{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Challenge&page=10",
    "query": {
      "intervention": "Challenge",
      "page": 10
    },
    "page_size": 10
  },
  "pagination": {
    "page": 10,
    "page_size": 10,
    "total_count": 1538,
    "total_pages": 154,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Challenge&page=11&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Challenge&page=9&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-22T23:58:44.384Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01390259",
      "title": "Hypoglycemia Prevention After Exercise in Adolescent T1DM Patients Using a Control to Range System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 1 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Open-Loop",
          "type": "DEVICE"
        },
        {
          "name": "Closed-Loop",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 11,
      "start_date": "2010-01",
      "completion_date": "2011-02",
      "has_results": true,
      "last_update_posted_date": "2014-08-15",
      "last_synced_at": "2026-10-22T23:58:44.384Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01390259"
    },
    {
      "nct_id": "NCT05721482",
      "title": "Stress and Hypertension in Dementia Caregivers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Stress, Psychological"
      ],
      "interventions": [
        {
          "name": "Caregiver Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "40 Years and older · Female only"
      },
      "enrollment_count": 28,
      "start_date": "2023-01-17",
      "completion_date": "2025-09-02",
      "has_results": true,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-10-22T23:58:44.384Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05721482"
    },
    {
      "nct_id": "NCT04690582",
      "title": "Improving Treatment Outcomes for Suicidal Veterans With PTSD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Suicidal Ideation",
        "Suicide, Attempted",
        "Ptsd"
      ],
      "interventions": [
        {
          "name": "Cognitive Processing Therapy (CPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Crisis Response Plan (CRP)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Safety Planning Intervention (SPI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Narrative Assessment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 157,
      "start_date": "2021-01-15",
      "completion_date": "2023-12-31",
      "has_results": true,
      "last_update_posted_date": "2024-12-20",
      "last_synced_at": "2026-10-22T23:58:44.384Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04690582"
    },
    {
      "nct_id": "NCT01540396",
      "title": "Gestational Diabetes Diagnostic Methods",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gestational Diabetes"
      ],
      "interventions": [
        {
          "name": "Dietary modification and medications",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 47,
      "start_date": "2012-02",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2016-02-04",
      "last_synced_at": "2026-10-22T23:58:44.384Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01540396"
    },
    {
      "nct_id": "NCT03644082",
      "title": "Computerized Cognitive Training for Patients With Epilepsy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epilepsy"
      ],
      "interventions": [
        {
          "name": "Luminosity Trial Memory Match",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Luminosity Trial Memory Matrix",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Luminosity Trial Famliar Faces",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Luminosity Trial Brain Shift",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Luminosity Trial Star Search",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Luminosity Trial Word Bubbles",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Luminosity Trial Color Match",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Luminosity Trial Ebb and Flow",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Luminosity TrialChalk Board Challenge",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Luminosiuty Follow that Frog",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Luminosity Train of Thought",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 0,
      "start_date": "2020-12",
      "completion_date": "2021-04-30",
      "has_results": false,
      "last_update_posted_date": "2021-07-01",
      "last_synced_at": "2026-10-22T23:58:44.384Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03644082"
    },
    {
      "nct_id": "NCT00870896",
      "title": "The Effects of Tiotropium on the Cough Reflex in Patients With Chronic Obstructive Pulmonary Disease (COPD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease",
        "Chronic Bronchitis"
      ],
      "interventions": [
        {
          "name": "Tiotropium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "ThomasTruncale",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "MALE",
        "summary": "40 Years to 80 Years · Male only"
      },
      "enrollment_count": 5,
      "start_date": "2008-02",
      "completion_date": "2012-06",
      "has_results": true,
      "last_update_posted_date": "2014-10-01",
      "last_synced_at": "2026-10-22T23:58:44.384Z",
      "location_count": 2,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00870896"
    },
    {
      "nct_id": "NCT03162614",
      "title": "Efficacy, Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Evaluating Different Dose Schedules in a Sporozoite Challenge Model in Healthy Malaria-naïve Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Malaria"
      ],
      "interventions": [
        {
          "name": "RTS,S/AS01E",
          "type": "BIOLOGICAL"
        },
        {
          "name": "RTS,S/AS01B",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Sporozoite-infected mosquitoes challenge.",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 154,
      "start_date": "2017-05-24",
      "completion_date": "2018-09-24",
      "has_results": true,
      "last_update_posted_date": "2020-10-27",
      "last_synced_at": "2026-10-22T23:58:44.384Z",
      "location_count": 1,
      "location_summary": "Silver Spring, Maryland",
      "locations": [
        {
          "city": "Silver Spring",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03162614"
    },
    {
      "nct_id": "NCT04870138",
      "title": "Experimental Human Infection With Neisseria Gonorrhoeae (LptA Trial)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Gonococcal Infection"
      ],
      "interventions": [
        {
          "name": "Azithromycin",
          "type": "DRUG"
        },
        {
          "name": "Ceftriaxone",
          "type": "DRUG"
        },
        {
          "name": "Ciprofloxacin",
          "type": "DRUG"
        },
        {
          "name": "Neisseria gonorrhoeae strain FA1090 A26",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Neisseria gonorrhoeae strain FA7527",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BIOLOGICAL"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "MALE",
        "summary": "18 Years to 35 Years · Male only"
      },
      "enrollment_count": 16,
      "start_date": "2013-03-10",
      "completion_date": "2015-04-28",
      "has_results": true,
      "last_update_posted_date": "2021-12-02",
      "last_synced_at": "2026-10-22T23:58:44.384Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04870138"
    },
    {
      "nct_id": "NCT06916221",
      "title": "BID LTM Digital Intervention in Aging",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Long-Term Memory",
        "Inhibitory Control",
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Long Term Memory",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Worder",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "60 Years to 85 Years"
      },
      "enrollment_count": 150,
      "start_date": "2025-08-20",
      "completion_date": "2028-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-02",
      "last_synced_at": "2026-10-22T23:58:44.384Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06916221"
    },
    {
      "nct_id": "NCT03153449",
      "title": "ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty Population",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Primary Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "ATTUNE Revision Knee System in Total Knee Arthroplasty",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "22 Years to 80 Years"
      },
      "enrollment_count": 400,
      "start_date": "2017-09-19",
      "completion_date": "2030-10-17",
      "has_results": false,
      "last_update_posted_date": "2026-09-25",
      "last_synced_at": "2026-10-22T23:58:44.384Z",
      "location_count": 15,
      "location_summary": "San Diego, California • Denver, Colorado • Fort Collins, Colorado + 12 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        },
        {
          "city": "Niantic",
          "state": "Connecticut"
        },
        {
          "city": "DeLand",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03153449"
    }
  ]
}