{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cocaine+50+mg", "query": { "intervention": "Cocaine 50 mg" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 17, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cocaine+50+mg&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-25T13:10:38.240Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00631748", "title": "Quetiapine for the Reduction of Cocaine Use", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cocaine Dependence", "Cocaine Abuse", "Cocaine Addiction", "Drug Abuse", "Substance Abuse" ], "interventions": [ { "name": "quetiapine fumarate", "type": "DRUG" }, { "name": "Matched Placebo", "type": "DRUG" }, { "name": "Cognitive-behavioral Therapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Seattle Institute for Biomedical and Clinical Research", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 60, "start_date": "2008-02", "completion_date": "2010-07", "has_results": true, "last_update_posted_date": "2014-03-31", "last_synced_at": "2026-09-25T13:10:38.240Z", "location_count": 1, "location_summary": "Tacoma, Washington", "locations": [ { "city": "Tacoma", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00631748" }, { "nct_id": "NCT00654953", "title": "Clinical Efficacy of Sertraline Augmented With Gabapentin in Depressed, Recently Abstinent Cocaine-dependent Humans", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cocaine Dependence", "Depressive Symptoms" ], "interventions": [ { "name": "sertraline", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "gabapentin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Arkansas", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 102, "start_date": "2006-01", "completion_date": "2009-05", "has_results": true, "last_update_posted_date": "2011-04-25", "last_synced_at": "2026-09-25T13:10:38.240Z", "location_count": 1, "location_summary": "Little Rock, Arkansas", "locations": [ { "city": "Little Rock", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00654953" }, { "nct_id": "NCT00218049", "title": "Interaction Between Vanoxerine (GBR 12909) and Cocaine in Cocaine Dependent Individuals", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Cocaine Abuse", "Cocaine-Related Disorders" ], "interventions": [ { "name": "GBR 12909", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute on Drug Abuse (NIDA)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 3, "start_date": "2004-12", "completion_date": "2005-07", "has_results": false, "last_update_posted_date": "2017-01-12", "last_synced_at": "2026-09-25T13:10:38.240Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00218049" }, { "nct_id": "NCT00373880", "title": "Effects of Aripiprazole on Cocaine Craving and Self-Administration", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cocaine Abuse" ], "interventions": [ { "name": "Aripiprazole + Cocaine", "type": "DRUG" }, { "name": "Placebo + Cocaine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "New York State Psychiatric Institute", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "21 Years to 45 Years" }, "enrollment_count": 26, "start_date": "2005-04", "completion_date": "2008-09", "has_results": true, "last_update_posted_date": "2017-09-11", "last_synced_at": "2026-09-25T13:10:38.240Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00373880" }, { "nct_id": "NCT06025396", "title": "Multiple Ascending Dose Study of TMP-301 in Healthy Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Cocaine Use Disorder", "Substance Use Disorders", "Healthy Volunteers" ], "interventions": [ { "name": "Cohort 1 - TMP-301", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Cohort 2 - TMP-301", "type": "DRUG" }, { "name": "Cohort 3 - TMP-301", "type": "DRUG" }, { "name": "Cohort 4 - TMP-301", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Tempero Bio, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "59 Years", "sex": "ALL", "summary": "18 Years to 59 Years" }, "enrollment_count": 30, "start_date": "2023-01-06", "completion_date": "2024-01-02", "has_results": true, "last_update_posted_date": "2025-07-29", "last_synced_at": "2026-09-25T13:10:38.240Z", "location_count": 1, "location_summary": "Overland Park, Kansas", "locations": [ { "city": "Overland Park", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06025396" }, { "nct_id": "NCT06273540", "title": "Phase1, STP7 Cocaine Drug-Drug Interaction Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Cocaine Use Disorder" ], "interventions": [ { "name": "STP7 (mavoglurant)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Cocaine Hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Stalicla SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "59 Years", "sex": "ALL", "summary": "18 Years to 59 Years" }, "enrollment_count": 21, "start_date": "2024-04-15", "completion_date": "2024-10-07", "has_results": false, "last_update_posted_date": "2026-04-23", "last_synced_at": "2026-09-25T13:10:38.240Z", "location_count": 1, "location_summary": "Overland Park, Kansas", "locations": [ { "city": "Overland Park", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06273540" }, { "nct_id": "NCT00566969", "title": "Cocaine Withdrawal and Pharmacotherapy Response", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cocaine Dependence", "Opiate Dependence" ], "interventions": [ { "name": "sugar pill", "type": "DRUG" }, { "name": "Carvedilol 25 mg", "type": "DRUG" }, { "name": "Carvedilol 50 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 106, "start_date": "2007-09", "completion_date": "2013-01", "has_results": true, "last_update_posted_date": "2020-04-02", "last_synced_at": "2026-09-25T13:10:38.240Z", "location_count": 1, "location_summary": "West Haven, Connecticut", "locations": [ { "city": "West Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00566969" }, { "nct_id": "NCT00780442", "title": "D-Cycloserine and Cue Exposure in Cocaine-Dependent Individuals", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cocaine Use Disorders" ], "interventions": [ { "name": "D-cycloserine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 27, "start_date": "2006-09", "completion_date": "2008-07", "has_results": true, "last_update_posted_date": "2018-07-06", "last_synced_at": "2026-09-25T13:10:38.240Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00780442" }, { "nct_id": "NCT00759473", "title": "D-Cycloserine Facilitation of Cocaine - Cue Extinction", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cocaine Use Disorders" ], "interventions": [ { "name": "D-Cycloserine (DCS)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 79, "start_date": "2008-09", "completion_date": "2011-10", "has_results": true, "last_update_posted_date": "2016-04-13", "last_synced_at": "2026-09-25T13:10:38.240Z", "location_count": 2, "location_summary": "Charleston, South Carolina • Pickens, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" }, { "city": "Pickens", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00759473" }, { "nct_id": "NCT00218543", "title": "Atomoxetine for Treating Cocaine Abuse in Adults With Attention Deficit Hyperactivity Disorder (ADHD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Attention Deficit Disorder With Hyperactivity", "Cocaine-Related Disorders" ], "interventions": [ { "name": "Atomoxetine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "New York State Psychiatric Institute", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 20, "start_date": "2004-06", "completion_date": "2007-03", "has_results": true, "last_update_posted_date": "2019-04-24", "last_synced_at": "2026-09-25T13:10:38.240Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00218543" } ] }