{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Control+Rationale&page=16",
    "query": {
      "intervention": "Control Rationale",
      "page": 16
    },
    "page_size": 10
  },
  "pagination": {
    "page": 16,
    "page_size": 10,
    "total_count": 442,
    "total_pages": 45,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Control+Rationale&page=17&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Control+Rationale&page=15&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-20T03:28:29.448Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04477304",
      "title": "Application of Economics & Social Psychology to Improve Opioid Prescribing Safety Trial 1: EHR Nudges",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Abuse, Unspecified"
      ],
      "interventions": [
        {
          "name": "Opioid Naive, OR",
          "type": "BEHAVIORAL"
        },
        {
          "name": "At-risk for long-term use, OR",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Long-term opioid recipient",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 555,
      "start_date": "2020-12-01",
      "completion_date": "2023-08-06",
      "has_results": true,
      "last_update_posted_date": "2025-08-07",
      "last_synced_at": "2026-10-20T03:28:29.448Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04477304"
    },
    {
      "nct_id": "NCT04059549",
      "title": "Building and Pilot Testing a Couples-based Smartphone Systems to Address Alcohol Use Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Use Disorder",
        "Couples",
        "Behavior, Addictive"
      ],
      "interventions": [
        {
          "name": "PartnerCHESS",
          "type": "BEHAVIORAL"
        },
        {
          "name": "A-CHESS",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 68,
      "start_date": "2020-11-17",
      "completion_date": "2021-09-29",
      "has_results": true,
      "last_update_posted_date": "2025-04-22",
      "last_synced_at": "2026-10-20T03:28:29.448Z",
      "location_count": 1,
      "location_summary": "Fall River, Massachusetts",
      "locations": [
        {
          "city": "Fall River",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04059549"
    },
    {
      "nct_id": "NCT04944784",
      "title": "A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Amyotrophic Lateral Sclerosis"
      ],
      "interventions": [
        {
          "name": "Reldesemtiv",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cytokinetics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 489,
      "start_date": "2021-08-16",
      "completion_date": "2023-07-18",
      "has_results": true,
      "last_update_posted_date": "2024-12-05",
      "last_synced_at": "2026-10-20T03:28:29.448Z",
      "location_count": 36,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Orange, California + 30 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04944784"
    },
    {
      "nct_id": "NCT03046017",
      "title": "Neuromodulation of Lidocaine Cream Effect on Chronic Pain Patients",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Low Back Pain"
      ],
      "interventions": [
        {
          "name": "tDCS",
          "type": "DEVICE"
        },
        {
          "name": "Lidocaine cream",
          "type": "OTHER"
        },
        {
          "name": "Control cream",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 90,
      "start_date": "2017-08-30",
      "completion_date": "2023-05",
      "has_results": false,
      "last_update_posted_date": "2023-01-03",
      "last_synced_at": "2026-10-20T03:28:29.448Z",
      "location_count": 1,
      "location_summary": "Charlestown, Massachusetts",
      "locations": [
        {
          "city": "Charlestown",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03046017"
    },
    {
      "nct_id": "NCT01574118",
      "title": "Enhancing Exposure Therapy for Post-traumatic Stress Disorder",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Posttraumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Revisiting the Trauma memories",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Processing the trauma memories",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Psychoeducation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Trauma Memory Retrieval Trial",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exposure to video clips related to the patient's trauma",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Breathing retraining",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exposure Homework",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Compound extinction",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 27,
      "start_date": "2012-04",
      "completion_date": "2020-03",
      "has_results": false,
      "last_update_posted_date": "2022-08-29",
      "last_synced_at": "2026-10-20T03:28:29.448Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01574118"
    },
    {
      "nct_id": "NCT05638620",
      "title": "Dual Sympathetic Blocks for Patients Experiencing Sympathetically-Mediated Symptoms From Long COVID",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Post Acute COVID-19 Syndrome",
        "Long COVID",
        "Long Covid19",
        "COVID-19 Recurrent",
        "Post-Acute COVID-19",
        "Post-Acute COVID-19 Infection",
        "SARS-CoV2 Infection",
        "Post Acute Sequelae of COVID-19",
        "Dysautonomia",
        "Dysautonomia Like Disorder",
        "Dysautonomia Orthostatic Hypotension Syndrome",
        "Post COVID-19 Condition",
        "Post-COVID Syndrome",
        "Post COVID-19 Condition, Unspecified",
        "Post-COVID-19 Syndrome"
      ],
      "interventions": [
        {
          "name": "stellate ganglion block with 0.5% bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jonathann Kuo, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 20,
      "start_date": "2023-01-03",
      "completion_date": "2023-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-03-13",
      "last_synced_at": "2026-10-20T03:28:29.448Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05638620"
    },
    {
      "nct_id": "NCT03039738",
      "title": "Surveillance Monitoring as an Alternative to Telemetry",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Telemetry",
        "Patient Monitoring"
      ],
      "interventions": [
        {
          "name": "Vital Sync IM & VPMP (Surveillance Monitoring)",
          "type": "DEVICE"
        },
        {
          "name": "Telemetry Monitoring",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic - MITG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 206,
      "start_date": "2017-04-03",
      "completion_date": "2018-01-04",
      "has_results": true,
      "last_update_posted_date": "2019-05-13",
      "last_synced_at": "2026-10-20T03:28:29.448Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03039738"
    },
    {
      "nct_id": "NCT06734286",
      "title": "Working Memory Training in Patients with Mild Cognitive Impairment",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment (MCI)"
      ],
      "interventions": [
        {
          "name": "CogMed",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "St. Joseph's Hospital and Medical Center, Phoenix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2024-09-16",
      "completion_date": "2025-09-30",
      "has_results": false,
      "last_update_posted_date": "2024-12-16",
      "last_synced_at": "2026-10-20T03:28:29.448Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06734286"
    },
    {
      "nct_id": "NCT03368183",
      "title": "Acute Kidney Injury Standardized Clinical Assessment and Management Plan for Renal Replacement Initiation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Kidney Injury"
      ],
      "interventions": [
        {
          "name": "Care delivery algorithim",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 224,
      "start_date": "2017-07-01",
      "completion_date": "2022-02-28",
      "has_results": false,
      "last_update_posted_date": "2022-08-10",
      "last_synced_at": "2026-10-20T03:28:29.448Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03368183"
    },
    {
      "nct_id": "NCT07424378",
      "title": "Epoprostenol Plus Conventional Therapy in COld and Frostbite Injury (ECCO)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Frostbite"
      ],
      "interventions": [
        {
          "name": "Standard of care plus Epoprostenol infusion for 8 hours (hrs) per day up to 5 days maximum",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care + Placebo (Normal Saline)infusion for 8 hours per day up to 5 days maximum",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2026-02",
      "completion_date": "2028-11",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-10-20T03:28:29.448Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07424378"
    }
  ]
}