{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cryopreserved+amniotic+membrane",
    "query": {
      "intervention": "Cryopreserved amniotic membrane"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 15,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Cryopreserved+amniotic+membrane&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-17T08:54:32.141Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02571738",
      "title": "Study to Evaluate the Safety and Efficacy of CHAM* for the Treatment of Diabetic Foot Ulcers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Diabetic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "CHAM",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Osiris Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 108,
      "start_date": "2015-10",
      "completion_date": "2017-06",
      "has_results": false,
      "last_update_posted_date": "2017-10-06",
      "last_synced_at": "2026-09-17T08:54:32.141Z",
      "location_count": 18,
      "location_summary": "Tucson, Arizona • Carlsbad, California • Castro Valley, California + 15 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Carlsbad",
          "state": "California"
        },
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02571738"
    },
    {
      "nct_id": "NCT02764814",
      "title": "In Vivo Confocal Microscopic Analysis of Corneal Nerve Changes After ProKera Slim® for Dry Eye",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Eye Disease"
      ],
      "interventions": [
        {
          "name": "Cryopreserved amniotic membrane",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "BioTissue Holdings, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2015-07",
      "completion_date": "2016-11",
      "has_results": false,
      "last_update_posted_date": "2016-11-22",
      "last_synced_at": "2026-09-17T08:54:32.141Z",
      "location_count": 1,
      "location_summary": "Tinley Park, Illinois",
      "locations": [
        {
          "city": "Tinley Park",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02764814"
    },
    {
      "nct_id": "NCT04636229",
      "title": "Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Amniotic Suspension Allograft",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Organogenesis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 516,
      "start_date": "2020-12-14",
      "completion_date": "2025-08-19",
      "has_results": false,
      "last_update_posted_date": "2025-10-16",
      "last_synced_at": "2026-09-17T08:54:32.141Z",
      "location_count": 38,
      "location_summary": "Birmingham, Alabama • Mobile, Alabama • Glendale, Arizona + 30 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Tempe",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04636229"
    },
    {
      "nct_id": "NCT03113786",
      "title": "CLARIX™ 100 & CLARIX CORD 1K for Discectomy Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Protruded Disk"
      ],
      "interventions": [
        {
          "name": "CLARIX™100",
          "type": "OTHER"
        },
        {
          "name": "CLARIX CORD 1K",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Amniox Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 32,
      "start_date": "2011-11-02",
      "completion_date": "2020-04-21",
      "has_results": false,
      "last_update_posted_date": "2020-07-15",
      "last_synced_at": "2026-09-17T08:54:32.141Z",
      "location_count": 1,
      "location_summary": "Bensalem, Pennsylvania",
      "locations": [
        {
          "city": "Bensalem",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03113786"
    },
    {
      "nct_id": "NCT04222166",
      "title": "Registry of Amniotic Membrane: Evaluating Utilization and Outcomes in Various Applications",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Orthopedic Disorder",
        "Wound"
      ],
      "interventions": [
        {
          "name": "CAM",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "MED Institute Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2019-12-16",
      "completion_date": "2021-08-06",
      "has_results": false,
      "last_update_posted_date": "2021-08-27",
      "last_synced_at": "2026-09-17T08:54:32.141Z",
      "location_count": 2,
      "location_summary": "Gulf Breeze, Florida • Voorhees Township, New Jersey",
      "locations": [
        {
          "city": "Gulf Breeze",
          "state": "Florida"
        },
        {
          "city": "Voorhees Township",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04222166"
    },
    {
      "nct_id": "NCT05148507",
      "title": "Optimization of the Ocular Surface Prior to Cataract Surgery Using PROKERA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cataract",
        "Dry Eye Syndromes",
        "Cataract Senile",
        "Dry Eye"
      ],
      "interventions": [
        {
          "name": "PROKERA",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jeff Wongskhaluang",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 43,
      "start_date": "2021-11-04",
      "completion_date": "2025-01-21",
      "has_results": false,
      "last_update_posted_date": "2025-03-11",
      "last_synced_at": "2026-09-17T08:54:32.141Z",
      "location_count": 1,
      "location_summary": "Olathe, Kansas",
      "locations": [
        {
          "city": "Olathe",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05148507"
    },
    {
      "nct_id": "NCT01708187",
      "title": "The Role of C-HAM in the Surgical Repair of Peroneal Tendons: An Infrared Thermography Model",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tendon Tears"
      ],
      "interventions": [
        {
          "name": "Clarix™1k graft",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Orthopedic Foot and Ankle Center, Ohio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2012-10",
      "completion_date": "2014-11",
      "has_results": true,
      "last_update_posted_date": "2016-11-03",
      "last_synced_at": "2026-09-17T08:54:32.141Z",
      "location_count": 1,
      "location_summary": "Westerville, Ohio",
      "locations": [
        {
          "city": "Westerville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01708187"
    },
    {
      "nct_id": "NCT03379324",
      "title": "Efficacy of an Amniotic Fluid Derived Allograft, (FlōGraft®) in Rotator Cuff Repairs: A Prospective Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rotator Cuff Tear",
        "Fatty Atrophy"
      ],
      "interventions": [
        {
          "name": "Superiority of augmented repairs",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Fat degeneration of supraspinatus muscle",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Applied Biologics, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 260,
      "start_date": "2017-03-24",
      "completion_date": "2019-09-30",
      "has_results": false,
      "last_update_posted_date": "2017-12-20",
      "last_synced_at": "2026-09-17T08:54:32.141Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03379324"
    },
    {
      "nct_id": "NCT02166294",
      "title": "NEOX® CORD 1K vs Standard of Care in Non-healing Diabetic Foot Ulcers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Foot Ulcer, Diabetic"
      ],
      "interventions": [
        {
          "name": "NEOX® CORD 1K",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care (Pressure Bandage)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Amniox Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 18,
      "start_date": "2014-06",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2017-06-27",
      "last_synced_at": "2026-09-17T08:54:32.141Z",
      "location_count": 3,
      "location_summary": "Tucson, Arizona • Castro Valley, California • Newnan, Georgia",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "Newnan",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02166294"
    },
    {
      "nct_id": "NCT00915759",
      "title": "Sutureless Cryopreserved Amniotic Membrane Graft (ProKera) and Wound Healing After Photorefractive Keratectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Corneal Wound Healing"
      ],
      "interventions": [
        {
          "name": "ProKera",
          "type": "DEVICE"
        },
        {
          "name": "Bandage contact lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Walter Reed National Military Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2009-06",
      "completion_date": "2015-07",
      "has_results": true,
      "last_update_posted_date": "2025-02-07",
      "last_synced_at": "2026-09-17T08:54:32.141Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00915759"
    }
  ]
}