{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cognitive+Behavioral+Therapy+for+insomnia+and+depression&page=2",
    "query": {
      "intervention": "Cognitive Behavioral Therapy for insomnia and depression",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 43,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cognitive+Behavioral+Therapy+for+insomnia+and+depression&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cognitive+Behavioral+Therapy+for+insomnia+and+depression&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T21:00:55.430Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07071350",
      "title": "Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Autonomic Nervous System Disease",
        "Concussive Injury",
        "Mild Traumatic Brain Injury",
        "Post Traumatic Stress Disorder",
        "Persistent Post Concussion Syndrome"
      ],
      "interventions": [
        {
          "name": "HRV Coherence Ratio",
          "type": "OTHER"
        },
        {
          "name": "NSI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pittsburgh Sleep Quality Index (PSQI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Quantitative Sleep Measures",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Global Impression of Change (PGIC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Performance/NIH Toolbox Cognitive Battery",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pain Interference/TBI-QoL Pain Interference Short-Form",
          "type": "OTHER"
        },
        {
          "name": "Patient Health Questionnaire-9 (PHQ-9)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PTSD Checklist for DSM-5 (PCL-5)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "HRV Biofeedback (HRV-B)",
          "type": "OTHER"
        },
        {
          "name": "Psychoeducational (Edu) Comparator Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 148,
      "start_date": "2025-09-02",
      "completion_date": "2028-09",
      "has_results": false,
      "last_update_posted_date": "2026-09-22",
      "last_synced_at": "2026-10-06T21:00:55.430Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07071350"
    },
    {
      "nct_id": "NCT02741336",
      "title": "Electrophysiologic Changes in Blacks Treated With CBT for Insomnia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insomnia"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Insomnia (CBT-I)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Self-Monitoring",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "State University of New York - Downstate Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 50 Years · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2015-11",
      "completion_date": "2017-06",
      "has_results": false,
      "last_update_posted_date": "2017-09-13",
      "last_synced_at": "2026-10-06T21:00:55.430Z",
      "location_count": 1,
      "location_summary": "Brooklyn, New York",
      "locations": [
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02741336"
    },
    {
      "nct_id": "NCT00767624",
      "title": "TRIAD - Treatment of Insomnia and Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Sleep Initiation and Maintenance Disorders",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Antidepressant",
          "type": "DRUG"
        },
        {
          "name": "Desensitization Therapy for Insomnia",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Behavioral Therapy for Insomnia",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 150,
      "start_date": "2008-12",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2016-12-05",
      "last_synced_at": "2026-10-06T21:00:55.430Z",
      "location_count": 3,
      "location_summary": "Stanford, California • Durham, North Carolina • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00767624"
    },
    {
      "nct_id": "NCT06373718",
      "title": "Sleep Mechanisms Of Regulating Emotions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insomnia",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Insomnia",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 120,
      "start_date": "2024-08-12",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-10-06T21:00:55.430Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06373718"
    },
    {
      "nct_id": "NCT01743339",
      "title": "Managing Sleep Symptoms and Modifying Mechanisms of Traumatic Stress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress Disorders, Post-Traumatic",
        "Depression",
        "Sleep"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 110,
      "start_date": "2013-01",
      "completion_date": "2017-02",
      "has_results": false,
      "last_update_posted_date": "2017-04-27",
      "last_synced_at": "2026-10-06T21:00:55.430Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01743339"
    },
    {
      "nct_id": "NCT03322774",
      "title": "Sleep To Reduce Incident Depression Effectively",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insomnia, Primary",
        "Major Depressive Disorder",
        "Rumination"
      ],
      "interventions": [
        {
          "name": "digital Cognitive Behavioral Therapy for Insomnia",
          "type": "BEHAVIORAL"
        },
        {
          "name": "face-to-face Cognitive Behavioral Therapy for Insomnia",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sleep Hygiene Education Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1237,
      "start_date": "2018-03-09",
      "completion_date": "2024-06-27",
      "has_results": false,
      "last_update_posted_date": "2024-10-01",
      "last_synced_at": "2026-10-06T21:00:55.430Z",
      "location_count": 1,
      "location_summary": "Novi, Michigan",
      "locations": [
        {
          "city": "Novi",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03322774"
    },
    {
      "nct_id": "NCT03596879",
      "title": "Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insomnia",
        "Post Partum Depression"
      ],
      "interventions": [
        {
          "name": "dCBTI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sleep Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 91,
      "start_date": "2018-07-18",
      "completion_date": "2019-07-31",
      "has_results": false,
      "last_update_posted_date": "2019-12-05",
      "last_synced_at": "2026-10-06T21:00:55.430Z",
      "location_count": 1,
      "location_summary": "Novi, Michigan",
      "locations": [
        {
          "city": "Novi",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03596879"
    },
    {
      "nct_id": "NCT03603717",
      "title": "RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insomnia",
        "Suicidal Ideation"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Insomnia",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sleep Hygiene",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 283,
      "start_date": "2019-02-18",
      "completion_date": "2023-06-30",
      "has_results": true,
      "last_update_posted_date": "2024-06-17",
      "last_synced_at": "2026-10-06T21:00:55.430Z",
      "location_count": 3,
      "location_summary": "Buffalo, New York • Canandaigua, New York • Syracuse, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Canandaigua",
          "state": "New York"
        },
        {
          "city": "Syracuse",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03603717"
    },
    {
      "nct_id": "NCT05523726",
      "title": "Preventing Insomnia With Virtual Oneshot Therapy (PIVOT)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insomnia"
      ],
      "interventions": [
        {
          "name": "pCBT-I",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 167,
      "start_date": "2022-12-01",
      "completion_date": "2026-03-13",
      "has_results": false,
      "last_update_posted_date": "2026-03-17",
      "last_synced_at": "2026-10-06T21:00:55.430Z",
      "location_count": 1,
      "location_summary": "Novi, Michigan",
      "locations": [
        {
          "city": "Novi",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05523726"
    },
    {
      "nct_id": "NCT02660385",
      "title": "Insomnia Self-Management in Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Failure",
        "Heart Failure",
        "Congestive Heart Failure",
        "Heart Failure, Congestive",
        "Sleep Initiation and Maintenance Disorders",
        "Chronic Insomnia",
        "Disorders of Initiating and Maintaining Sleep",
        "Fatigue",
        "Pain",
        "Depressive Symptoms",
        "Sleep Disorders",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Insomnia",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Self-Management Education for Heart Failure",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 195,
      "start_date": "2016-03-07",
      "completion_date": "2021-11-30",
      "has_results": true,
      "last_update_posted_date": "2023-02-09",
      "last_synced_at": "2026-10-06T21:00:55.430Z",
      "location_count": 1,
      "location_summary": "West Haven, Connecticut",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02660385"
    }
  ]
}