{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cold+Pressor+Test&page=2",
    "query": {
      "intervention": "Cold Pressor Test",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cold+Pressor+Test&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-21T07:10:00.792Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07160049",
      "title": "Wearable Focused Ultrasound Stimulation for Peripheral Nerve Pain Management",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain Management",
        "Peripheral Neuropathic Pain"
      ],
      "interventions": [
        {
          "name": "Cold Pressor Task - Upper Limb",
          "type": "DEVICE"
        },
        {
          "name": "Algometry Pain Tests in the Upper Limb",
          "type": "DEVICE"
        },
        {
          "name": "Algometry Pain Tests in the Lower Limb",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Evan (Huiliang) Wang",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "20 Years to 40 Years"
      },
      "enrollment_count": 8,
      "start_date": "2025-07-14",
      "completion_date": "2025-10-15",
      "has_results": false,
      "last_update_posted_date": "2026-06-10",
      "last_synced_at": "2026-09-21T07:10:00.792Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07160049"
    },
    {
      "nct_id": "NCT00678717",
      "title": "Microneurography and Spinal Cord Stimulation in Chronic Visceral Pain",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Autonomic Evaluation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 36,
      "start_date": "2008-02",
      "completion_date": "2009-01-23",
      "has_results": false,
      "last_update_posted_date": "2018-03-16",
      "last_synced_at": "2026-09-21T07:10:00.792Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00678717"
    },
    {
      "nct_id": "NCT04858178",
      "title": "Transcutaneous Spinal Cord Neuromodulation to Normalize Autonomic Phenotypes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Autonomic Imbalance",
        "Autonomic Dysreflexia",
        "Orthostatic; Hypotension, Neurogenic"
      ],
      "interventions": [
        {
          "name": "Tests of sympathetic inhibition",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Tests of sympathetic activation",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Testing of autonomic dysreflexia",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Transcutaneous spinal cord stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "DEVICE"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 4,
      "start_date": "2022-02-17",
      "completion_date": "2022-11-14",
      "has_results": false,
      "last_update_posted_date": "2023-04-14",
      "last_synced_at": "2026-09-21T07:10:00.792Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04858178"
    },
    {
      "nct_id": "NCT03786952",
      "title": "Stress, Sex, and the Generalization of Fear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Psychological Stress"
      ],
      "interventions": [
        {
          "name": "Stress immediately before learning in males",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham control immediately before learning in males",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stress 30 minutes before learning in males",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham control 30 minutes before learning in males",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stress immediately before learning in females",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham control immediately before learning in females",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stress 30 minutes before learning in females",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham control 30 minutes before learning in females",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio Northern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 606,
      "start_date": "2019-01-25",
      "completion_date": "2022-06-30",
      "has_results": true,
      "last_update_posted_date": "2023-03-23",
      "last_synced_at": "2026-09-21T07:10:00.792Z",
      "location_count": 1,
      "location_summary": "Ada, Ohio",
      "locations": [
        {
          "city": "Ada",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03786952"
    },
    {
      "nct_id": "NCT00838695",
      "title": "Variability in Adrenergic Response",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vascular Reaction to Medications"
      ],
      "interventions": [
        {
          "name": "Phenylephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 106,
      "start_date": "2009-01",
      "completion_date": "2011-12",
      "has_results": true,
      "last_update_posted_date": "2018-10-26",
      "last_synced_at": "2026-09-21T07:10:00.792Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00838695"
    },
    {
      "nct_id": "NCT05619419",
      "title": "Study of Affect Induction for Lab Induced Pain in Healthy Undergraduates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Meditation",
        "Pain",
        "Mindfulness",
        "Affect",
        "Emotion Regulation"
      ],
      "interventions": [
        {
          "name": "Mindfulness-enhanced positive affect induction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Breathing Meditation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 180,
      "start_date": "2022-03-14",
      "completion_date": "2022-11-14",
      "has_results": false,
      "last_update_posted_date": "2023-03-22",
      "last_synced_at": "2026-09-21T07:10:00.792Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05619419"
    },
    {
      "nct_id": "NCT05920161",
      "title": "Influence of Stress on Encoding and Prediction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress",
        "Learning, Spatial"
      ],
      "interventions": [
        {
          "name": "Socially Evaluated Cold Pressor Test",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 106,
      "start_date": "2023-03-02",
      "completion_date": "2024-10-04",
      "has_results": true,
      "last_update_posted_date": "2025-10-15",
      "last_synced_at": "2026-09-21T07:10:00.792Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05920161"
    },
    {
      "nct_id": "NCT06417177",
      "title": "Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Aging",
        "Menopause",
        "Hypoxia",
        "Vasodilation"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Propranolol",
          "type": "DRUG"
        },
        {
          "name": "Gemtesa",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 70 Years · Female only"
      },
      "enrollment_count": 75,
      "start_date": "2024-06-03",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-09-10",
      "last_synced_at": "2026-09-21T07:10:00.792Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06417177"
    },
    {
      "nct_id": "NCT05096273",
      "title": "Retraining and Control Therapy (ReACT): Sense of Control and Symptom Expectations as Targets of a Treatment for PNES",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Convulsion, Non-Epileptic"
      ],
      "interventions": [
        {
          "name": "ReACT",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "11 Years to 18 Years"
      },
      "enrollment_count": 68,
      "start_date": "2021-10-28",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-26",
      "last_synced_at": "2026-09-21T07:10:00.792Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05096273"
    },
    {
      "nct_id": "NCT03933865",
      "title": "Acute Pain Management in Patients on Opioid Replacement Therapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Opioid-use Disorder",
        "Pain, Acute"
      ],
      "interventions": [
        {
          "name": "HYDROmorphone Injectable Solution",
          "type": "DRUG"
        },
        {
          "name": "Ketamine",
          "type": "DRUG"
        },
        {
          "name": "Placebos",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 1,
      "start_date": "2018-10-31",
      "completion_date": "2022-02-24",
      "has_results": false,
      "last_update_posted_date": "2022-10-10",
      "last_synced_at": "2026-09-21T07:10:00.792Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03933865"
    }
  ]
}