{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cold+Stress&page=2",
    "query": {
      "intervention": "Cold Stress",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cold+Stress&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-21T01:02:32.901Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07252947",
      "title": "Stress and Anxiety Effects on Valuation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Reward Value Level"
      ],
      "interventions": [
        {
          "name": "Socially Evaluated Cold Pressor Task (SECPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Non-Stressful Control Task",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 200,
      "start_date": "2025-12-18",
      "completion_date": "2028-11-07",
      "has_results": false,
      "last_update_posted_date": "2025-12-22",
      "last_synced_at": "2026-09-21T01:02:32.901Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07252947"
    },
    {
      "nct_id": "NCT06712602",
      "title": "PT150 Drug for Use in Alcohol Use Disorder",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Alcohol Use Disorder"
      ],
      "interventions": [
        {
          "name": "alcohol",
          "type": "DRUG"
        },
        {
          "name": "Stress-Induction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PT150",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Pop Test Oncology LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "21 Years to 55 Years"
      },
      "enrollment_count": 34,
      "start_date": "2025-02-01",
      "completion_date": "2028-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-16",
      "last_synced_at": "2026-09-21T01:02:32.901Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06712602"
    },
    {
      "nct_id": "NCT05926024",
      "title": "Long-Term Follow-Up in Women With Early Breast Cancer Three Years of More Post Primary Treatment",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Exercise Recall Patient Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health Behavior Questionnaire (HBQ)30 Patient Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Functional Assessment of Cancer Therapy-General (FACT-G) Patient Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) Patient Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes PROMIS Cognitive Function (Short Form 8a)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes Functional Assessment of Cancer-Gynecology Oncology Group-Neurotoxicity (FACT/GOG-NTX-12)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes PROMIS",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes FACT-Endocrine Symptoms",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes Penn Arthralgia Aging Survey",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes PRO-CTCAE (patient-reported CTCAE)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "p16 tumor suppressor gene",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "UNC Lineberger Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 253,
      "start_date": "2023-01-06",
      "completion_date": "2028-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-11",
      "last_synced_at": "2026-09-21T01:02:32.901Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05926024"
    },
    {
      "nct_id": "NCT01654289",
      "title": "University of Wisconsin Meditation & Exercise Cold Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Respiratory Infection"
      ],
      "interventions": [
        {
          "name": "Mindfulness Meditation",
          "type": "OTHER"
        },
        {
          "name": "Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "30 Years to 69 Years"
      },
      "enrollment_count": 413,
      "start_date": "2012-07",
      "completion_date": "2016-06",
      "has_results": true,
      "last_update_posted_date": "2018-11-07",
      "last_synced_at": "2026-09-21T01:02:32.901Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01654289"
    },
    {
      "nct_id": "NCT01552759",
      "title": "Appetite Hormones in Binge Eating Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Binge Eating Disorder"
      ],
      "interventions": [
        {
          "name": "Postprandial responses",
          "type": "PROCEDURE"
        },
        {
          "name": "Cold pressor test",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Test meal",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "New York Obesity and Nutrition Research Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 96,
      "start_date": "2007-05",
      "completion_date": "2012-01",
      "has_results": false,
      "last_update_posted_date": "2013-03-11",
      "last_synced_at": "2026-09-21T01:02:32.901Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01552759"
    },
    {
      "nct_id": "NCT01066923",
      "title": "Enhanced Firefighter Rehab Trial: The Role of Aspirin in Preventing Heat Stress Induced Platelet Activation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heat Stress Disorders"
      ],
      "interventions": [
        {
          "name": "Daily aspirin (ASA)",
          "type": "DRUG"
        },
        {
          "name": "Active cooling",
          "type": "OTHER"
        },
        {
          "name": "Acute aspirin (ASA)",
          "type": "DRUG"
        },
        {
          "name": "Passive cooling",
          "type": "OTHER"
        },
        {
          "name": "Daily placebo",
          "type": "DRUG"
        },
        {
          "name": "Acute placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Dave Hostler",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 124,
      "start_date": "2010-02",
      "completion_date": "2011-06",
      "has_results": true,
      "last_update_posted_date": "2017-11-13",
      "last_synced_at": "2026-09-21T01:02:32.901Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01066923"
    },
    {
      "nct_id": "NCT01048125",
      "title": "Characterization of Sympathetic Nerve Activity in Stress Cardiomyopathy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiomyopathy"
      ],
      "interventions": [
        {
          "name": "Sympathetic Nerve Activity",
          "type": "DEVICE"
        },
        {
          "name": "Mental Stress Test (Color Word Test)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "The Modified Oxford Technique for Baroreflex Sensitivity",
          "type": "DRUG"
        },
        {
          "name": "Cold Pressor Test",
          "type": "OTHER"
        },
        {
          "name": "Echocardiographic evaluation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "21 Years to 90 Years"
      },
      "enrollment_count": 2,
      "start_date": "2009-08",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2016-11-23",
      "last_synced_at": "2026-09-21T01:02:32.901Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01048125"
    },
    {
      "nct_id": "NCT04419831",
      "title": "Characterizing Subjective and Physiological Responses to Stress and Pain and Cognitive Learning and Executive Function",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pain Response, Stress, Trauma"
      ],
      "interventions": [
        {
          "name": "Yale Stress Pain Test (YSPT)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 81,
      "start_date": "2022-04-14",
      "completion_date": "2023-12-30",
      "has_results": false,
      "last_update_posted_date": "2024-02-07",
      "last_synced_at": "2026-09-21T01:02:32.901Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04419831"
    },
    {
      "nct_id": "NCT02349217",
      "title": "Mindfulness Based Couples Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Mindfulness-Based Relationship Enhancement (MBRE)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Self-Help Materials",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pain Assessment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Questionnaires",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Neurocognitive Tests",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cortisol Tests",
          "type": "PROCEDURE"
        },
        {
          "name": "Interviews",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2015-01-23",
      "completion_date": "2022-08-01",
      "has_results": false,
      "last_update_posted_date": "2022-08-24",
      "last_synced_at": "2026-09-21T01:02:32.901Z",
      "location_count": 2,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02349217"
    },
    {
      "nct_id": "NCT06349616",
      "title": "Cooling Strategies for Older Adults in the Heat",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging"
      ],
      "interventions": [
        {
          "name": "Intermittent cold-water hand and forearm immersion",
          "type": "OTHER"
        },
        {
          "name": "No intermittent cold-water hand and forearm immersion",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "65 Years to 100 Years"
      },
      "enrollment_count": 12,
      "start_date": "2024-05-01",
      "completion_date": "2025-07-21",
      "has_results": false,
      "last_update_posted_date": "2025-07-24",
      "last_synced_at": "2026-09-21T01:02:32.901Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06349616"
    }
  ]
}