{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Challenge%21",
    "query": {
      "intervention": "Challenge!"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 1522,
    "total_pages": 153,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Challenge%21&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T13:28:57.279Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03915587",
      "title": "Bedside Resources to Gauge Intravascular Volume Status",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypovolemia",
        "Craniosynostoses"
      ],
      "interventions": [
        {
          "name": "CardioQ-EDM and CipherOx-CRI",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "3 Months to 2 Years"
      },
      "enrollment_count": 23,
      "start_date": "2019-04-08",
      "completion_date": "2020-03-12",
      "has_results": true,
      "last_update_posted_date": "2023-06-29",
      "last_synced_at": "2026-09-03T13:28:57.279Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03915587"
    },
    {
      "nct_id": "NCT03221517",
      "title": "Mapping the Shift Worker's Microbiome",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Standardized meal with a glucose challenge test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "59 Years",
        "sex": "MALE",
        "summary": "40 Years to 59 Years · Male only"
      },
      "enrollment_count": 12,
      "start_date": "2017-09-27",
      "completion_date": "2028-11",
      "has_results": false,
      "last_update_posted_date": "2026-01-23",
      "last_synced_at": "2026-09-03T13:28:57.279Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03221517"
    },
    {
      "nct_id": "NCT04498143",
      "title": "Single-Session Intervention Targeting Self-Injurious Behavior in Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nonsuicidal Self Injury",
        "Self Hatred",
        "Suicidal Thoughts",
        "Suicide Attempts"
      ],
      "interventions": [
        {
          "name": "Project SAVE (\"Stop Adolescent Violence Everywhere\") SSI",
          "type": "OTHER"
        },
        {
          "name": "Active Comparator: Supportive Therapy (\"Share Your Feelings\") SSI",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "13 Years to 16 Years"
      },
      "enrollment_count": 565,
      "start_date": "2020-08-18",
      "completion_date": "2021-04-14",
      "has_results": true,
      "last_update_posted_date": "2024-12-10",
      "last_synced_at": "2026-09-03T13:28:57.279Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04498143"
    },
    {
      "nct_id": "NCT06494891",
      "title": "Motivation for IV Alcohol Self-Administration in Humans",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alcohol Use Disorder"
      ],
      "interventions": [
        {
          "name": "Intravenous Alcohol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 210,
      "start_date": "2024-01-16",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-09-03T13:28:57.279Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06494891"
    },
    {
      "nct_id": "NCT00542113",
      "title": "Diabetes Virtual Trek: Obesity and Diabetes Prevention Through Science Enrichment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "DvtProgram ENERGY",
          "type": "BEHAVIORAL"
        },
        {
          "name": "DvtProgramENERGY",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Colorado State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "13 Years",
        "sex": "ALL",
        "summary": "6 Years to 13 Years"
      },
      "enrollment_count": 1703,
      "start_date": "2001-09",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2014-11-07",
      "last_synced_at": "2026-09-03T13:28:57.279Z",
      "location_count": 2,
      "location_summary": "Cortez, Colorado • Fort Collins, Colorado",
      "locations": [
        {
          "city": "Cortez",
          "state": "Colorado"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00542113"
    },
    {
      "nct_id": "NCT03521180",
      "title": "A Study to Evaluate Gluten Challenge on Immune Responses in Subjects With Celiac Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Celiac Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Celgene",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 5,
      "start_date": "2018-05-11",
      "completion_date": "2019-07-18",
      "has_results": false,
      "last_update_posted_date": "2020-02-26",
      "last_synced_at": "2026-09-03T13:28:57.279Z",
      "location_count": 2,
      "location_summary": "Dallas, Texas • Seattle, Washington",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03521180"
    },
    {
      "nct_id": "NCT05765903",
      "title": "UM CRMC RecuR Score Pilot",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patient Readmission",
        "Pulmonary Disease, Chronic Obstructive",
        "Heart Failure",
        "Diabetes Mellitus Poor Control",
        "Hypertension",
        "Pneumonia"
      ],
      "interventions": [
        {
          "name": "Standard of Care",
          "type": "OTHER"
        },
        {
          "name": "Enhanced Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2024-03-31",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2024-02-15",
      "last_synced_at": "2026-09-03T13:28:57.279Z",
      "location_count": 1,
      "location_summary": "La Plata, Maryland",
      "locations": [
        {
          "city": "La Plata",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05765903"
    },
    {
      "nct_id": "NCT04083950",
      "title": "Induction of Gut Permeability by an Oral Vaccine",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Intestinal Permeability",
        "Inflammation",
        "Vaccine",
        "Typhoid Fever"
      ],
      "interventions": [
        {
          "name": "Vivotif Typhoid Oral Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Aspirin (Positive Control)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "USDA, Western Human Nutrition Research Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 49 Years · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2019-12-04",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-11-24",
      "last_synced_at": "2026-09-03T13:28:57.279Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04083950"
    },
    {
      "nct_id": "NCT04851340",
      "title": "Investigating the Detection of Bovine and Soy Proteins in Human Milk",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Microbiome",
        "Stress",
        "Food Allergy in Infants"
      ],
      "interventions": [
        {
          "name": "Cow's Milk",
          "type": "OTHER"
        },
        {
          "name": "Soy Milk",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Idaho",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 38,
      "start_date": "2020-11-09",
      "completion_date": "2021-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-01-24",
      "last_synced_at": "2026-09-03T13:28:57.279Z",
      "location_count": 1,
      "location_summary": "Moscow, Idaho",
      "locations": [
        {
          "city": "Moscow",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04851340"
    },
    {
      "nct_id": "NCT05849259",
      "title": "Caring for Caregivers and People Living With Dementia Under Home-Based Primary Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia",
        "Quality of Life",
        "Caregiver Stress"
      ],
      "interventions": [
        {
          "name": "Dementia Care Quality at Home",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2023-10-16",
      "completion_date": "2024-12-20",
      "has_results": true,
      "last_update_posted_date": "2025-09-25",
      "last_synced_at": "2026-09-03T13:28:57.279Z",
      "location_count": 2,
      "location_summary": "Honolulu, Hawaii • Richmond, Virginia",
      "locations": [
        {
          "city": "Honolulu",
          "state": "Hawaii"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05849259"
    }
  ]
}