{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Control+monofocal+intraocular+lens",
    "query": {
      "intervention": "Control monofocal intraocular lens"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 15,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Control+monofocal+intraocular+lens&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-27T20:53:24.637Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07317661",
      "title": "Effectiveness of a Large Language Model-Based Educational Tool on Intraocular Lens Options",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eye Disorders",
        "Cataract Extraction",
        "Cataract and IOL Surgery",
        "Cataract Surgery Experience",
        "Cataract Surgery",
        "Intraocular Lens"
      ],
      "interventions": [
        {
          "name": "LLM-based Education",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2026-01",
      "completion_date": "2026-06",
      "has_results": false,
      "last_update_posted_date": "2026-01-05",
      "last_synced_at": "2026-09-27T20:53:24.637Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07317661"
    },
    {
      "nct_id": "NCT07218796",
      "title": "Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cataract",
        "Glaucoma",
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "Bimatoprost Implant System",
          "type": "DRUG"
        },
        {
          "name": "SpyGlass IOL",
          "type": "DEVICE"
        },
        {
          "name": "Timolol Maleate Ophthalmic Solution, 0.5%",
          "type": "DRUG"
        },
        {
          "name": "Commercial IOL",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "SpyGlass Pharma, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2025-10-28",
      "completion_date": "2031-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-09-27T20:53:24.637Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07218796"
    },
    {
      "nct_id": "NCT03500198",
      "title": "Clinical Investigation of the Next Generation Intraocular Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cataract"
      ],
      "interventions": [
        {
          "name": "Investigational Intraocular Lens Device #1: Next Generation TECNIS IOL",
          "type": "DEVICE"
        },
        {
          "name": "Control Monofocal Intraocular Lens: TECNIS Monofocal IOL",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Surgical Vision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 247,
      "start_date": "2018-06-28",
      "completion_date": "2019-06-05",
      "has_results": true,
      "last_update_posted_date": "2020-06-25",
      "last_synced_at": "2026-09-27T20:53:24.637Z",
      "location_count": 10,
      "location_summary": "Torrance, California • Bradenton, Florida • Jacksonville, Florida + 6 more",
      "locations": [
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Sioux City",
          "state": "Iowa"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03500198"
    },
    {
      "nct_id": "NCT03633695",
      "title": "Clinical Evaluation of a Small Aperture Extended Depth of Focus Intraocular Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cataract",
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "IC-8 IOL Group",
          "type": "DEVICE"
        },
        {
          "name": "Control Group",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "AcuFocus, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 453,
      "start_date": "2018-12-04",
      "completion_date": "2020-10-15",
      "has_results": true,
      "last_update_posted_date": "2022-10-24",
      "last_synced_at": "2026-09-27T20:53:24.637Z",
      "location_count": 21,
      "location_summary": "Tucson, Arizona • Bakersfield, California • Laguna Hills, California + 18 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Los Altos",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03633695"
    },
    {
      "nct_id": "NCT06120842",
      "title": "Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Cataract",
        "Glaucoma",
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "Bimatoprost Implant System (High Dose)",
          "type": "DRUG"
        },
        {
          "name": "Bimatoprost Implant System (Low Dose)",
          "type": "DRUG"
        },
        {
          "name": "Timolol Maleate Ophthalmic Solution, 0.5%",
          "type": "DRUG"
        },
        {
          "name": "Commercially Available Aspheric Monofocal Non-Yellow Chromophore IOL",
          "type": "DEVICE"
        },
        {
          "name": "SpyGlass IOL",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "SpyGlass Pharma, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 201,
      "start_date": "2023-10-13",
      "completion_date": "2027-11",
      "has_results": false,
      "last_update_posted_date": "2025-08-22",
      "last_synced_at": "2026-09-27T20:53:24.637Z",
      "location_count": 1,
      "location_summary": "Glendale, Arizona",
      "locations": [
        {
          "city": "Glendale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06120842"
    },
    {
      "nct_id": "NCT01539239",
