{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Control+Group+%28Optimal+Medical+Therapy%29",
    "query": {
      "intervention": "Control Group (Optimal Medical Therapy)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 37,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Control+Group+%28Optimal+Medical+Therapy%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-16T20:41:58.361Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07754526",
      "title": "OCM™ Treatment With Routine Care in Venous Leg Ulcers Compared to Routine Care Treatment Alone.",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Leg Ulcer (VLU)"
      ],
      "interventions": [
        {
          "name": "Omeza OCM™ Wound Matrix",
          "type": "DEVICE"
        },
        {
          "name": "Routine Care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Omeza, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 254,
      "start_date": "2026-08",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-08-10",
      "last_synced_at": "2026-09-16T20:41:58.361Z",
      "location_count": 1,
      "location_summary": "Lake Success, New York",
      "locations": [
        {
          "city": "Lake Success",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07754526"
    },
    {
      "nct_id": "NCT02052817",
      "title": "Randomized, Prospective Evaluation of the Toad Brace in Plantar Ulcer Off-loading and Healing",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot",
        "Pedal Ulcers"
      ],
      "interventions": [
        {
          "name": "Optimal Medical Therapy Debridement + Toad Brace",
          "type": "DEVICE"
        },
        {
          "name": "Optimal Medical Therapy - Debridement",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Toad Medical Corporation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2013-12",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2014-02-03",
      "last_synced_at": "2026-09-16T20:41:58.361Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02052817"
    },
    {
      "nct_id": "NCT01775436",
      "title": "Palliative Care in People Living With HIV/AIDS: Integrating Into Standard of Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV"
      ],
      "interventions": [
        {
          "name": "FAmily-CEntered Advance Care Planning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Healthy Living Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Children's National Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 444,
      "start_date": "2013-10-13",
      "completion_date": "2017-03-28",
      "has_results": false,
      "last_update_posted_date": "2020-07-15",
      "last_synced_at": "2026-09-16T20:41:58.361Z",
      "location_count": 5,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01775436"
    },
    {
      "nct_id": "NCT03250247",
      "title": "Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Deep Vein Thrombosis",
        "Venous Stasis",
        "Venous Insufficiency",
        "Venous Leg Ulcer",
        "Venous Reflux",
        "Post Thrombotic Syndrome"
      ],
      "interventions": [
        {
          "name": "Stents",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 225,
      "start_date": "2018-07-02",
      "completion_date": "2026-04-27",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-09-16T20:41:58.361Z",
      "location_count": 29,
      "location_summary": "Orange, California • San Francisco, California • New Haven, Connecticut + 23 more",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03250247"
    },
    {
      "nct_id": "NCT03951064",
      "title": "Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity, Morbid",
        "Ventilator-Induced Lung Injury",
        "Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Esophageal balloon",
          "type": "DEVICE"
        },
        {
          "name": "Intervention Spontaneous Breathing Trial (SBT) and Extubation",
          "type": "PROCEDURE"
        },
        {
          "name": "Control Spontaneous Breathing Trial and Extubation",
          "type": "PROCEDURE"
        },
        {
          "name": "Intervention Weaning after Tracheostomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Control Weaning after Tracheostomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2021-03-31",
      "completion_date": "2022-12-06",
      "has_results": true,
      "last_update_posted_date": "2024-06-05",
      "last_synced_at": "2026-09-16T20:41:58.361Z",
      "location_count": 2,
      "location_summary": "Chapel Hill, North Carolina • Greenville, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Greenville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03951064"
    },
    {
      "nct_id": "NCT03716349",
      "title": "Esthetics of Dental Composite and Adhesive System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cavities of Teeth"
      ],
      "interventions": [
        {
          "name": "Pulp vitality testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Photos",
          "type": "OTHER"
        },
        {
          "name": "local and/or topical anesthetic",
          "type": "DRUG"
        },
        {
          "name": "rubber dam",
          "type": "DEVICE"
        },
        {
          "name": "tooth surface cleaned",
          "type": "OTHER"
        },
        {
          "name": "enamel margins",
          "type": "PROCEDURE"
        },
        {
          "name": "Adhesive Systems",
          "type": "PROCEDURE"
        },
        {
          "name": "cavity preparation",
          "type": "PROCEDURE"
        },
        {
          "name": "Shade selection using Easy Shade 5",
          "type": "OTHER"
        },
        {
          "name": "Light Curing",
          "type": "PROCEDURE"
        },
        {
          "name": "Contoured and polished",
          "type": "PROCEDURE"
        },
        {
          "name": "Consent",
          "type": "OTHER"
        },
        {
          "name": "Health Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "xray",
          "type": "RADIATION"
        },
        {
          "name": "Release of medical information signed",
          "type": "OTHER"
        },
        {
          "name": "Oral Exam",
          "type": "OTHER"
        },
        {
          "name": "Teeth Assessment",
          "type": "OTHER"
        },
        {
          "name": "Clinical Assessment",
          "type": "OTHER"
        },
        {
          "name": "Tokuyama Universal Bond",
          "type": "DEVICE"
        },
        {
          "name": "ScotchBond",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER",
        "DRUG",
        "DEVICE",
        "PROCEDURE",
        "RADIATION"
      ],
      "sponsor": "Erica Teixeira",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2019-01-01",
      "completion_date": "2025-11-20",
      "has_results": true,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-09-16T20:41:58.361Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03716349"
    },
    {
      "nct_id": "NCT03639051",
      "title": "Evaluation of the Safety and Efficacy of TLD in Patients with COPD",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COPD"
      ],
      "interventions": [
        {
          "name": "Targeted Lung Denervation (TLD)",
          "type": "DEVICE"
        },
        {
          "name": "Optimal Medical Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Nuvaira, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 464,
      "start_date": "2019-05-23",
      "completion_date": "2028-09",
      "has_results": false,
      "last_update_posted_date": "2024-11-14",
      "last_synced_at": "2026-09-16T20:41:58.361Z",
      "location_count": 20,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Sacramento, California + 17 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03639051"
    },
    {
      "nct_id": "NCT00945659",
      "title": "Use of Continuous Glucose Sensors by Adolescents With Inadequate Diabetic Control",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 1 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Continuous Glucose Sensor",
          "type": "DEVICE"
        },
        {
          "name": "Standard Care",
          "type": "OTHER"
        },
        {
          "name": "CGS + Behavior Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Nemours Children's Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "11 Years to 16 Years"
      },
      "enrollment_count": 116,
      "start_date": "2009-08",
      "completion_date": "2017-06-30",
      "has_results": true,
      "last_update_posted_date": "2018-09-10",
      "last_synced_at": "2026-09-16T20:41:58.361Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00945659"
    },
    {
      "nct_id": "NCT00754741",
      "title": "Multi-arm Intervention Diabetes Adherence Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "Adherence information",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Adherence information plus motivational interviewing",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1692,
      "start_date": "2008-07",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2015-05-08",
      "last_synced_at": "2026-09-16T20:41:58.361Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00754741"
    },
    {
      "nct_id": "NCT05806138",
      "title": "A Study of Vericiguat in People With Breast Cancer and Cancer Therapy-Related Cardiac Dysfunction",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer",
        "Cardiac Dysfunction"
      ],
      "interventions": [
        {
          "name": "Vericiguat",
          "type": "DRUG"
        },
        {
          "name": "Optimal medical therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 21,
      "start_date": "2023-07-17",
      "completion_date": "2028-07-17",
      "has_results": false,
      "last_update_posted_date": "2026-08-03",
      "last_synced_at": "2026-09-16T20:41:58.361Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05806138"
    }
  ]
}