": "2026-09-03",
      "last_synced_at": "2026-10-02T00:36:35.103Z",
      "location_count": 1,
      "location_summary": "Long Island City, New York",
      "locations": [
        {
          "city": "Long Island City",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07619729"
    },
    {
      "nct_id": "NCT07398846",
      "title": "Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Plaque"
      ],
      "interventions": [
        {
          "name": "0.454%Stannous fluoride toothpaste",
          "type": "DRUG"
        },
        {
          "name": "0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe",
          "type": "DRUG"
        },
        {
          "name": "0.76% Sodium Monofluorophosphate (Na MFP) toothpaste",
          "type": "DRUG"
        },
        {
          "name": "0.022% Sodium Fluoride mouthwash",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 134,
      "start_date": "2026-01-26",
      "completion_date": "2026-04-29",
      "has_results": false,
      "last_update_posted_date": "2026-05-22",
      "last_synced_at": "2026-10-02T00:36:35.103Z",
      "location_count": 1,
      "location_summary": "Melbourne, Florida",
      "locations": [
        {
          "city": "Melbourne",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07398846"
    },
    {
      "nct_id": "NCT04931004",
      "title": "Oral Rinse to Reduced Expelled Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) During COVID-19 Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Covid19"
      ],
      "interventions": [
        {
          "name": "Mouthwash Product",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2021-07-21",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-10-02T00:36:35.103Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04931004"
    },
    {
      "nct_id": "NCT01877421",
      "title": "Safety and Tolerability of Antiplaque Chewing Gum in a Gingivitis Population",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Plaque",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "2 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "4 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "6 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "10 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "20 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "30 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "50 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "75 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "100 mg KSL-W",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "U.S. Army Medical Research and Development Command",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 135,
      "start_date": "2014-02-25",
      "completion_date": "2016-03",
      "has_results": true,
      "last_update_posted_date": "2020-02-13",
      "last_synced_at": "2026-10-02T00:36:35.103Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01877421"
    },
    {
      "nct_id": "NCT03219840",
      "title": "Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gingivitis",
        "Plaque, Dental",
        "Periodontal Diseases"
      ],
      "interventions": [
        {
          "name": "Cetylpyridinium Chloride (CPC) 0.09% + Xylitol chewing gum",
          "type": "DRUG"
        },
        {
          "name": "Xylitol only chewing gum",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2017-10-18",
      "completion_date": "2018-09-08",
      "has_results": true,
      "last_update_posted_date": "2021-02-08",
      "last_synced_at": "2026-10-02T00:36:35.103Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03219840"
    },
    {
      "nct_id": "NCT00855933",
      "title": "A Controlled Clinical Study to Determine the Gingivitis Benefit of Flossing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Experimental Floss",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Procter and Gamble",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2009-01",
      "completion_date": "2009-02",
      "has_results": true,
      "last_update_posted_date": "2013-02-08",
      "last_synced_at": "2026-10-02T00:36:35.103Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00855933"
    },
    {
      "nct_id": "NCT01695187",
      "title": "NB-001 Treatment of Recurrent Herpes Labialis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Herpes Labialis"
      ],
      "interventions": [
        {
          "name": "NB-001 (0.3%)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NanoBio Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 362,
      "start_date": "2012-10",
      "completion_date": "2013-07",
      "has_results": false,
      "last_update_posted_date": "2013-06-14",
      "last_synced_at": "2026-10-02T00:36:35.103Z",
      "location_count": 12,
      "location_summary": "Chandler, Arizona • Tucson, Arizona • Chicago, Illinois + 9 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Edina",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01695187"
    },
    {
      "nct_id": "NCT06660069",
      "title": "A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Plaque",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste)",
          "type": "DRUG"
        },
        {
          "name": "CPC Mouthwash (Parodontax Active Gum Health Mouthwash)",
          "type": "DRUG"
        },
        {
          "name": "Regular Fluoride Toothpaste (Crest Cavity Protection)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 199,
      "start_date": "2024-11-18",
      "completion_date": "2025-03-11",
      "has_results": true,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-10-02T00:36:35.103Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06660069"
    }
  ]
}