      "title": "Safety & Effectiveness Study of the Hydrus Microstent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery (HORIZON)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Primary Open Angle Glaucoma"
      ],
      "interventions": [
        {
          "name": "Hydrus Aqueous Implant",
          "type": "DEVICE"
        },
        {
          "name": "Cataract surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Ivantis, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "45 Years and older"
      },
      "enrollment_count": 1143,
      "start_date": "2012-01",
      "completion_date": "2020-06",
      "has_results": true,
      "last_update_posted_date": "2021-03-12",
      "last_synced_at": "2026-09-27T20:53:24.637Z",
      "location_count": 26,
      "location_summary": "Phoenix, Arizona • Tucson, Arizona • Fayetteville, Arkansas + 23 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01539239"
    },
    {
      "nct_id": "NCT07218783",
      "title": "Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cataract",
        "Glaucoma",
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "Bimatoprost Implant System",
          "type": "DRUG"
        },
        {
          "name": "SpyGlass IOL",
          "type": "DEVICE"
        },
        {
          "name": "Timolol Maleate Ophthalmic Solution, 0.5%",
          "type": "DRUG"
        },
        {
          "name": "Commercial IOL",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "SpyGlass Pharma, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2025-10-15",
      "completion_date": "2031-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-09-27T20:53:24.637Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07218783"
    },
    {
      "nct_id": "NCT05985304",
      "title": "Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cataract",
        "Corneal Astigmatism"
      ],
      "interventions": [
        {
          "name": "RayOne EMV Toric IOL",
          "type": "DEVICE"
        },
        {
          "name": "RayOne Monofocal IOL",
          "type": "DEVICE"
        },
        {
          "name": "Cataract Surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Rayner Intraocular Lenses Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 274,
      "start_date": "2023-08-10",
      "completion_date": "2024-10-23",
      "has_results": true,
      "last_update_posted_date": "2026-01-21",
      "last_synced_at": "2026-09-27T20:53:24.637Z",
      "location_count": 9,
      "location_summary": "Fayetteville, Arkansas • Grand Junction, Colorado • Alexandria, Minnesota + 6 more",
      "locations": [
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "Grand Junction",
          "state": "Colorado"
        },
        {
          "city": "Alexandria",
          "state": "Minnesota"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "West Fargo",
          "state": "North Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05985304"
    },
    {
      "nct_id": "NCT00425464",
      "title": "A Prospective Multicenter Clinical Study to Evaluate the Safety and Effectiveness of the Synchrony Dual Optic Intraocular Lens in Patients Undergoing Cataract Extraction",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cataract"
      ],
      "interventions": [
        {
          "name": "Standard Monofocal Intraocular Lens",
          "type": "DEVICE"
        },
        {
          "name": "Synchrony® Dual Optic Intraocular Lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Optics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 410,
      "start_date": "2005-11",
      "completion_date": "2013-04",
      "has_results": false,
      "last_update_posted_date": "2013-09-19",
      "last_synced_at": "2026-09-27T20:53:24.637Z",
      "location_count": 20,
      "location_summary": "Laguna Hills, California • Los Alamitos, California • Los Altos, California + 17 more",
      "locations": [
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Los Alamitos",
          "state": "California"
        },
        {
          "city": "Los Altos",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "West Hills",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00425464"
    },
    {
      "nct_id": "NCT02487160",
      "title": "Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cataracts",
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "SBL-3 multifocal intraocular lens",
          "type": "DEVICE"
        },
        {
          "name": "Control monofocal intraocular lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Lenstec Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 499,
      "start_date": "2015-08",
      "completion_date": "2019-08",
      "has_results": false,
      "last_update_posted_date": "2023-05-23",
      "last_synced_at": "2026-09-27T20:53:24.637Z",
      "location_count": 13,
      "location_summary": "Dothan, Alabama • Santa Maria, California • Cape Coral, Florida + 10 more",
      "locations": [
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "Santa Maria",
          "state": "California"
        },
        {
          "city": "Cape Coral",
          "state": "Florida"
        },
        {
          "city": "Fort Myers",
          "state": "Florida"
        },
        {
          "city": "Sebring",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02487160"
    }
  ]
}