{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Clonidine+Pill", "query": { "intervention": "Clonidine Pill" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-03T09:21:28.890Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03109795", "title": "Anxiety-mediated Impairments in Large Elastic Artery Function and the Autonomic Nervous System", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Anxiety", "Hypertension" ], "interventions": [ { "name": "Clonidine Pill", "type": "DRUG" }, { "name": "Hydrochlorothiazide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Iowa", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "18 Years to 79 Years" }, "enrollment_count": 35, "start_date": "2017-04-10", "completion_date": "2023-06-30", "has_results": true, "last_update_posted_date": "2024-07-29", "last_synced_at": "2026-09-03T09:21:28.890Z", "location_count": 1, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT03109795" }, { "nct_id": "NCT04030572", "title": "Feasibility of Administering Clonidine as a Pharmacological Challenge in Imaging Studies", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Neuro-Degenerative Disease", "Cancer" ], "interventions": [ { "name": "Clonidine Pill", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Weill Medical College of Cornell University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "89 Years", "sex": "ALL", "summary": "18 Years to 89 Years" }, "enrollment_count": 3, "start_date": "2019-12-10", "completion_date": "2020-03-17", "has_results": false, "last_update_posted_date": "2021-06-24", "last_synced_at": "2026-09-03T09:21:28.890Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04030572" }, { "nct_id": "NCT00223717", "title": "Treatment of Supine Hypertension in Autonomic Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Clonidine", "type": "DRUG" }, { "name": "Nitroglycerin transdermal", "type": "DRUG" }, { "name": "Dipyridamole/ Aspirin (Aggrenox)", "type": "DRUG" }, { "name": "Desmopressin (DDAVP)", "type": "DRUG" }, { "name": "Sildenafil", "type": "DRUG" }, { "name": "Nifedipine", "type": "DRUG" }, { "name": "Hydralazine", "type": "DRUG" }, { "name": "Hydrochlorothiazide", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Bosentan", "type": "DRUG" }, { "name": "Diltiazem", "type": "DRUG" }, { "name": "Eplerenone", "type": "DRUG" }, { "name": "guanfacine", "type": "DRUG" }, { "name": "L-arginine", "type": "DIETARY_SUPPLEMENT" }, { "name": "captopril", "type": "DRUG" }, { "name": "carbidopa", "type": "DRUG" }, { "name": "losartan", "type": "DRUG" }, { "name": "metoprolol tartrate", "type": "DRUG" }, { "name": "nebivolol hydrochloride", "type": "DRUG" }, { "name": "prazosin hydrochloride", "type": "DRUG" }, { "name": "tamsulosin hydrochloride", "type": "DRUG" }, { "name": "Head-up tilt.", "type": "OTHER" }, { "name": "aliskiren", "type": "DRUG" }, { "name": "Local heat stress", "type": "OTHER" } ], "intervention_types": [ "DRUG", "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 152, "start_date": "2001-01", "completion_date": "2017-01", "has_results": false, "last_update_posted_date": "2017-10-13", "last_synced_at": "2026-09-03T09:21:28.890Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00223717" }, { "nct_id": "NCT04934228", "title": "Mitigating the Pro-inflammatory Phenotype of Obesity", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Blood Pressure", "Diabetes", "Obesity", "Insulin Resistance", "Diuretics Drug Reactions", "Sympathetic Nerve Activity" ], "interventions": [ { "name": "Hydrochlorothiazide 12.5Mg Tab", "type": "DRUG" }, { "name": "Clonidine Pill", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Kansas Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "18 Years to 79 Years" }, "enrollment_count": 60, "start_date": "2021-07-01", "completion_date": "2027-08-01", "has_results": false, "last_update_posted_date": "2025-06-05", "last_synced_at": "2026-09-03T09:21:28.890Z", "location_count": 1, "location_summary": "Kansas City, Kansas", "locations": [ { "city": "Kansas City", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04934228" }, { "nct_id": "NCT04032691", "title": "PET Study of a2a Agonist Effects on the Ventricular CSF Clearance of [11C]Butanol", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Healthy Volunteers" ], "interventions": [ { "name": "Clonidine Pill", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Weill Medical College of Cornell