{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Coherence+Breathing",
    "query": {
      "intervention": "Coherence Breathing"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T00:38:23.580Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05627687",
      "title": "Caring Relationships Expression Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Caregiver Burden",
        "Anxiety",
        "Stress"
      ],
      "interventions": [
        {
          "name": "Heart Rate Variability Biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Music Listening Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2021-12-13",
      "completion_date": "2023-07-01",
      "has_results": false,
      "last_update_posted_date": "2024-02-12",
      "last_synced_at": "2026-09-03T00:38:23.580Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05627687"
    },
    {
      "nct_id": "NCT07071350",
      "title": "Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Autonomic Nervous System Disease",
        "Concussive Injury",
        "Mild Traumatic Brain Injury",
        "Post Traumatic Stress Disorder",
        "Persistent Post Concussion Syndrome"
      ],
      "interventions": [
        {
          "name": "HRV Coherence Ratio",
          "type": "OTHER"
        },
        {
          "name": "NSI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pittsburgh Sleep Quality Index (PSQI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Quantitative Sleep Measures",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Global Impression of Change (PGIC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Performance/NIH Toolbox Cognitive Battery",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pain Interference/TBI-QoL Pain Interference Short-Form",
          "type": "OTHER"
        },
        {
          "name": "Patient Health Questionnaire-9 (PHQ-9)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PTSD Checklist for DSM-5 (PCL-5)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "HRV Biofeedback (HRV-B)",
          "type": "OTHER"
        },
        {
          "name": "Psychoeducational (Edu) Comparator Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 148,
      "start_date": "2025-09-02",
      "completion_date": "2028-09",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-09-03T00:38:23.580Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07071350"
    },
    {
      "nct_id": "NCT07297901",
      "title": "App-based Breathing Program for Migraine Relief",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine",
        "Heart Rate Variability (HRV)",
        "Autonomic Nervous System",
        "Headache (Migraine)",
        "Headache",
        "Chronic Pain",
        "mHealth",
        "Breathing"
      ],
      "interventions": [
        {
          "name": "Baseline Survey",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Heart rate variability biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham Control Group",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2025-12-15",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-23",
      "last_synced_at": "2026-09-03T00:38:23.580Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07297901"
    },
    {
      "nct_id": "NCT05687240",
      "title": "Heart Focused Movement Effects on Cardiometabolic Risk",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiometabolic Risk Factors"
      ],
      "interventions": [
        {
          "name": "Qigong/Tai Chi",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Heart rate variability biofeedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "55 Years to 85 Years"
      },
      "enrollment_count": 22,
      "start_date": "2020-12-01",
      "completion_date": "2023-07-31",
      "has_results": false,
      "last_update_posted_date": "2024-02-12",
      "last_synced_at": "2026-09-03T00:38:23.580Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05687240"
    },
    {
      "nct_id": "NCT03816540",
      "title": "Diaphragmatic Breathing and Heart Rate Variability Training for Improving Hypertension in Fragile X Associated Tremor/Ataxia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Hypertension",
        "FXTAS"
      ],
      "interventions": [
        {
          "name": "HRV and respiratory coherence biofeedback",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "50 Years to 90 Years"
      },
      "enrollment_count": 20,
      "start_date": "2018-05-01",
      "completion_date": "2019-03-13",
      "has_results": false,
      "last_update_posted_date": "2019-10-22",
      "last_synced_at": "2026-09-03T00:38:23.580Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03816540"
    },
    {
      "nct_id": "NCT01599598",
      "title": "Coherence Training for Military Personnel",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress"
      ],
      "interventions": [
        {
          "name": "Progressive Muscle Relaxation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Coherence Advantage",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "United States Naval Medical Center, San Diego",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 192,
      "start_date": "2012-04",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2016-08-19",
      "last_synced_at": "2026-09-03T00:38:23.580Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01599598"
    },
    {
      "nct_id": "NCT03198780",
      "title": "Mindful Breathing Awareness Through Pursed-Lip Breathing Training",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease"
      ],
      "interventions": [
        {
          "name": "Breathing Awareness",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Minnesota HealthSolutions",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2018-10-01",
      "completion_date": "2019-07-31",
      "has_results": false,
      "last_update_posted_date": "2019-10-29",
      "last_synced_at": "2026-09-03T00:38:23.580Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03198780"
    },
    {
      "nct_id": "NCT05370287",
      "title": "Adaptive Optics Retinal Imaging",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Glaucoma, Primary Open Angle"
      ],
      "interventions": [
        {
          "name": "oxygen inhalation",
          "type": "OTHER"
        },
        {
          "name": "Adaptive optics imaging",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Food and Drug Administration (FDA)",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2018-01-22",
      "completion_date": "2028-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-08",
      "last_synced_at": "2026-09-03T00:38:23.580Z",
      "location_count": 1,
      "location_summary": "Silver Spring, Maryland",
      "locations": [
        {
          "city": "Silver Spring",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05370287"
    },
    {
      "nct_id": "NCT03259438",
      "title": "The Vitality Project for Fatigued Female Cancer Survivors",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fatigue",
        "Cancer Survivorship"
      ],
      "interventions": [
        {
          "name": "Qigong",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Healthy Living (CHIP + Pre-Train)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The Miriam Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 70 Years · Female only"
      },
      "enrollment_count": 75,
      "start_date": "2017-07-24",
      "completion_date": "2018-01-30",
      "has_results": false,
      "last_update_posted_date": "2017-08-23",
      "last_synced_at": "2026-09-03T00:38:23.580Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03259438"
    },
    {
      "nct_id": "NCT07650279",
      "title": "Coherence Breathing Before Cardiopulmonary Exercise Testing",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breathing Rate"
      ],
      "interventions": [
        {
          "name": "Coherence Breathing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Spontaneous Breathing",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Human Performance Lab of Monmouth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "19 Years to 45 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-06-11",
      "completion_date": "2026-10-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-18",
      "last_synced_at": "2026-09-03T00:38:23.580Z",
      "location_count": 1,
      "location_summary": "West Long Branch, New Jersey",
      "locations": [
        {
          "city": "West Long Branch",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07650279"
    }
  ]
}