{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Closed+loop+with+sensor+and+Insulin",
    "query": {
      "intervention": "Closed loop with sensor and Insulin"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 56,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Closed+loop+with+sensor+and+Insulin&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-18T19:36:01.646Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02523131",
      "title": "Home Testing of Day and Night Closed Loop With Pump Suspend Feature",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus",
        "Diabetes Mellitus, Type 1",
        "Glucose Metabolism Disorders",
        "Endocrine System Diseases",
        "Autoimmune Diseases"
      ],
      "interventions": [
        {
          "name": "FlorenceM",
          "type": "DEVICE"
        },
        {
          "name": "Medtronic insulin pump 640G",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Cambridge",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 84,
      "start_date": "2016-05",
      "completion_date": "2018-03",
      "has_results": false,
      "last_update_posted_date": "2018-03-13",
      "last_synced_at": "2026-09-18T19:36:01.646Z",
      "location_count": 3,
      "location_summary": "Aurora, Colorado • Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02523131"
    },
    {
      "nct_id": "NCT05006040",
      "title": "HCL Single Arm Pilot Study in Treatment of Hyperglycemia of Pediatric ALL",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "High Risk Acute Lymphoblastic Leukemia"
      ],
      "interventions": [
        {
          "name": "Hybrid Closed Loop System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "26 Years",
        "sex": "ALL",
        "summary": "10 Years to 26 Years"
      },
      "enrollment_count": 1,
      "start_date": "2022-05-12",
      "completion_date": "2023-08-01",
      "has_results": false,
      "last_update_posted_date": "2024-05-03",
      "last_synced_at": "2026-09-18T19:36:01.646Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05006040"
    },
    {
      "nct_id": "NCT02925299",
      "title": "Day and Night Closed-loop in Young People With Type 1 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus",
        "Diabetes Mellitus, Type 1",
        "Glucose Metabolism Disorders",
        "Endocrine System Diseases",
        "Autoimmune Diseases"
      ],
      "interventions": [
        {
          "name": "FlorenceM (US) and FlorenceX (UK)",
          "type": "DEVICE"
        },
        {
          "name": "Insulin pump therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Years to 18 Years"
      },
      "enrollment_count": 131,
      "start_date": "2017-05-12",
      "completion_date": "2020-08-27",
      "has_results": false,
      "last_update_posted_date": "2021-02-02",
      "last_synced_at": "2026-09-18T19:36:01.646Z",
      "location_count": 5,
      "location_summary": "Palo Alto, California • Aurora, Colorado • Hartford, Connecticut + 2 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02925299"
    },
    {
      "nct_id": "NCT02463682",
      "title": "Early Feasibility Study of Zone-MPC and HMS With DiAs in the Outpatient Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 1"
      ],
      "interventions": [
        {
          "name": "CGM and Insulin Pump",
          "type": "DEVICE"
        },
        {
          "name": "Closed-Loop Control System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sansum Diabetes Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 9,
      "start_date": "2015-05",
      "completion_date": "2015-10",
      "has_results": false,
      "last_update_posted_date": "2016-04-11",
      "last_synced_at": "2026-09-18T19:36:01.646Z",
      "location_count": 3,
      "location_summary": "Santa Barbara, California • Rochester, Minnesota • Charlottesville, Virginia",
      "locations": [
        {
          "city": "Santa Barbara",
          "state": "California"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02463682"
    },
    {
      "nct_id": "NCT01552603",
      "title": "Artificial Pancreas Control System in an Inpatient Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Type I Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Artificial Pancreas Control Software",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Legacy Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 14,
      "start_date": "2012-03",
      "completion_date": "2013-09",
      "has_results": true,
      "last_update_posted_date": "2016-06-03",
      "last_synced_at": "2026-09-18T19:36:01.646Z",
      "location_count": 2,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01552603"
    },
    {
      "nct_id": "NCT04436796",
      "title": "The International Diabetes Closed Loop (iDCL) Trial: Protocol 4",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 1 Diabetes"
      ],
      "interventions": [
        {
          "name": "interoperable Artificial Pancreas System (iAPS)",
          "type": "DEVICE"
        },
        {
          "name": "Sensor-Augmented Pump (SAP)/Predictive Low Glucose Suspend (PLGS)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Sansum Diabetes Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2020-08-05",
      "completion_date": "2021-05-10",
      "has_results": true,
      "last_update_posted_date": "2022-12-02",
      "last_synced_at": "2026-09-18T19:36:01.646Z",
      "location_count": 5,
      "location_summary": "Santa Barbara, California • Stanford, California • Boston, Massachusetts + 2 more",
      "locations": [
        {
          "city": "Santa Barbara",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04436796"
    },
    {
      "nct_id": "NCT02135068",
      "title": "Preventing Hypoglycemia During Exercise With Proactive Snacking on Closed Loop",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Type 1 Diabetes"
      ],
      "interventions": [
        {
          "name": "Medtronic MiniMed Closed Loop (CL) System",
          "type": "DEVICE"
        },
        {
          "name": "Snacking",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "44 Years",
        "sex": "ALL",
        "summary": "13 Years to 44 Years"
      },
      "enrollment_count": 15,
      "start_date": "2015-01",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2020-04-20",
      "last_synced_at": "2026-09-18T19:36:01.646Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02135068"
    },
    {
      "nct_id": "NCT02679287",
      "title": "Project Nightlight: Efficacy and System Acceptance of Dinner/Night vs. 24hr Closed Loop Control",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 1"
      ],
      "interventions": [
        {
          "name": "CLC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 103,
      "start_date": "2016-02",
      "completion_date": "2019-04",
      "has_results": true,
      "last_update_posted_date": "2020-06-09",
      "last_synced_at": "2026-09-18T19:36:01.646Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02679287"
    },
    {
      "nct_id": "NCT02065895",
      "title": "Effect of Gain on Closed-Loop Insulin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 1 Diabetes"
      ],
      "interventions": [
        {
          "name": "HIGH error",
          "type": "DEVICE"
        },
        {
          "name": "NO error",
          "type": "DEVICE"
        },
        {
          "name": "LOW error",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Joslin Diabetes Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 8,
      "start_date": "2013-12",
      "completion_date": "2015-04",
      "has_results": true,
      "last_update_posted_date": "2018-05-17",
      "last_synced_at": "2026-09-18T19:36:01.646Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02065895"
    },
    {
      "nct_id": "NCT03844789",
      "title": "A Study of t:Slim X2 With Control-IQ Technology",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 1 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "t:slim X2 with Control-IQ Technology & Dexcom G6 CGM",
          "type": "DEVICE"
        },
        {
          "name": "Control Group",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "13 Years",
        "sex": "ALL",
        "summary": "6 Years to 13 Years"
      },
      "enrollment_count": 101,
      "start_date": "2019-06-06",
      "completion_date": "2020-03-20",
      "has_results": true,
      "last_update_posted_date": "2023-04-10",
      "last_synced_at": "2026-09-18T19:36:01.646Z",
      "location_count": 4,
      "location_summary": "Stanford, California • Aurora, Colorado • New Haven, Connecticut + 1 more",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03844789"
    }
  ]
}