{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cocoa+Extract",
    "query": {
      "intervention": "Cocoa Extract"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 69,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cocoa+Extract&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-09T02:06:18.101Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02062710",
      "title": "Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cough Reflex Sensitivity"
      ],
      "interventions": [
        {
          "name": "diphenhydramine/phenylephrine/cocoa; dextromethorophan; placebo",
          "type": "DRUG"
        },
        {
          "name": "diphenhydramine/phenylephrine/cocoa; placebo; dextromethorphan",
          "type": "DRUG"
        },
        {
          "name": "dextromethorphan; diphenhydramine/phenylephrine/cocoa; placebo",
          "type": "DRUG"
        },
        {
          "name": "dextromethorophan; placebo; diphenhydramine/phenylephrine/cocoa",
          "type": "DRUG"
        },
        {
          "name": "placebo; diphenhydramine/phenylephrine/cocoa; dextromethorphan",
          "type": "DRUG"
        },
        {
          "name": "placebo; dextromethorphan; diphenhydramine/phenylephrine/cocoa",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2014-01",
      "completion_date": "2014-06",
      "has_results": true,
      "last_update_posted_date": "2018-02-28",
      "last_synced_at": "2026-09-09T02:06:18.101Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02062710"
    },
    {
      "nct_id": "NCT04895800",
      "title": "An Evaluation of the Effects of a Non-Caffeinated Energy Dietary Supplement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Health Behavior"
      ],
      "interventions": [
        {
          "name": "Phytovive",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Caffeine",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Nova Southeastern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 36,
      "start_date": "2020-01-03",
      "completion_date": "2021-03-15",
      "has_results": false,
      "last_update_posted_date": "2021-06-09",
      "last_synced_at": "2026-09-09T02:06:18.101Z",
      "location_count": 1,
      "location_summary": "Davie, Florida",
      "locations": [
        {
          "city": "Davie",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04895800"
    },
    {
      "nct_id": "NCT04582617",
      "title": "Investigating the Effects of Cocoa Flavanol on Cognition Assessed Online",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Cognitive Change"
      ],
      "interventions": [
        {
          "name": "Cocoa Extract",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Cocoa Extract Placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Multivitamin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Multivitamin placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 3959,
      "start_date": "2016-08-26",
      "completion_date": "2020-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-04-07",
      "last_synced_at": "2026-09-09T02:06:18.101Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • New York, New York",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04582617"
    },
    {
      "nct_id": "NCT02408289",
      "title": "The Randomized Controlled Cocoa-Appetite Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Lo-Flav",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Hi-Flav",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Epicatechin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Procyanidins",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Brooklyn College of the City University of New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "MALE",
        "summary": "18 Years to 35 Years · Male only"
      },
      "enrollment_count": 28,
      "start_date": "2015-03",
      "completion_date": "2015-05",
      "has_results": false,
      "last_update_posted_date": "2016-01-13",
      "last_synced_at": "2026-09-09T02:06:18.101Z",
      "location_count": 1,
      "location_summary": "Brooklyn, New York",
      "locations": [
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02408289"
    },
    {
      "nct_id": "NCT01312233",
      "title": "Collaborative Care for Older Adults With Back Pain (COCOA)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Medical Care",
          "type": "OTHER"
        },
        {
          "name": "Dual Care",
          "type": "OTHER"
        },
        {
          "name": "Shared Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Palmer College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 131,
      "start_date": "2011-03",
      "completion_date": "2013-03",
      "has_results": true,
      "last_update_posted_date": "2021-03-30",
      "last_synced_at": "2026-09-09T02:06:18.101Z",
      "location_count": 2,
      "location_summary": "Davenport, Iowa",
      "locations": [
        {
          "city": "Davenport",
          "state": "Iowa"
        },
        {
          "city": "Davenport",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01312233"
    },
    {
      "nct_id": "NCT07161726",
      "title": "Cocoa to Maximize Exercise Training in Older Adults - The COMET Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Mobility Disability"
      ],
      "interventions": [
        {
          "name": "(-)-Epicatechin-rich cocoa supplementation combined with exercise training",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Placebo combined with exercise training",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2026-04-21",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-08",
      "last_synced_at": "2026-09-09T02:06:18.101Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07161726"
    },
    {
      "nct_id": "NCT03035201",
      "title": "COcoa Supplement and Multivitamin Outcomes Study for the Mind",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cognitive Impairment",
        "Dementia",
        "Aging"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 2262,
      "start_date": "2016-09",
      "completion_date": "2021-02-12",
      "has_results": true,
      "last_update_posted_date": "2023-08-22",
      "last_synced_at": "2026-09-09T02:06:18.101Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03035201"
    },
    {
      "nct_id": "NCT01886989",
      "title": "Cocoa Polyphenols and Postprandial Metabolism in Type 2 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "Cocoa polyphenols",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Arpita Basu",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 18,
      "start_date": "2012-01",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2018-01-23",
      "last_synced_at": "2026-09-09T02:06:18.101Z",
      "location_count": 1,
      "location_summary": "Stillwater, Oklahoma",
      "locations": [
        {
          "city": "Stillwater",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01886989"
    },
    {
      "nct_id": "NCT03214133",
      "title": "Effects of Epicatechin-rich Cocoa on Collagen Synthesis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Collagen Synthesis"
      ],
      "interventions": [
        {
          "name": "Epicatechin-rich cocoa dose response",
          "type": "OTHER"
        },
        {
          "name": "Epicatechin-rich cocoa vs placebo on performance",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "25 Years",
        "sex": "MALE",
        "summary": "18 Years to 25 Years · Male only"
      },
      "enrollment_count": 12,
      "start_date": "2017-05-23",
      "completion_date": "2018-08-30",
      "has_results": false,
      "last_update_posted_date": "2021-08-03",
      "last_synced_at": "2026-09-09T02:06:18.101Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03214133"
    },
    {
      "nct_id": "NCT02530385",
      "title": "Fecal Microbiota Transplant for Improvement of Metabolism",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Placebo Capsules",
          "type": "OTHER"
        },
        {
          "name": "FMT Capsules",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BIOLOGICAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "25 Years to 60 Years"
      },
      "enrollment_count": 24,
      "start_date": "2016-06",
      "completion_date": "2018-06-27",
      "has_results": true,
      "last_update_posted_date": "2019-07-25",
      "last_synced_at": "2026-09-09T02:06:18.101Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02530385"
    }
  ]
}