{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Combination+nicotine+patch+and+nicotine+mini-lozenge+treatment",
    "query": {
      "intervention": "Combination nicotine patch and nicotine mini-lozenge treatment"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-01T23:14:38.052Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02564315",
      "title": "The Long-Term Quitting (Smoking Cessation) Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Nicotine Mini-Lozenge for 11 Months",
          "type": "DRUG"
        },
        {
          "name": "Preparation Phase Behavioral Reduction Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Preparation Phase Recycling Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Preparation Phase Control Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation Phase Supportive Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation Phase Skill Training Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation Phase Brief Information",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation Phase Nicotine Patch + Nicotine Mini-Lozenge",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1154,
      "start_date": "2015-10-30",
      "completion_date": "2019-11-05",
      "has_results": false,
      "last_update_posted_date": "2020-02-17",
      "last_synced_at": "2026-09-01T23:14:38.052Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02564315"
    },
    {
      "nct_id": "NCT04188873",
      "title": "Cessation Screening Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Preparation Varenicline and Standard Duration Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Preparation Varenicline and Extended Duration Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Standard Duration Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Extended Duration Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Preparation Combination NRT and Standard Duration Combination NRT",
          "type": "DRUG"
        },
        {
          "name": "Preparation Combination NRT and Extended Duration Combination NRT",
          "type": "DRUG"
        },
        {
          "name": "Standard Duration Combination NRT",
          "type": "DRUG"
        },
        {
          "name": "Extended Duration Combination NRT",
          "type": "DRUG"
        },
        {
          "name": "Intensive Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minimal Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 538,
      "start_date": "2020-12-10",
      "completion_date": "2025-05-08",
      "has_results": true,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-09-01T23:14:38.052Z",
      "location_count": 2,
      "location_summary": "Madison, Wisconsin • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04188873"
    },
    {
      "nct_id": "NCT04969198",
      "title": "UW Withdraw From Tobacco Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tobacco Dependence"
      ],
      "interventions": [
        {
          "name": "Combination nicotine replacement therapy (Nicotine patch + nicotine mini-lozenge)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 232,
      "start_date": "2021-07-13",
      "completion_date": "2022-09-21",
      "has_results": true,
      "last_update_posted_date": "2025-05-08",
      "last_synced_at": "2026-09-01T23:14:38.052Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04969198"
    },
    {
      "nct_id": "NCT04199117",
      "title": "Health Systems Reach Interventions Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking, Cigarette",
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Combination nicotine patch and nicotine mini-lozenge treatment",
          "type": "DRUG"
        },
        {
          "name": "Monetary incentives for initiating treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Automated tailored outreach",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Care management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Wisconsin Tobacco Quit Line referral",
          "type": "OTHER"
        },
        {
          "name": "Primary care provider referral",
          "type": "OTHER"
        },
        {
          "name": "Untailored outreach",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Multiple smoking cessation coaching calls",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 210,
      "start_date": "2020-03-11",
      "completion_date": "2024-10-16",
      "has_results": true,
      "last_update_posted_date": "2025-09-24",
      "last_synced_at": "2026-09-01T23:14:38.052Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04199117"
    },
    {
      "nct_id": "NCT02301403",
      "title": "A Comparative Effectiveness RCT of Optimized Cessation Treatments",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "in-person counseling and quitline counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Preparation Nicotine Mini-Lozenges",
          "type": "DRUG"
        },
        {
          "name": "Combination NRT (nicotine patch + nicotine mini-lozenges)",
          "type": "DRUG"
        },
        {
          "name": "Intensive In-Person Cessation Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Extended Maintenance Counseling Calls",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Automated Adherence Calls",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 623,
      "start_date": "2015-01",
      "completion_date": "2018-02",
      "has_results": true,
      "last_update_posted_date": "2020-05-13",
      "last_synced_at": "2026-09-01T23:14:38.052Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02301403"
    },
    {
      "nct_id": "NCT06966362",
      "title": "Varenicline for Smoking Reduction in Veterans Not Ready To Quit",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Veterans",
        "Tobacco Use Disorder",
        "Cigarette Smoking",
        "Tobacco Dependence"
      ],
      "interventions": [
        {
          "name": "Motivation-Phase Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Motivation-Phase Nicotine Mini-Lozenge",
          "type": "DRUG"
        },
        {
          "name": "Cessation-Phase Combination Nicotine Replacement Therapy (NRT)",
          "type": "DRUG"
        },
        {
          "name": "Cessation-Phase Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Motivation-Phase Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation-Phase Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2026-08-17",
      "completion_date": "2030-06-28",
      "has_results": false,
      "last_update_posted_date": "2026-08-31",
      "last_synced_at": "2026-09-01T23:14:38.052Z",
      "location_count": 4,
      "location_summary": "San Diego, California • Minneapolis, Minnesota • Durham, North Carolina + 1 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06966362"
    }
  ]
}