University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2019-08-27", "completion_date": "2021-05-24", "has_results": false, "last_update_posted_date": "2021-07-20", "last_synced_at": "2026-09-03T09:21:28.890Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04032691" }, { "nct_id": "NCT01112878", "title": "Oral Clonidine & Gabapentin: Improving Recovery and Pain Management After Outpatient With Major Orthopedic Surgery", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Shoulder Arthroscopy", "Knee Arthroscopy" ], "interventions": [ { "name": "Sugar pill", "type": "DRUG" }, { "name": "Gabapentin", "type": "DRUG" }, { "name": "Clonidine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cedars-Sinai Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 0, "start_date": "2015-06", "completion_date": "2015-06", "has_results": false, "last_update_posted_date": "2015-09-14", "last_synced_at": "2026-09-03T09:21:28.890Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01112878" }, { "nct_id": "NCT00884832", "title": "A Placebo-Controlled Study of Clonidine for Fecal Incontinence.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Fecal Incontinence" ], "interventions": [ { "name": "Clonidine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "FEMALE", "summary": "18 Years to 75 Years · Female only" }, "enrollment_count": 44, "start_date": "2008-10", "completion_date": "2012-08", "has_results": true, "last_update_posted_date": "2014-03-06", "last_synced_at": "2026-09-03T09:21:28.890Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00884832" }, { "nct_id": "NCT00262470", "title": "Treatment of Orthostatic Intolerance", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Tachycardia", "Chronic Orthostatic Intolerance" ], "interventions": [ { "name": "Acetazolamide", "type": "DRUG" }, { "name": "Atomoxetine", "type": "DRUG" }, { "name": "NO Drug", "type": "OTHER" }, { "name": "Clonidine", "type": "DRUG" }, { "name": "Entacapone", "type": "DRUG" }, { "name": "Entacapone & Propranolol", "type": "DRUG" }, { "name": "Atomoxetine & Propranolol", "type": "DRUG" }, { "name": "Indomethacin", "type": "DRUG" }, { "name": "Mecamylamine", "type": "DRUG" }, { "name": "Isosorbide Dinitrate", "type": "DRUG" }, { "name": "Melatonin", "type": "DIETARY_SUPPLEMENT" }, { "name": "Midodrine", "type": "DRUG" }, { "name": "Modafinil", "type": "DRUG" }, { "name": "Octreotide", "type": "DRUG" }, { "name": "Placebo", "type": "RADIATION" }, { "name": "Propranolol", "type": "DRUG" }, { "name": "Modafinil & Propranolol", "type": "DRUG" }, { "name": "Sertraline", "type": "DRUG" }, { "name": "IV Saline", "type": "PROCEDURE" }, { "name": "Drinking Water", "type": "OTHER" }, { "name": "Breathing Device", "type": "DEVICE" }, { "name": "memantine", "type": "DRUG" }, { "name": "Abdominal binder", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "OTHER", "DIETARY_SUPPLEMENT", "RADIATION", "PROCEDURE", "DEVICE" ], "sponsor": "Satish R. Raj", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 150, "start_date": "1997-04", "completion_date": "2029-12", "has_results": false, "last_update_posted_date": "2025-10-08", "last_synced_at": "2026-09-03T09:21:28.890Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00262470" }, { "nct_id": "NCT04877093", "title": "Repurposing Low-Dose Clonidine for PTSD in Veterans", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "PTSD", "Posttraumatic Stress Disorder", "Sleep" ], "interventions": [ { "name": "Clonidine Pill", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 32, "start_date": "2023-06-01", "completion_date": "2027-03-31", "has_results": false, "last_update_posted_date": "2026-03-31", "last_synced_at": "2026-09-03T09:21:28.890Z", "location_count": 1, "location_summary": "Wauwatosa, Wisconsin", "locations": [ { "city": "Wauwatosa", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT04877093" }, { "nct_id": "NCT02812368", "title": "Clonidine for Sleep Disturbances in Children With Autism Spectrum Disorder", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Autism Spectrum Disorder" ], "interventions": [ { "name": "Clonidine", "type": "DRUG" }, { "name": "Placebo (for clonidine)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ohio State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "14 Years", "sex": "ALL", "summary": "6 Years to 14 Years" }, "enrollment_count": 0, "start_date": "2016-08", "completion_date": "2017-01", "has_results": false, "last_update_posted_date": "2017-02-02", "last_synced_at": "2026-09-03T09:21:28.890Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02812368" } ] }