{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Colgate%C2%AE+Cavity+Protection+Toothpaste",
    "query": {
      "intervention": "Colgate® Cavity Protection Toothpaste"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-10T02:20:32.118Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02151058",
      "title": "A Clinical Trial to Test the Effect of a Marketed Mouth Rinse on Stain Removal",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Stain"
      ],
      "interventions": [
        {
          "name": "Colgate® Regular Cavity Protection",
          "type": "DRUG"
        },
        {
          "name": "Experimental Mouth Rinse",
          "type": "DRUG"
        },
        {
          "name": "Crest® 3D White Multi-Care Whitening Rinse, Glamorous White, Fresh Mint",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer and Personal Products Worldwide",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 227,
      "start_date": "2014-06",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2015-06-01",
      "last_synced_at": "2026-09-10T02:20:32.118Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02151058"
    },
    {
      "nct_id": "NCT04123665",
      "title": "A Phase 3 Clinical Study Investigating the Gingivitis Efficacy of a Test Dentifrice Containing Stannous Fluoride",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Stannous fluoride",
          "type": "DRUG"
        },
        {
          "name": "Sodium monofluorophosphate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 98,
      "start_date": "2013-05-28",
      "completion_date": "2013-12-11",
      "has_results": true,
      "last_update_posted_date": "2020-01-31",
      "last_synced_at": "2026-09-10T02:20:32.118Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04123665"
    },
    {
      "nct_id": "NCT01549587",
      "title": "Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis",
        "Pregnancy"
      ],
      "interventions": [
        {
          "name": "0.243% sodium fluoride",
          "type": "DRUG"
        },
        {
          "name": "toothbrush",
          "type": "DEVICE"
        },
        {
          "name": "dental floss",
          "type": "DEVICE"
        },
        {
          "name": "0.454% stannous fluoride",
          "type": "DRUG"
        },
        {
          "name": "0.07% Cetylpyridinium chloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Procter and Gamble",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 746,
      "start_date": "2012-02",
      "completion_date": "2014-04",
      "has_results": true,
      "last_update_posted_date": "2023-04-21",
      "last_synced_at": "2026-09-10T02:20:32.118Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01549587"
    },
    {
      "nct_id": "NCT01727258",
      "title": "A Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dentin Sensitivity"
      ],
      "interventions": [
        {
          "name": "Mouth Rinse",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride Toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Potassium Nitrate Toothpaste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Johnson & Johnson Consumer and Personal Products Worldwide",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 153,
      "start_date": "2012-12",
      "completion_date": "2013-02",
      "has_results": true,
      "last_update_posted_date": "2015-06-10",
      "last_synced_at": "2026-09-10T02:20:32.118Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01727258"
    },
    {
      "nct_id": "NCT04921371",
      "title": "Six Week Study of Experimental Mouth Rinses: Effect on Gingivitis and Plaque",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Gingivitis",
        "Plaque"
      ],
      "interventions": [
        {
          "name": "Colgate® Cavity Protection Toothpaste",
          "type": "OTHER"
        },
        {
          "name": "Listerine® Cool Mint®",
          "type": "OTHER"
        },
        {
          "name": "Concept Curve Winter Series Toothbrush",
          "type": "OTHER"
        },
        {
          "name": "5% Hydroalcohol Mouthrinse",
          "type": "OTHER"
        },
        {
          "name": "Mouthrinse Prototype 1",
          "type": "OTHER"
        },
        {
          "name": "Mouthrinse Prototype 2",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 157,
      "start_date": "2019-10-08",
      "completion_date": "2019-12-19",
      "has_results": false,
      "last_update_posted_date": "2023-09-28",
      "last_synced_at": "2026-09-10T02:20:32.118Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04921371"
    },
    {
      "nct_id": "NCT06798441",
      "title": "Determination of the Oral Irritation Potential of a Fluoride Rinse in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Brush Only",
          "type": "OTHER"
        },
        {
          "name": "Brush / Rinse (Jolly Rancher Prototype)",
          "type": "OTHER"
        },
        {
          "name": "Brush / Rinse (LISTERINE® Total Care Zero Alcohol)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer and Personal Products Worldwide",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "6 Years to 11 Years"
      },
      "enrollment_count": 161,
      "start_date": "2025-01-20",
      "completion_date": "2025-02-20",
      "has_results": false,
      "last_update_posted_date": "2025-03-12",
      "last_synced_at": "2026-09-10T02:20:32.118Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06798441"
    },
    {
      "nct_id": "NCT07160166",
      "title": "Determination of the Oral Irritation Potential of Two Alcohol-Free Rinses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Oral Health"
      ],
      "interventions": [
        {
          "name": "Prototype 1",
          "type": "OTHER"
        },
        {
          "name": "Prototype 2",
          "type": "OTHER"
        },
        {
          "name": "Marketed Comparator",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Kenvue Brands LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 169,
      "start_date": "2025-07-11",
      "completion_date": "2025-07-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-08",
      "last_synced_at": "2026-09-10T02:20:32.118Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07160166"
    }
  ]
}