{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Colgate+Cavity+Protection&page=2",
    "query": {
      "intervention": "Colgate Cavity Protection",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Colgate+Cavity+Protection&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T08:02:44.549Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06660069",
      "title": "A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Plaque",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste)",
          "type": "DRUG"
        },
        {
          "name": "CPC Mouthwash (Parodontax Active Gum Health Mouthwash)",
          "type": "DRUG"
        },
        {
          "name": "Regular Fluoride Toothpaste (Crest Cavity Protection)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 199,
      "start_date": "2024-11-18",
      "completion_date": "2025-03-11",
      "has_results": true,
      "last_update_posted_date": "2026-03-18",
      "last_synced_at": "2026-09-02T08:02:44.549Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06660069"
    },
    {
      "nct_id": "NCT04696536",
      "title": "A Twelve Week Study of Supervised Mouth Rinse and Flossing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Colgate Cavity Protection Toothpaste",
          "type": "OTHER"
        },
        {
          "name": "American Dental Association (ADA) Referenced Toothbrush",
          "type": "OTHER"
        },
        {
          "name": "5% Hydroalcohol Mouth Rinse",
          "type": "OTHER"
        },
        {
          "name": "REACH Dental Floss",
          "type": "OTHER"
        },
        {
          "name": "Alcohol-containing Essential Oil (AEO) Mouth Rinse (Listerine Cool Mint, marketed)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 149,
      "start_date": "2018-09-26",
      "completion_date": "2018-12-21",
      "has_results": false,
      "last_update_posted_date": "2021-09-28",
      "last_synced_at": "2026-09-02T08:02:44.549Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04696536"
    },
    {
      "nct_id": "NCT04750005",
      "title": "A Twelve Week Study of Virtually Supervised Mouth Rinse and Flossing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Listerine Cool Mint",
          "type": "OTHER"
        },
        {
          "name": "Colgate Cavity Protection Toothpaste",
          "type": "OTHER"
        },
        {
          "name": "Reach Unflavored Waxed Dental Floss",
          "type": "OTHER"
        },
        {
          "name": "American Dental Association (ADA) Ref Toothbrush",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 209,
      "start_date": "2020-10-23",
      "completion_date": "2021-02-01",
      "has_results": false,
      "last_update_posted_date": "2022-02-16",
      "last_synced_at": "2026-09-02T08:02:44.549Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04750005"
    },
    {
      "nct_id": "NCT07124533",
      "title": "Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Gingival Inflammation",
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Toothpaste Tablet",
          "type": "DRUG"
        },
        {
          "name": "Conventional Toothpaste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2026-12",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-10",
      "last_synced_at": "2026-09-02T08:02:44.549Z",
      "location_count": 2,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07124533"
    },
    {
      "nct_id": "NCT05526586",
      "title": "A Twelve Week Study of Prototypes Mouth Rinses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Colgate Cavity Protection Toothpaste",
          "type": "OTHER"
        },
        {
          "name": "Zero Alcohol Gum Prototype",
          "type": "OTHER"
        },
        {
          "name": "Alcohol Gum Prototype",
          "type": "OTHER"
        },
        {
          "name": "Listerine Cool Mint Antiseptic Mouthwash",
          "type": "OTHER"
        },
        {
          "name": "5% Hydroalcohol",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 192,
      "start_date": "2022-08-31",
      "completion_date": "2022-12-08",
      "has_results": false,
      "last_update_posted_date": "2023-09-05",
      "last_synced_at": "2026-09-02T08:02:44.549Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05526586"
    },
    {
      "nct_id": "NCT02366689",
      "title": "Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dental Plaque",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Triclosan/fluoride toothpaste",
          "type": "DRUG"
        },
        {
          "name": "stannous fluoride toothpaste",
          "type": "DRUG"
        },
        {
          "name": "fluoride only toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Cetylpyridinium chloride mouthwash",
          "type": "DRUG"
        },
        {
          "name": "Fluoride only mouthwash",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 179,
      "start_date": "2014-06",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2016-03-30",
      "last_synced_at": "2026-09-02T08:02:44.549Z",
      "location_count": 1,
      "location_summary": "Cedar Knolls, New Jersey",
      "locations": [
        {
          "city": "Cedar Knolls",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02366689"
    },
    {
      "nct_id": "NCT04050722",
      "title": "A Clinical Study Investigating the Efficacy of a Stannous Fluoride Dentifrice in Improving Gingival Health After Twice Daily Use for 3 Weeks",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Sensodyne Repair and Protect",
          "type": "DRUG"
        },
        {
          "name": "Colgate Cavity Protection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 130,
      "start_date": "2019-10-07",
      "completion_date": "2019-11-13",
      "has_results": true,
      "last_update_posted_date": "2020-11-19",
      "last_synced_at": "2026-09-02T08:02:44.549Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04050722"
    },
    {
      "nct_id": "NCT07225478",
      "title": "Clinical Study to Evaluate the Tooth Whitening Efficacy of a New NextGen In-office Whitening System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Health Adult Subjects"
      ],
      "interventions": [
        {
          "name": "Beaming White",
          "type": "DRUG"
        },
        {
          "name": "Philips Zoom Professional Whitening Treatment",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Opalescence Boost PF",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Fluoride Toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Soft Manual Toothbrush",
          "type": "DEVICE"
        },
        {
          "name": "CP LED",
          "type": "DEVICE"
        },
        {
          "name": "Gingival Barrier",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "COMBINATION_PRODUCT",
        "DEVICE"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 180,
      "start_date": "2025-10-31",
      "completion_date": "2025-12-21",
      "has_results": false,
      "last_update_posted_date": "2026-01-08",
      "last_synced_at": "2026-09-02T08:02:44.549Z",
      "location_count": 1,
      "location_summary": "Melbourne, Florida",
      "locations": [
        {
          "city": "Melbourne",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07225478"
    },
    {
      "nct_id": "NCT00941668",
      "title": "Evaluate Inflammation Caused by Gingivitis in Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Triclosan/Copolymer/fluoride toothpaste",
          "type": "DRUG"
        },
        {
          "name": "sodium monofluorophosphate toothpaste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 49,
      "start_date": "2007-01",
      "completion_date": "2008-08",
      "has_results": true,
      "last_update_posted_date": "2015-08-27",
      "last_synced_at": "2026-09-02T08:02:44.549Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00941668"
    },
    {
      "nct_id": "NCT06150573",
      "title": "A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dentin Sensitivity",
        "Oral Hygiene"
      ],
      "interventions": [
        {
          "name": "Test Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Reference Dentifrice (Aquafresh Cavity Protection)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 160,
      "start_date": "2023-11-27",
      "completion_date": "2024-07-18",
      "has_results": true,
      "last_update_posted_date": "2025-07-24",
      "last_synced_at": "2026-09-02T08:02:44.549Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06150573"
    }
  ]
}