{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Colesevelam+Hydrochloride&page=2", "query": { "intervention": "Colesevelam Hydrochloride", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 36, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Colesevelam+Hydrochloride&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Colesevelam+Hydrochloride&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-06T03:29:49.259Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07592858", "title": "Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "PFAS", "Environmental Exposures", "Occupational Exposure to Chemicals", "Military Exposure", "Burn Pit Exposure", "Forever Chemicals", "Hyperlipidemias, Hypercholesterolemia, Mixed Dyslipidemia", "Hyperlipidemia (E.G., Hypercholesterolemia)" ], "interventions": [ { "name": "Colesevelam", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Rhode Island", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "25 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "25 Years to 65 Years" }, "enrollment_count": 50, "start_date": "2026-07-01", "completion_date": "2029-09-29", "has_results": false, "last_update_posted_date": "2026-05-18", "last_synced_at": "2026-10-06T03:29:49.259Z", "location_count": 2, "location_summary": "Louisville, Kentucky • Augusta, Maine", "locations": [ { "city": "Louisville", "state": "Kentucky" }, { "city": "Augusta", "state": "Maine" } ], "official_url": "https://clinicaltrials.gov/study/NCT07592858" }, { "nct_id": "NCT00151762", "title": "Long-Term Study of Safety and Efficacy of WelChol® as an Additional Therapy in Patients With Type 2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 2 Diabetes" ], "interventions": [ { "name": "Colesevelam hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 780, "start_date": "2004-12", "completion_date": "2007-07", "has_results": false, "last_update_posted_date": "2008-01-09", "last_synced_at": "2026-10-06T03:29:49.259Z", "location_count": 62, "location_summary": "Birmingham, Alabama • Tuscumbia, Alabama • Jonesboro, Arkansas + 59 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tuscumbia", "state": "Alabama" }, { "city": "Jonesboro", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Searcy", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00151762" }, { "nct_id": "NCT00476710", "title": "Effects of Colesevelam HCl On Bile Acid Kinetics", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Type 2 Diabetes Mellitus", "Impaired Glucose Tolerance" ], "interventions": [ { "name": "Colesevelam HCl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "KineMed", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "40 Years to 60 Years" }, "enrollment_count": 36, "start_date": "2007-05", "completion_date": "2009-04", "has_results": false, "last_update_posted_date": "2015-04-01", "last_synced_at": "2026-10-06T03:29:49.259Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00476710" }, { "nct_id": "NCT00484419", "title": "Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose Blood Glucose Isn't Completely Controlled With Metformin", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 2 Diabetes", "Hyperlipidemia" ], "interventions": [ { "name": "Colesevelam HCl", "type": "DRUG" }, { "name": "rosiglitazone maleate", "type": "DRUG" }, { "name": "sitagliptin phosphate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 169, "start_date": "2007-05", "completion_date": "2008-04", "has_results": true, "last_update_posted_date": "2016-10-04", "last_synced_at": "2026-10-06T03:29:49.259Z", "location_count": 20, "location_summary": "La Mesa, California • Los Angeles, California • Los Gatos, California + 17 more", "locations": [ { "city": "La Mesa", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Gatos", "state": "California" }, { "city": "San Antonio", "state": "California" }, { "city": "Chiefland", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00484419" }, { "nct_id": "NCT00570739", "title": "Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 2 Diabetes Mellitus", "Hypercholesterolemia", "Pre-diabetes" ], "interventions": [ { "name": "Metformin HCl and Colesevelam Placebo", "type": "DRUG" }, { "name": "Metformin HCl tablets and Colesevelam tablets", "type": "DRUG" }, { "name": "Colesevelam placebo", "type": "DRUG" }, { "name": "Colesevelam", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "18 Years to 79 Years" }, "enrollment_count": 502, "start_date": "2007-11", "completion_date": "2009-05", "has_results": true, "last_update_posted_date": "2010-07-27", "last_synced_at": "2026-10-06T03:29:49.259Z", "location_count": 17, "location_summary": "Birmingham, Alabama • Los Gatos, California • Tarzana, California + 14 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Gatos", "state": "California" }, { "city": "Tarzana", "state": "California" }, { "city": "Ocala", "state": "Florida" }, { "city": "Pocatello", "state": "Idaho" } ], "official_url": "https://clinicaltrials.gov/study/NCT00570739" }, { "nct_id": "NCT07226440", "title": "Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Toxicant Exposure", "Firefighter", "Occupational Exposure to Chemicals" ], "interventions": [ { "name": "Colesevelam", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 50, "start_date": "2026-03-01", "completion_date": "2028-12", "has_results": false, "last_update_posted_date": "2026-04-24", "last_synced_at": "2026-10-06T03:29:49.259Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07226440" }, { "nct_id": "NCT00151749", "title": "WelChol® and Insulin in Treating Patients With Type 2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 2 Diabetes" ], "interventions": [ { "name": "Colesevelam hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 260, "start_date": "2004-06", "completion_date": "2005-12", "has_results": false, "last_update_posted_date": "2012-01-18", "last_synced_at": "2026-10-06T03:29:49.259Z", "location_count": 45, "location_summary": "Tuscumbia, Alabama • Sierra Vista, Arizona • Jonesboro, Arkansas + 42 more", "locations": [ { "city": "Tuscumbia", "state": "Alabama" }, { "city": "Sierra Vista", "state": "Arizona" }, { "city": "Jonesboro", "state": "Arkansas" }, { "city": "Searcy", "state": "Arkansas" }, { "city": "Carmichael", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00151749" }, { "nct_id": "NCT00789737", "title": "Welchol as Monotherapy for Type 2 Diabetes Mellitus", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "Welchol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 357, "start_date": "2009-01", "completion_date": "2011-12", "has_results": true, "last_update_posted_date": "2014-02-27", "last_synced_at": "2026-10-06T03:29:49.259Z", "location_count": 107, "location_summary": "Birmingham, Alabama • Montgomery, Alabama • Muscle Shoals, Alabama + 87 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Montgomery", "state": "Alabama" }, { "city": "Muscle Shoals", "state": "Alabama" }, { "city": "Green Valley", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00789737" }, { "nct_id": "NCT00147745", "title": "Effects of Colesevelam on How the Body Responds to Insulin in Patients With Type 2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Type 2 Diabetes" ], "interventions": [ { "name": "Colesevelam", "type": "DRUG" }, { "name": "Colesevelam matching placebo", "type": "DRUG" }, { "name": "Insulin glargine (Lantus)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 36, "start_date": "2005-06", "completion_date": "2008-01", "has_results": true, "last_update_posted_date": "2014-04-02", "last_synced_at": "2026-10-06T03:29:49.259Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00147745" }, { "nct_id": "NCT00789750", "title": "Colesevelam as Add-on to Pioglitazone Therapy for Type 2 Diabetes Mellitus", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "Colesevelam", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Pioglitazone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 562, "start_date": "2009-04", "completion_date": "2012-07", "has_results": true, "last_update_posted_date": "2017-06-26", "last_synced_at": "2026-10-06T03:29:49.259Z", "location_count": 141, "location_summary": "Birmingham, Alabama • Montgomery, Alabama • Green Valley, Arizona + 114 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Montgomery", "state": "Alabama" }, { "city": "Montgomery", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT00789750" } ] }