{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Core+Decompression",
    "query": {
      "intervention": "Core Decompression"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T13:41:32.692Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06123481",
      "title": "Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteonecrosis of the Femoral Head",
        "Avascular Necrosis of the Femoral Head"
      ],
      "interventions": [
        {
          "name": "Core Decompression",
          "type": "PROCEDURE"
        },
        {
          "name": "Core Decompression Procedure with Autologous Bone Marrow Aspirate Concentrate",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 192,
      "start_date": "2025-04-01",
      "completion_date": "2029-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-26",
      "last_synced_at": "2026-09-06T13:41:32.692Z",
      "location_count": 10,
      "location_summary": "Los Angeles, California • Stanford, California • Baltimore, Maryland + 6 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06123481"
    },
    {
      "nct_id": "NCT05706909",
      "title": "The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Avascular Necrosis",
        "Osteonecrosis"
      ],
      "interventions": [
        {
          "name": "Genex with ABMC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2023-02-08",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-04-17",
      "last_synced_at": "2026-09-06T13:41:32.692Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05706909"
    },
    {
      "nct_id": "NCT00006130",
      "title": "Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bone Avascular Necrosis",
        "Sickle Cell Anemia"
      ],
      "interventions": [
        {
          "name": "Core decompression",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "UCSF Benioff Children's Hospital Oakland",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "10 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "1999-06",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2017-02-15",
      "last_synced_at": "2026-09-06T13:41:32.692Z",
      "location_count": 2,
      "location_summary": "Oakland, California • Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00006130"
    },
    {
      "nct_id": "NCT06931301",
      "title": "Effect of HBOT on Femoral Head Avascular Necrosis (AVN)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteonecrosis",
        "Avascular Necrosis"
      ],
      "interventions": [
        {
          "name": "Hyperbaric Oxygen Therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2026-12",
      "completion_date": "2035-04",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-09-06T13:41:32.692Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06931301"
    },
    {
      "nct_id": "NCT02458937",
      "title": "Functional Outcomes Following Hip Core Decompression in Younger Participants With Osteonecrosis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteonecrosis"
      ],
      "interventions": [
        {
          "name": "Functional Mobility Assessment",
          "type": "OTHER"
        },
        {
          "name": "GAITRite® System",
          "type": "OTHER"
        },
        {
          "name": "Range of Motion",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "29 Years",
        "sex": "ALL",
        "summary": "8 Years to 29 Years"
      },
      "enrollment_count": 17,
      "start_date": "2015-06-05",
      "completion_date": "2018-09-26",
      "has_results": false,
      "last_update_posted_date": "2018-11-13",
      "last_synced_at": "2026-09-06T13:41:32.692Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02458937"
    },
    {
      "nct_id": "NCT03534141",
      "title": "Mild Hypothermia and Acute Kidney Injury in Liver Transplantation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cirrhosis",
        "End Stage Liver Disease",
        "Acute Kidney Injury",
        "Liver Transplant; Complications",
        "Chronic Kidney Diseases",
        "Hepatitis c",
        "Hepatitis B",
        "NASH - Nonalcoholic Steatohepatitis",
        "Alcoholic Cirrhosis",
        "Hepatocellular Carcinoma"
      ],
      "interventions": [
        {
          "name": "Esophageal cooling/warming device",
          "type": "DEVICE"
        },
        {
          "name": "Mild hypothermia",
          "type": "OTHER"
        },
        {
          "name": "Normothermia",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 175,
      "start_date": "2018-07-07",
      "completion_date": "2023-09-14",
      "has_results": true,
      "last_update_posted_date": "2025-05-16",
      "last_synced_at": "2026-09-06T13:41:32.692Z",
      "location_count": 3,
      "location_summary": "San Francisco, California • Aurora, Colorado • Houston, Texas",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03534141"
    },
    {
      "nct_id": "NCT00505219",
      "title": "Ixmyelocel-T Treatment of Patients With Osteonecrosis of the Femoral Head",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Osteonecrosis"
      ],
      "interventions": [
        {
          "name": "Ixmyelocel-T",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Standard of Care Only",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Vericel Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 11,
      "start_date": "2007-09",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2019-10-21",
      "last_synced_at": "2026-09-06T13:41:32.692Z",
      "location_count": 3,
      "location_summary": "Baltimore, Maryland • Minneapolis, Minnesota • Brooklyn, New York",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00505219"
    },
    {
      "nct_id": "NCT02662881",
      "title": "Biologically Assisted Core Decompression of the Femoral Head Using the PerFuse Instrument and BioCUE",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Avascular Necrosis of the Femoral Head"
      ],
      "interventions": [
        {
          "name": "PerFuse Percutaneous Decompression System",
          "type": "DEVICE"
        },
        {
          "name": "BioCUE Platelet Concentration System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2016-03",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2021-10-20",
      "last_synced_at": "2026-09-06T13:41:32.692Z",
      "location_count": 4,
      "location_summary": "St Louis, Missouri • Cleveland, Ohio • Philadelphia, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02662881"
    }
  ]
}