{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cig",
    "query": {
      "intervention": "Cig"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 39,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cig&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T14:36:37.627Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04898075",
      "title": "Quit Nicotine: E-Cig Cessation Intervention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "E-Cig Use"
      ],
      "interventions": [
        {
          "name": "Remote Contingency Management (CM) for nicotine abstinence",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "13 Years to 20 Years"
      },
      "enrollment_count": 108,
      "start_date": "2021-04-01",
      "completion_date": "2025-01-10",
      "has_results": false,
      "last_update_posted_date": "2025-03-10",
      "last_synced_at": "2026-09-05T14:36:37.627Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04898075"
    },
    {
      "nct_id": "NCT03823885",
      "title": "ECigs, Inflammation and Oxidative Stress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "E-cigarettes, Oxidative Stress, Inflammation"
      ],
      "interventions": [
        {
          "name": "e-cigarette",
          "type": "OTHER"
        },
        {
          "name": "empty (-cigarette sham control)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 148,
      "start_date": "2019-02-08",
      "completion_date": "2023-10-01",
      "has_results": false,
      "last_update_posted_date": "2023-10-04",
      "last_synced_at": "2026-09-05T14:36:37.627Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03823885"
    },
    {
      "nct_id": "NCT03453385",
      "title": "Clinical Outcomes of a Nationwide, Naturalistic E-Cig Trial (CONNECT)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Electronic Cigarette",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 638,
      "start_date": "2018-05-24",
      "completion_date": "2022-09-08",
      "has_results": true,
      "last_update_posted_date": "2023-09-11",
      "last_synced_at": "2026-09-05T14:36:37.627Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03453385"
    },
    {
      "nct_id": "NCT03023397",
      "title": "Evaluation of the Effect of a Nasal Allergen Challenge With Dermatophagoides Farinae Extract on Nasal Airway Inflammation in Allergic Individuals, Comparing E-cigarette Users to Cigarette Smokers and Non-smokers.",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy Participants",
        "Tobacco Smokers"
      ],
      "interventions": [
        {
          "name": "Der f",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 12,
      "start_date": "2017-03-27",
      "completion_date": "2018-04-23",
      "has_results": true,
      "last_update_posted_date": "2021-06-04",
      "last_synced_at": "2026-09-05T14:36:37.627Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03023397"
    },
    {
      "nct_id": "NCT05432830",
      "title": "Sex Differences in E-cig Perception: Study 1",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Addiction",
        "E-Cig Use",
        "Cigarette Smoking",
        "Sex Differences"
      ],
      "interventions": [
        {
          "name": "E-liquid Flavor 1",
          "type": "OTHER"
        },
        {
          "name": "E-liquid Flavor 2",
          "type": "OTHER"
        },
        {
          "name": "E-liquid Flavor 3",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "44 Years",
        "sex": "ALL",
        "summary": "21 Years to 44 Years"
      },
      "enrollment_count": 66,
      "start_date": "2024-04-30",
      "completion_date": "2025-07-18",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-09-05T14:36:37.627Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05432830"
    },
    {
      "nct_id": "NCT03449017",
      "title": "Reactions to E-cigs and Alcohol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Abuse",
        "Nicotine Dependence Tobacco Product"
      ],
      "interventions": [
        {
          "name": "E-cig use",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2017-03-24",
      "completion_date": "2018-11-11",
      "has_results": false,
      "last_update_posted_date": "2018-11-29",
      "last_synced_at": "2026-09-05T14:36:37.627Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03449017"
    },
    {
      "nct_id": "NCT04843501",
      "title": "Middle School Cluster Randomized Controlled Trial (RCT) to Evaluate E-Cigarette Prevention Program: CATCH My Breath",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "E-cigarette Use"
      ],
      "interventions": [
        {
          "name": "CATCH My Breath (CMB) program for E-cigarette prevention among adolescents",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Texas Education Agency (TEA) required tobacco prevention program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "10 Years to 15 Years"
      },
      "enrollment_count": 2059,
      "start_date": "2020-12-13",
      "completion_date": "2024-12-30",
      "has_results": true,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-09-05T14:36:37.627Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04843501"
    },
    {
      "nct_id": "NCT05383508",
      "title": "Nicotine Pharmacokinetics Following Use of the P4M3 Gen 2.0 E-Cigarette Compared to Smoking Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Vaping",
        "Nicotine",
        "Vaping"
      ],
      "interventions": [
        {
          "name": "CA35",
          "type": "OTHER"
        },
        {
          "name": "CM35",
          "type": "OTHER"
        },
        {
          "name": "Cig",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Philip Morris Products S.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "24 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "24 Years to 65 Years"
      },
      "enrollment_count": 36,
      "start_date": "2022-04-28",
      "completion_date": "2022-08-25",
      "has_results": true,
      "last_update_posted_date": "2024-04-26",
      "last_synced_at": "2026-09-05T14:36:37.627Z",
      "location_count": 1,
      "location_summary": "High Point, North Carolina",
      "locations": [
        {
          "city": "High Point",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05383508"
    },
    {
      "nct_id": "NCT03839745",
      "title": "Short-Term Cardiovascular Effects of E-Cigarettes: Influence of Device Power",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Risk Factor",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Electronic Cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2019-03-26",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-07-01",
      "last_synced_at": "2026-09-05T14:36:37.627Z",
      "location_count": 2,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03839745"
    },
    {
      "nct_id": "NCT06105424",
      "title": "BRP1602: Evaluation of Technical and Logistical Feasibility to Measure Lung Permeability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use",
        "Smoking",
        "Smoking, Tobacco"
      ],
      "interventions": [
        {
          "name": "Lung Permeability Assessment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "RAI Services Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "30 Years to 50 Years"
      },
      "enrollment_count": 21,
      "start_date": "2016-09-24",
      "completion_date": "2016-12-28",
      "has_results": false,
      "last_update_posted_date": "2023-10-27",
      "last_synced_at": "2026-09-05T14:36:37.627Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06105424"
    }
  ]
}