{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Coherence", "query": { "intervention": "Coherence" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 404, "total_pages": 41, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Coherence&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-02T03:17:00.547Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01773954", "title": "Repeated Eye Injections of Aflibercept for Treatment of Wet Age Related Macular Degeneration", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Age-Related Macular Degeneration", "Macular Degeneration" ], "interventions": [ { "name": "Intravitreal Aflibercept Injection", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "MidAtlantic Retina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2013-02", "completion_date": "2016-03", "has_results": true, "last_update_posted_date": "2018-05-02", "last_synced_at": "2026-09-02T03:17:00.547Z", "location_count": 3, "location_summary": "Cherry Hill, New Jersey • Huntingdon Valley, Pennsylvania • Philadelphia, Pennsylvania", "locations": [ { "city": "Cherry Hill", "state": "New Jersey" }, { "city": "Huntingdon Valley", "state": "Pennsylvania" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01773954" }, { "nct_id": "NCT03323307", "title": "Low Cost OCT for Point of Care", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Optical Coherence Tomography (OCT) of the Retina" ], "interventions": [ { "name": "OCT imaging", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 70, "start_date": "2018-03-28", "completion_date": "2018-12-13", "has_results": true, "last_update_posted_date": "2019-12-05", "last_synced_at": "2026-09-02T03:17:00.547Z", "location_count": 1, "location_summary": "Chapel Hill, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03323307" }, { "nct_id": "NCT01826175", "title": "Comparison of Ticagrelor Versus Clopidogrel on Residual Thrombus Burden During PCI: an OCT Study", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Acute Coronary Syndrome", "Coronary Artery Disease" ], "interventions": [ { "name": "Ticagrelor", "type": "DRUG" }, { "name": "Clopidogrel", "type": "DRUG" }, { "name": "Optical Coherence Tomography", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "18 Years to 79 Years" }, "enrollment_count": 0, "start_date": "2013-05", "completion_date": "2014-05", "has_results": false, "last_update_posted_date": "2016-12-20", "last_synced_at": "2026-09-02T03:17:00.547Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01826175" }, { "nct_id": "NCT05145322", "title": "In Vivo Assessment of the Tooth-Resin Composite Interface Using Optical Coherence Tomography", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cavity", "Cavities of Teeth" ], "interventions": [ { "name": "Composite with 90 degree cavosurface angle", "type": "DEVICE" }, { "name": "Composite with wide bevel", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 36, "start_date": "2021-09-23", "completion_date": "2024-10-16", "has_results": true, "last_update_posted_date": "2024-10-28", "last_synced_at": "2026-09-02T03:17:00.547Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT05145322" }, { "nct_id": "NCT03507036", "title": "Radio Frequency Microneedling for Suprapatellar Skin", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Skin Laxity" ], "interventions": [ { "name": "Profound system", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 20, "start_date": "2018-03-15", "completion_date": "2019-05-01", "has_results": true, "last_update_posted_date": "2020-12-03", "last_synced_at": "2026-09-02T03:17:00.547Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03507036" }, { "nct_id": "NCT07071350", "title": "Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Autonomic Nervous System Disease", "Concussive Injury", "Mild Traumatic Brain Injury", "Post Traumatic Stress Disorder", "Persistent Post Concussion Syndrome" ], "interventions": [ { "name": "HRV Coherence Ratio", "type": "OTHER" }, { "name": "NSI", "type": "BEHAVIORAL" }, { "name": "Pittsburgh Sleep Quality Index (PSQI)", "type": "BEHAVIORAL" }, { "name": "Quantitative Sleep Measures", "type": "BEHAVIORAL" }, { "name": "Patient Global Impression of Change (PGIC)", "type": "BEHAVIORAL" }, { "name": "Cognitive Performance/NIH Toolbox Cognitive Battery", "type": "BEHAVIORAL" }, { "name": "Pain Interference/TBI-QoL Pain Interference Short-Form", "type": "OTHER" }, { "name": "Patient Health Questionnaire-9 (PHQ-9)", "type": "BEHAVIORAL" }, { "name": "PTSD Checklist for DSM-5 (PCL-5)", "type": "BEHAVIORAL" }, { "name": "HRV Biofeedback (HRV-B)", "type": "OTHER" }, { "name": "Psychoeducational (Edu) Comparator Intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER", "BEHAVIORAL" ], "sponsor": "Virginia Commonwealth University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 148, "start_date": "2025-09-02", "completion_date": "2028-09", "has_results": false, "last_update_posted_date": "2025-09-17", "last_synced_at": "2026-09-02T03:17:00.547Z", "location_count": 1, "location_summary": "Richmond, Virginia", "locations": [ { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT07071350" }, { "nct_id": "NCT05294978", "title": "EyeConic: Qualification for Cone-Optogenetics", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Retinal Dystrophies" ], "interventions": [ { "name": "Optical coherence tomography (OCT)", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Institute of Molecular and Clinical Ophthalmology Basel", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1000, "start_date": "2021-07-01", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2025-07-31", "last_synced_at": "2026-09-02T03:17:00.547Z", "location_count": 3, "location_summary": "San Francisco, California • Miami, Florida • Pittsburgh, Pennsylvania", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05294978" }, { "nct_id": "NCT01934556", "title": "A Safety and Efficacy Trial of a Treat and Extend Protocol Using Ranibizumab With and Without Laser Photocoagulation for Diabetic Macular Edema", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Diabetic Macular Edema" ], "interventions": [ { "name": "Ranibizumab 0.3 mg intravitreal injection", "type": "DRUG" }, { "name": "Guided Laser Photocoagulation", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Palmetto Retina Center, LLC", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 150, "start_date": "2013-11", "completion_date": "2018-04", "has_results": true, "last_update_posted_date": "2020-11-17", "last_synced_at": "2026-09-02T03:17:00.547Z", "location_count": 3, "location_summary": "Beverly Hills, California • West Columbia, South Carolina • Houston, Texas", "locations": [ { "city": "Beverly Hills", "state": "California" }, { "city": "West Columbia", "state": "South Carolina" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01934556" }, { "nct_id": "NCT04573660", "title": "Abbott Vascular Medical Device Registry", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Acute Myocardial Infarction", "Restenoses, Coronary", "Coronary Artery Lesions", "Venous Embolism", "Arterial Embolism" ], "interventions": [ { "name": "Coronary and peripheral stents", "type": "DEVICE" }, { "name": "Pacing catheters", "type": "DEVICE" }, { "name": "Vascular plugs", "type": "DEVICE" }, { "name": "Measurement and imaging (FFR and OCT)", "type": "DEVICE" }, { "name": "Peripheral dilatation catheters", "type": "DEVICE" }, { "name": "Coronary dilatation catheters", "type": "DEVICE" }, { "name": "Coronary and peripheral guidewires", "type": "DEVICE" }, { "name": "Vessel closure/compression devices", "type": "DEVICE" }, { "name": "Vascular access introducers", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Abbott Medical Devices", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3784, "start_date": "2020-10-25", "completion_date": "2031-11", "has_results": false, "last_update_posted_date": "2025-07-03", "last_synced_at": "2026-09-02T03:17:00.547Z", "location_count": 7, "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 4 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Los Angeles", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Lincoln", "state": "Nebraska" } ], "official_url": "https://clinicaltrials.gov/study/NCT04573660" }, { "nct_id": "NCT04356027", "title": "FUnctional diagnoSIs of corONary Stenosis (FUSION)", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Coronary Artery Disease", "Coronary Stenosis" ], "interventions": [ { "name": "ICA (Invasive Coronary Angiography)", "type": "PROCEDURE" }, { "name": "OCT", "type": "PROCEDURE" }, { "name": "FFR", "type": "PROCEDURE" }, { "name": "VFR Analysis", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "OTHER" ], "sponsor": "Abbott Medical Devices", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 312, "start_date": "2020-06-26", "completion_date": "2021-10-15", "has_results": true, "last_update_posted_date": "2025-02-21", "last_synced_at": "2026-09-02T03:17:00.547Z", "location_count": 28, "location_summary": "Huntsville, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 22 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Palo Alto", "state": "California" }, { "city": "Santa Monica", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04356027" } ] }