{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Comparison+Group",
    "query": {
      "intervention": "Comparison Group"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 3619,
    "total_pages": 362,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Comparison+Group&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T03:20:27.740Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05211843",
      "title": "Saliva Insulin as Biomarker of Risk Factors for Metabolic Dysregulation and Caries",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Caries",
        "Metabolomic Profile"
      ],
      "interventions": [
        {
          "name": "Drinking water",
          "type": "OTHER"
        },
        {
          "name": "Apple juice",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Jodi Stookey",
      "sponsor_class": "OTHER_GOV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "5 Years to 10 Years"
      },
      "enrollment_count": 105,
      "start_date": "2022-10-12",
      "completion_date": "2024-01-29",
      "has_results": false,
      "last_update_posted_date": "2026-02-25",
      "last_synced_at": "2026-09-02T03:20:27.740Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05211843"
    },
    {
      "nct_id": "NCT01453790",
      "title": "Parent Specific Depression Education and Motivation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depressive Symptoms"
      ],
      "interventions": [
        {
          "name": "Parent-Specific Depression Education and Motivation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "General Depression Education-Motivation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 104,
      "start_date": "2011-04",
      "completion_date": "2012-01",
      "has_results": false,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-09-02T03:20:27.740Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01453790"
    },
    {
      "nct_id": "NCT02870725",
      "title": "CBT Depression Intervention for Co-Occurring Chronic Headache",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Headaches Chronic",
        "Migraine Disorders"
      ],
      "interventions": [
        {
          "name": "CBT Individual Psychotherapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Georgia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 22,
      "start_date": "2016-11",
      "completion_date": "2017-07-01",
      "has_results": false,
      "last_update_posted_date": "2017-07-06",
      "last_synced_at": "2026-09-02T03:20:27.740Z",
      "location_count": 2,
      "location_summary": "Athens, Michigan • Detroit, Michigan",
      "locations": [
        {
          "city": "Athens",
          "state": "Michigan"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02870725"
    },
    {
      "nct_id": "NCT04280276",
      "title": "TruGraf Utilization in High IPV Levels",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Kidney Transplant; Complications"
      ],
      "interventions": [
        {
          "name": "TruGraf test",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2020-03-02",
      "completion_date": "2022-03-01",
      "has_results": false,
      "last_update_posted_date": "2024-12-16",
      "last_synced_at": "2026-09-02T03:20:27.740Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04280276"
    },
    {
      "nct_id": "NCT03079713",
      "title": "Handheld Vibrator Versus Topical Eye Drops as Anesthesia for Intravitreal Injections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain Control During Intravitreal Injections"
      ],
      "interventions": [
        {
          "name": "Handheld vibrator triggered during intravitreal injection for wet ARMD",
          "type": "DEVICE"
        },
        {
          "name": "Normal eye esthesiometry with and without vibration",
          "type": "DEVICE"
        },
        {
          "name": "Handheld vibrator not triggered during intravitreal injection for wet ARMD",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wills Eye",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2017-04-12",
      "completion_date": "2019-03-20",
      "has_results": false,
      "last_update_posted_date": "2019-05-09",
      "last_synced_at": "2026-09-02T03:20:27.740Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03079713"
    },
    {
      "nct_id": "NCT01587313",
      "title": "A Comparison of Various Combinations of BiDil Capsules and BiDil Tablets in Healthy Human Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Isosorbide dinitrate / hydralazine capsules",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Arbor Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 36,
      "start_date": "2012-04",
      "completion_date": "2012-05",
      "has_results": false,
      "last_update_posted_date": "2015-08-06",
      "last_synced_at": "2026-09-02T03:20:27.740Z",
      "location_count": 1,
      "location_summary": "Hackensack, New Jersey",
      "locations": [
        {
          "city": "Hackensack",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01587313"
    },
    {
      "nct_id": "NCT02750813",
      "title": "ACUVUE® OASYS® 1-DAY vs DAILIES TOTAL1®",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Error"
      ],
      "interventions": [
        {
          "name": "Delefilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Senofilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon, a Novartis Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 252,
      "start_date": "2016-04-27",
      "completion_date": "2016-08-17",
      "has_results": true,
      "last_update_posted_date": "2018-07-02",
      "last_synced_at": "2026-09-02T03:20:27.740Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02750813"
    },
    {
      "nct_id": "NCT05844124",
      "title": "Impact of Different Exercise Programs on Knee OA",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Knee Osteoarthritis",
        "Arthritis",
        "Joint Diseases",
        "Musculoskeletal Diseases",
        "Rheumatic Diseases"
      ],
      "interventions": [
        {
          "name": "Exercise for Knee Osteoarthritis Recommendations (Control group)",
          "type": "OTHER"
        },
        {
          "name": "Exercise for Knee Osteoarthritis -(LBPP supported low-load treadmill Walking)",
          "type": "OTHER"
        },
        {
          "name": "Exercise for Knee Osteoarthritis - (Aquatic Walking)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 60,
      "start_date": "2023-04-01",
      "completion_date": "2025-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-01",
      "last_synced_at": "2026-09-02T03:20:27.740Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05844124"
    },
    {
      "nct_id": "NCT05976789",
      "title": "A Feasibility Study of a Novel, Fully Remote Counseling and Sound Therapy Program for Hyperacusis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hyperacusis"
      ],
      "interventions": [
        {
          "name": "Sound therapy using low-level background sound",
          "type": "DEVICE"
        },
        {
          "name": "Remote counseling using HAT-Online",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sound therapy using successive approximations",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Augustana College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2023-12-18",
      "completion_date": "2026-05",
      "has_results": false,
      "last_update_posted_date": "2024-04-17",
      "last_synced_at": "2026-09-02T03:20:27.740Z",
      "location_count": 1,
      "location_summary": "Rock Island, Illinois",
      "locations": [
        {
          "city": "Rock Island",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05976789"
    },
    {
      "nct_id": "NCT03778515",
      "title": "Novel Quantitative MRI for Axial Spondyloarthritis",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spondylitis, Ankylosing"
      ],
      "interventions": [
        {
          "name": "MRI",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2020-01-15",
      "completion_date": "2021-07-31",
      "has_results": false,
      "last_update_posted_date": "2022-08-31",
      "last_synced_at": "2026-09-02T03:20:27.740Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03778515"
    }
  ]
}