{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cocoa+polyphenols",
    "query": {
      "intervention": "Cocoa polyphenols"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 14,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cocoa+polyphenols&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-12T22:04:01.613Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01483508",
      "title": "Absorption and Metabolism of Dietary Cocoa Procyanidins in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Flavanol- and procyanidins-containing drink",
          "type": "OTHER"
        },
        {
          "name": "Procyanidins-containing drink",
          "type": "OTHER"
        },
        {
          "name": "Flavanol-containing drink",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 12,
      "start_date": "2008-02",
      "completion_date": "2008-08",
      "has_results": false,
      "last_update_posted_date": "2012-10-25",
      "last_synced_at": "2026-09-12T22:04:01.613Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01483508"
    },
    {
      "nct_id": "NCT03194620",
      "title": "Absorption, Metabolism and Excretion of Dietary Polyphenolic Bioactives in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Thearubigins",
          "type": "OTHER"
        },
        {
          "name": "Theaflavins",
          "type": "OTHER"
        },
        {
          "name": "Procyanidin Dimer B2 (DB2)",
          "type": "OTHER"
        },
        {
          "name": "(-)-Epigallocatechin-3-O-gallate (EGCG)",
          "type": "OTHER"
        },
        {
          "name": "(-)-Epicatechin-3-O-gallate (ECG)",
          "type": "OTHER"
        },
        {
          "name": "(-)-Epicatechin (EC)",
          "type": "OTHER"
        },
        {
          "name": "(-)-Epigallocatechin (EGC)",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "60 Years",
        "sex": "MALE",
        "summary": "25 Years to 60 Years · Male only"
      },
      "enrollment_count": 12,
      "start_date": "2016-08",
      "completion_date": "2017-01-12",
      "has_results": false,
      "last_update_posted_date": "2017-11-06",
      "last_synced_at": "2026-09-12T22:04:01.613Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03194620"
    },
    {
      "nct_id": "NCT03201822",
      "title": "Intake-dependent Effect of Cocoa Flavanol Absorption, Metabolism and Excretion in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "100 mg of Cocoa Flavanols/70 kg BW",
          "type": "OTHER"
        },
        {
          "name": "200 mg of Cocoa Flavanols/70 kg BW",
          "type": "OTHER"
        },
        {
          "name": "400 mg of Cocoa Flavanols/70 kg BW",
          "type": "OTHER"
        },
        {
          "name": "1000 mg of Cocoa Flavanols/70 kg BW",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "40 Years",
        "sex": "MALE",
        "summary": "25 Years to 40 Years · Male only"
      },
      "enrollment_count": 14,
      "start_date": "2013-04-01",
      "completion_date": "2013-05-25",
      "has_results": false,
      "last_update_posted_date": "2017-06-28",
      "last_synced_at": "2026-09-12T22:04:01.613Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03201822"
    },
    {
      "nct_id": "NCT03501238",
      "title": "Interaction of Salivary Proteins and Polyphenols",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diet Habit",
        "Diet Modification",
        "Taste, Altered",
        "Saliva Altered"
      ],
      "interventions": [
        {
          "name": "Chocolate Milk",
          "type": "OTHER"
        },
        {
          "name": "Chocolate milk substitute",
          "type": "OTHER"
        },
        {
          "name": "Chocolate milk substitute with gelatin",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 63,
      "start_date": "2017-06-08",
      "completion_date": "2018-01-01",
      "has_results": false,
      "last_update_posted_date": "2023-05-25",
      "last_synced_at": "2026-09-12T22:04:01.613Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03501238"
    },
    {
      "nct_id": "NCT01886989",
      "title": "Cocoa Polyphenols and Postprandial Metabolism in Type 2 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "Cocoa polyphenols",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Arpita Basu",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 18,
      "start_date": "2012-01",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2018-01-23",
      "last_synced_at": "2026-09-12T22:04:01.613Z",
      "location_count": 1,
      "location_summary": "Stillwater, Oklahoma",
      "locations": [
        {
          "city": "Stillwater",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01886989"
    },
    {
      "nct_id": "NCT03419052",
      "title": "MINDSpeed Food and Brain Training RCT",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Education",
        "Cognition",
        "Cognitive Training",
        "Polyphenols"
      ],
      "interventions": [
        {
          "name": "Speed of processing training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "MIND foods",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive training control",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control foods",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 212,
      "start_date": "2019-01-10",
      "completion_date": "2024-03-08",
      "has_results": true,
      "last_update_posted_date": "2025-03-07",
      "last_synced_at": "2026-09-12T22:04:01.613Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03419052"
    },
    {
      "nct_id": "NCT03526094",
      "title": "Flavanol Absorption, Metabolism and Excretion From Fruit-based Drinks and Other Food Matrixes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Flavanols-capsules",
          "type": "OTHER"
        },
        {
          "name": "Flavanol-banana blend",
          "type": "OTHER"
        },
        {
          "name": "Flavanol-high protein drink",
          "type": "OTHER"
        },
        {
          "name": "Flavanol-berry blend",
          "type": "OTHER"
        },
        {
          "name": "Flavanol-sports drink",
          "type": "OTHER"
        },
        {
          "name": "Flavanol-peanut butter toast",
          "type": "OTHER"
        },
        {
          "name": "Flavanol-oats",
          "type": "OTHER"
        },
        {
          "name": "Flavanol-yogurt",
          "type": "OTHER"
        },
        {
          "name": "II- Flavanol drink",
          "type": "OTHER"
        },
        {
          "name": "II- Flavanol drink + banana blend",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "60 Years",
        "sex": "MALE",
        "summary": "25 Years to 60 Years · Male only"
      },
      "enrollment_count": 23,
      "start_date": "2016-05-05",
      "completion_date": "2018-02-09",
      "has_results": false,
      "last_update_posted_date": "2022-10-10",
      "last_synced_at": "2026-09-12T22:04:01.613Z",
      "location_count": 2,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        },
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03526094"
    },
    {
      "nct_id": "NCT01969994",
      "title": "Absorption, Metabolism, and Excretion of (-)-[2-14C]Epicatechin in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ADME"
      ],
      "interventions": [
        {
          "name": "Controlled dietary background",
          "type": "OTHER"
        },
        {
          "name": "(-)-[2-14C]epicatechin intake",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Institutes for Pharmaceutical Discovery, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "MALE",
        "summary": "18 Years to 50 Years · Male only"
      },
      "enrollment_count": 12,
      "start_date": "2009-12",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2013-10-25",
      "last_synced_at": "2026-09-12T22:04:01.613Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01969994"
    },
    {
      "nct_id": "NCT02203240",
      "title": "Cocoa and Metabolic Health in Prediabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prediabetes"
      ],
      "interventions": [
        {
          "name": "Cocoa",
          "type": "OTHER"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "40 Years to 75 Years"
      },
      "enrollment_count": 16,
      "start_date": "2014-06",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2023-09-21",
      "last_synced_at": "2026-09-12T22:04:01.613Z",
      "location_count": 1,
      "location_summary": "Blacksburg, Virginia",
      "locations": [
        {
          "city": "Blacksburg",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02203240"
    },
    {
      "nct_id": "NCT00639665",
      "title": "Cocoa, Polyphenols, and the Kidney in Healthy Subjects and in Subjects With Hypertension and Diabetes Mellitus",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "Cocoa",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 228,
      "start_date": "2008-01",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2015-03-31",
      "last_synced_at": "2026-09-12T22:04:01.613Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00639665"
    }
  ]
}