{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cold+Pressor+test&page=2", "query": { "intervention": "Cold Pressor test", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cold+Pressor+test&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-25T08:49:08.712Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05193968", "title": "Hot Flashes and Neurovascular Function in Women", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hot Flashes", "Menopause", "Vasomotor System; Labile" ], "interventions": [ { "name": "Sympathoexcitatory stressors", "type": "OTHER" }, { "name": "Sodium Nitroprusside", "type": "DRUG" }, { "name": "Acetylcholine", "type": "DRUG" }, { "name": "Terbutaline", "type": "DRUG" }, { "name": "Norepinephrine", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": "60 Years", "sex": "FEMALE", "summary": "40 Years to 60 Years · Female only" }, "enrollment_count": 120, "start_date": "2022-02-24", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-06-12", "last_synced_at": "2026-09-25T08:49:08.712Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT05193968" }, { "nct_id": "NCT02264262", "title": "Noninvasive Measurement of Sympathetic Nerve Activity in Healthy Volunteers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sympathetic Nerve Activity" ], "interventions": [ { "name": "Physiologic maneuvers", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Cedars-Sinai Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 4, "start_date": "2014-10", "completion_date": "2017-12", "has_results": false, "last_update_posted_date": "2020-01-14", "last_synced_at": "2026-09-25T08:49:08.712Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02264262" }, { "nct_id": "NCT01593579", "title": "Autonomic Phenotype Before and After Akt Inhibition", "overall_status": "WITHDRAWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Diagnosis of Melanoma" ], "interventions": [ { "name": "Autonomic Function Tests", "type": "BEHAVIORAL" }, { "name": "supine and standing catecholamines", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 0, "start_date": "2012-05", "completion_date": "2016-05", "has_results": false, "last_update_posted_date": "2014-12-23", "last_synced_at": "2026-09-25T08:49:08.712Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT01593579" }, { "nct_id": "NCT05795179", "title": "Stress & Self-Control Costs", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Self-Control" ], "interventions": [ { "name": "Cold-Pressor Task (CPT)", "type": "BEHAVIORAL" }, { "name": "Trier Social Stress Test (TSST)", "type": "BEHAVIORAL" }, { "name": "Modified Non-Stress CPT", "type": "BEHAVIORAL" }, { "name": "Modified Non-Stress TSST", "type": "BEHAVIORAL" }, { "name": "Functional Magnetic Resonance Imaging (fMRI)", "type": "DEVICE" } ], "intervention_types": [ "BEHAVIORAL", "DEVICE" ], "sponsor": "NYU Langone Health", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 300, "start_date": "2024-10-01", "completion_date": "2028-04-01", "has_results": false, "last_update_posted_date": "2026-03-11", "last_synced_at": "2026-09-25T08:49:08.712Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05795179" }, { "nct_id": "NCT02136784", "title": "Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Analgesic Response" ], "interventions": [ { "name": "morphine sulfate", "type": "DRUG" }, { "name": "hydrocodone", "type": "DRUG" }, { "name": "hydromorphone HCI", "type": "DRUG" }, { "name": "oxycodone", "type": "DRUG" }, { "name": "buprenorphine", "type": "DRUG" }, { "name": "oral tablet placebo", "type": "DRUG" }, { "name": "sublingual tablet placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "20 Years", "maximum_age": "50 Years", "sex": "MALE", "summary": "20 Years to 50 Years · Male only" }, "enrollment_count": 12, "start_date": "2014-04", "completion_date": "2014-12", "has_results": false, "last_update_posted_date": "2014-05-13", "last_synced_at": "2026-09-25T08:49:08.712Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02136784" }, { "nct_id": "NCT01996449", "title": "The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Eplerenone", "type": "DRUG" }, { "name": "Amlodipine", "type": "DRUG" }, { "name": "Microneurography", "type": "PROCEDURE" }, { "name": "Rhythmic handgrip exercise", "type": "PROCEDURE" }, { "name": "Sustained hand grip", "type": "PROCEDURE" }, { "name": "Forearm blood flow", "type": "PROCEDURE" }, { "name": "Arm cycling exercise", "type": "PROCEDURE" }, { "name": "Cold Pressor test", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 14, "start_date": "2013-07", "completion_date": "2021-04", "has_results": true, "last_update_posted_date": "2022-03-18", "last_synced_at": "2026-09-25T08:49:08.712Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01996449" }, { "nct_id": "NCT05619419", "title": "Study of Affect Induction for Lab Induced Pain in Healthy Undergraduates", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Meditation", "Pain", "Mindfulness", "Affect", "Emotion Regulation" ], "interventions": [ { "name": "Mindfulness-enhanced positive affect induction", "type": "BEHAVIORAL" }, { "name": "Breathing Meditation", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 180, "start_date": "2022-03-14", "completion_date": "2022-11-14", "has_results": false, "last_update_posted_date": "2023-03-22", "last_synced_at": "2026-09-25T08:49:08.712Z", "location_count": 1, "location_summary": "Denver, Colorado", "locations": [ { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT05619419" }, { "nct_id": "NCT06428890", "title": "Effect of 7 Days of Grape Seed Extract Supplementation on Cold Pressor Test and Muscle Metaboreflex in Individuals With Elevated and Stage 1 Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Prehypertension" ], "interventions": [ { "name": "Grape Seed Extract", "type": "DIETARY_SUPPLEMENT" }, { "name": "Placebo", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "California Baptist University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "30 Years", "sex": "MALE", "summary": "18 Years to 30 Years · Male only" }, "enrollment_count": 12, "start_date": "2022-03-01", "completion_date": "2024-04-01", "has_results": false, "last_update_posted_date": "2024-05-24", "last_synced_at": "2026-09-25T08:49:08.712Z", "location_count": 1, "location_summary": "Riverside, California", "locations": [ { "city": "Riverside", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06428890" }, { "nct_id": "NCT01576536", "title": "Genetic Variation in Platelet Aggregation", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Myocardial Infarction" ], "interventions": [], "intervention_types": [], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 117, "start_date": "2012-07", "completion_date": "2016-12", "has_results": true, "last_update_posted_date": "2019-06-05", "last_synced_at": "2026-09-25T08:49:08.712Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT01576536" }, { "nct_id": "NCT07110688", "title": "Novel Multimodal Neural, Physiological, and Behavioral Sensing and Machine Learning for Mental States", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "No Condition", "Study Mental State in Healthy Populations and Drug-resistant Epilepsy Patients With Existing iEEG" ], "interventions": [ { "name": "Virtual human social interaction", "type": "BEHAVIORAL" }, { "name": "Cold pressor test", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Southern California", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 90, "start_date": "2024-08-01", "completion_date": "2028-11-30", "has_results": false, "last_update_posted_date": "2025-10-01", "last_synced_at": "2026-09-25T08:49:08.712Z", "location_count": 2, "location_summary": "Downey, California • Los Angeles, California", "locations": [ { "city": "Downey", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07110688" } ] }