{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Conventional+nicotine+content+cigarettes",
    "query": {
      "intervention": "Conventional nicotine content cigarettes"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-20T00:54:45.096Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02000921",
      "title": "Reduced Nicotine Content Cigarettes and Tobacco Switching Behaviors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Addiction",
        "Dual Tobacco Use"
      ],
      "interventions": [
        {
          "name": "VLNC cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Combusted Products",
          "type": "OTHER"
        },
        {
          "name": "Non-combusted products",
          "type": "OTHER"
        },
        {
          "name": "CN cigarettes",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 136,
      "start_date": "2013-12",
      "completion_date": "2016-09",
      "has_results": true,
      "last_update_posted_date": "2017-03-31",
      "last_synced_at": "2026-09-20T00:54:45.096Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02000921"
    },
    {
      "nct_id": "NCT02592772",
      "title": "Manipulating Tobacco Constituents in Male Menthol Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Reduced Nicotine Non-Menthol (RNC)",
          "type": "OTHER"
        },
        {
          "name": "Reduced Nicotine Menthol (RNC-Men)",
          "type": "OTHER"
        },
        {
          "name": "Conventional Nicotine Non-Menthol (CN)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "18 Years to 45 Years · Male only"
      },
      "enrollment_count": 118,
      "start_date": "2016-02-04",
      "completion_date": "2019-06",
      "has_results": false,
      "last_update_posted_date": "2020-04-09",
      "last_synced_at": "2026-09-20T00:54:45.096Z",
      "location_count": 2,
      "location_summary": "Farmington, Connecticut • Hartford, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02592772"
    },
    {
      "nct_id": "NCT01989507",
      "title": "Very Low-Nicotine Cigarettes in Smokers With SUD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine",
          "type": "DRUG"
        },
        {
          "name": "behavioral counseling for smoking cessation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 250,
      "start_date": "2014-04",
      "completion_date": "2021-05-31",
      "has_results": false,
      "last_update_posted_date": "2021-09-28",
      "last_synced_at": "2026-09-20T00:54:45.096Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01989507"
    },
    {
      "nct_id": "NCT03272685",
      "title": "Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Tobacco Smoking",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Very Low Nicotine Content Cigarettes",
          "type": "DRUG"
        },
        {
          "name": "Normal Nicotine Content Cigarettes",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 799,
      "start_date": "2018-06-01",
      "completion_date": "2023-01-10",
      "has_results": true,
      "last_update_posted_date": "2024-08-20",
      "last_synced_at": "2026-09-20T00:54:45.096Z",
      "location_count": 6,
      "location_summary": "San Francisco, California • Minneapolis, Minnesota • Durham, North Carolina + 3 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03272685"
    },
    {
      "nct_id": "NCT02048852",
      "title": "Manipulating Tobacco Constituents in Female Menthol Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Reduced Nicotine Content- Non Menthol",
          "type": "OTHER"
        },
        {
          "name": "Reduced Nicotine Content- Menthol",
          "type": "OTHER"
        },
        {
          "name": "Conventional Nicotine Content- Menthol",
          "type": "OTHER"
        },
        {
          "name": "Conventional Nicotine Content- Non Menthol",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 381,
      "start_date": "2014-07",
      "completion_date": "2020-07",
      "has_results": false,
      "last_update_posted_date": "2021-03-19",
      "last_synced_at": "2026-09-20T00:54:45.096Z",
      "location_count": 2,
      "location_summary": "Farmington, Connecticut • Hartford, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02048852"
    },
    {
      "nct_id": "NCT07142668",
      "title": "Effects of Tax Proposals and Cigarette Availability on Tobacco Purchasing",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Harm Reduction Tax - Normal Nicotine Cigarettes Available",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Harm Reduction Tax - Normal Nicotine Cigarettes Not Available",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Modified Risk Tobacco Product Tax - Normal Nicotine Cigarettes Available",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Modified Risk Tobacco Product Tax - Normal Nicotine Cigarettes Not Available",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine Content Tax - Normal Nicotine Cigarettes Available",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine Content Tax - Normal Nicotine Cigarettes Not Available",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tobacco Parity Tax - Normal Nicotine Cigarettes Available",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tobacco Parity Tax - Normal Nicotine Cigarettes Not Available",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 316,
      "start_date": "2025-08-14",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-09-20T00:54:45.096Z",
      "location_count": 2,
      "location_summary": "Buffalo, New York • Roanoke, Virginia",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07142668"
    },
    {
      "nct_id": "NCT01400815",
      "title": "Randomized Trial to Evaluate the Effectiveness of X-22 as a Smoking Cessation Aid",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "X-22 Smoking Cessation Product",
          "type": "DRUG"
        },
        {
          "name": "Active Control Cigarettes",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "22nd Century Limited, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 234,
      "start_date": "2011-07",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2021-11-19",
      "last_synced_at": "2026-09-20T00:54:45.096Z",
      "location_count": 3,
      "location_summary": "Sacramento, California • Metairie, Louisiana • Austin, Texas",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Metairie",
          "state": "Louisiana"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01400815"
    },
    {
      "nct_id": "NCT02599571",
      "title": "Effects of Nicotine Reduction on Smoking Behavior in ADHD Smokers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence",
        "ADHD"
      ],
      "interventions": [
        {
          "name": "Very low nicotine content cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Conventional nicotine content cigarettes",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 71,
      "start_date": "2016-03-30",
      "completion_date": "2019-09-12",
      "has_results": false,
      "last_update_posted_date": "2020-01-27",
      "last_synced_at": "2026-09-20T00:54:45.096Z",
      "location_count": 2,
      "location_summary": "Durham, North Carolina • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02599571"
    }
  ]
}